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Abdominal Pain Articles & Analysis

26 news found

MorphoSys Presents New Longer-term Phase 2 Results on Pelabresib in Myelofibrosis, Including Potential Disease-Modifying Activity, at ASH 2022

MorphoSys Presents New Longer-term Phase 2 Results on Pelabresib in Myelofibrosis, Including Potential Disease-Modifying Activity, at ASH 2022

The most common (≥25%) nonhematologic treatment-emergent AEs of any grade were diarrhea (43%), respiratory tract infection (41%), asthenic conditions (38%), musculoskeletal pain (32%), constipation (30%), nausea (29%), dizziness (27%) and abdominal pain (26%). ...

ByMorphoSys AG


FDA Approves Taiho’s LYTGOBI® (futibatinib) Tablets for Previously Treated, Unresectable, Locally Advanced or Metastatic Intrahepatic Cholangiocarcinoma

FDA Approves Taiho’s LYTGOBI® (futibatinib) Tablets for Previously Treated, Unresectable, Locally Advanced or Metastatic Intrahepatic Cholangiocarcinoma

The most common (≥20%) adverse reactions were nail toxicity, musculoskeletal pain, constipation, diarrhea, fatigue, dry mouth, alopecia, stomatitis, dry skin, arthralgia, dysgeusia, abdominal pain, dry eye, nausea, decreased appetite, urinary tract infection, palmar-plantar erythrodysesthesia syndrome, and vomiting. ...

ByTaiho Oncology, Inc.


Alnylam Presents Additional Results from the APOLLO-B Phase 3 Study of Patisiran in Patients with ATTR Amyloidosis with Cardiomyopathy at Heart Failure Society of America Annual Meeting

Alnylam Presents Additional Results from the APOLLO-B Phase 3 Study of Patisiran in Patients with ATTR Amyloidosis with Cardiomyopathy at Heart Failure Society of America Annual Meeting

– New Data Further Support Potential for Patisiran to be an Effective Treatment for Cardiomyopathy of ATTR Amyloidosis – – Data from Exploratory Endpoints, Including Cardiac Biomarkers and Imaging, Suggest Favorable Impact of Patisiran on Measures of Cardiac Stress, Injury, Structure, and Function at Month 12 – – Treatment with Patisiran Demonstrated Generally ...

ByAlnylam Pharmaceuticals, Inc.


Alnylam to Present Additional Data from the APOLLO-B Phase 3 Study of Patisiran in Patients with ATTR Amyloidosis with Cardiomyopathy at the Heart Failure Society of America Annual Scientific Meeting 2022

Alnylam to Present Additional Data from the APOLLO-B Phase 3 Study of Patisiran in Patients with ATTR Amyloidosis with Cardiomyopathy at the Heart Failure Society of America Annual Scientific Meeting 2022

– Company to Webcast Investor Event on September 30th at 8:00 p.m. ET – CAMBRIDGE, Mass.--(BUSINESS WIRE)--Sep. 13, 2022-- Alnylam Pharmaceuticals, Inc. (Nasdaq: ALNY), the leading RNAi therapeutics company, announced today that the Company will present additional data from the APOLLO-B Phase 3 study of patisiran, an investigational RNAi therapeutic in development for the treatment ...

ByAlnylam Pharmaceuticals, Inc.


The Essential Guide to Food Allergies

The Essential Guide to Food Allergies

The IgE-mediated allergies include food allergy manifested as angioedema, nausea, abdominal pain, anaphylaxis including wheat dependent exercise-induced anaphylaxis, respiratory allergy as well as skin allergy. ...

ByHYCOR Biomedical


Fecal biomarkers - diagnostic possibilities in the context of inflammatory bowel disease

Fecal biomarkers - diagnostic possibilities in the context of inflammatory bowel disease

During relapses, acute inflammation occurs in the bowel of IBD patients, leading to typical symptoms such as chronic diarrhea, abdominal pain, and/or weight loss. However, these symptoms are not specific to IBD, but can also be caused, for example, by irritable bowel syndrome (IBS). ...

ByImmundiagnostik AG


Citrine Medicine Announces Approval of Wakix (pitolisant) for Named Patient Program in China

Citrine Medicine Announces Approval of Wakix (pitolisant) for Named Patient Program in China

Important Safety Information In clinical trials conducted in patients with narcolepsy, the most frequent adverse drug reactions (ADRs) reported with pitolisant were insomnia (8.4%), headache (7.7%), nausea (4.8%), anxiety (2.1%), irritability (1.8%), dizziness (1.4%), depression (1.3%), tremor (1.2%), sleep disorders (1.1%), fatigue (1.1%), vomiting (1.0%), vertigo (1.0%), dyspepsia (1.0%), ...

ByRareStone Group


EvoEndo Poised to Transform Clinical Endoscopy Practice with the EvoEndo Single-Use Unsedated Transnasal Endoscopy (TNE) System

EvoEndo Poised to Transform Clinical Endoscopy Practice with the EvoEndo Single-Use Unsedated Transnasal Endoscopy (TNE) System

Unsedated TNE can be used to evaluate and diagnose a wide range of upper GI conditions that may require frequent monitoring including eosinophilic esophagitis (EoE), dysphagia, celiac disease, gastroesophageal reflux disease, Barrett’s esophagus, malabsorption, and abdominal pain. “My family has extensive experience with sedated endoscopies, and from ...

ByEvoEndo


Palisade Bio (Nasdaq: PALI) Announces Analysis Demonstrating LB1148 Reduced The Extent And Severity Of Post-Surgical Intraabdominal Adhesions By 93%

Palisade Bio (Nasdaq: PALI) Announces Analysis Demonstrating LB1148 Reduced The Extent And Severity Of Post-Surgical Intraabdominal Adhesions By 93%

” Studies LBS-IST-POI-101 and LBS-POI-201-CN (PROFILE-CN) assessed the efficacy of LB1148 to reduce the formation of adhesions in subjects undergoing abdominal surgery. Study LBS-IST-POI-101 was a Phase 1, single-center, open-label, study enrolling 11 subjects undergoing GI surgery. ...

ByPalisade Bio


UroGen Announces Data that Shows In-Office Nephrostomy Tube Administration of Jelmyto® is Efficient for Doctors and Well Tolerated by Patients

UroGen Announces Data that Shows In-Office Nephrostomy Tube Administration of Jelmyto® is Efficient for Doctors and Well Tolerated by Patients

UroGen Pharma Ltd. (Nasdaq: URGN), a biotech company dedicated to creating novel solutions that treat urothelial and specialty cancers, today announced the first published report of real-world experience utilizing the antegrade approach for Jelmyto® (mitomycin) for pyelocalyceal solution administration in the Journal of Urology online on February 7, 2022. This report provides a stepwise ...

ByUroGen Pharma, Inc.


Lupin Signs Promotional Agreement with Exeltis on SOLOSEC® expanding access for Adult Women Suffering with Bacterial Vaginosis and Adults with Trichomoniasis

Lupin Signs Promotional Agreement with Exeltis on SOLOSEC® expanding access for Adult Women Suffering with Bacterial Vaginosis and Adults with Trichomoniasis

Most common adverse reactions observed in clinical trials (incidence ≥2%) were vulvovaginal candidiasis, headache, nausea, dysgeusia, vomiting, diarrhea, abdominal pain, and vulvovaginal pruritus. To report SUSPECTED ADVERSE REACTIONS, contact Lupin Pharmaceuticals, Inc. at 1-844-SOLOSEC (1-844-765-6732) or FDA at 1-800-FDA-1088 or www.fda.gov/medwatch. ...

ByLupin Limited


INOVIO Collaborates with GuardRX and Geneva University Hospitals for Heterologous Booster Clinical Trial of its Ebola DNA Vaccine Candidate, INO-4201

INOVIO Collaborates with GuardRX and Geneva University Hospitals for Heterologous Booster Clinical Trial of its Ebola DNA Vaccine Candidate, INO-4201

EVD is characterized by fatigue, vomiting, diarrhea, abdominal pain, severe hemorrhagic fever, and very often death [Feldmann et al New Eng J Med (2020)]. ...

ByINOVIO Pharmaceuticals


Gynesonics Announces First Office-Based Sonata Procedure in the State of Texas

Gynesonics Announces First Office-Based Sonata Procedure in the State of Texas

Sonata is the only fibroid ablation system that does not require incisions or abdominal surgery. Sonata has been uniquely designed to help patients gain access to care through multiple sites of service, supporting rapid adoption around the ...

ByGynesonics


Gynesonics Announces FDA Clearance of Next Generation Sonata System

Gynesonics Announces FDA Clearance of Next Generation Sonata System

Women with symptomatic fibroids may present one or more of the following: Abnormal uterine bleeding/menorrhagia Abdominopelvic pain/pressure Increased abdominal girth Urinary frequency Constipation Subfertility Pregnancy complications Dyspareunia (painful intercourse) About Gynesonics Gynesonics is a women’s healthcare company ...

ByGynesonics


Vedanta Biosciences Presents New Data from Phase 1 Study of VE202, Its Rationally-Defined Consortium for the Treatment of Inflammatory Bowel Disease, at the International Human Microbiome Consortium Congress 2021 (IHMC)

Vedanta Biosciences Presents New Data from Phase 1 Study of VE202, Its Rationally-Defined Consortium for the Treatment of Inflammatory Bowel Disease, at the International Human Microbiome Consortium Congress 2021 (IHMC)

The most common forms of IBD are ulcerative colitis and Crohn's disease, which are both characterized by diarrhea, rectal bleeding, abdominal pain, fatigue and weight loss that can lead to life-threatening complications due to chronic inflammation of the digestive tract. ...

ByVedanta Biosciences, Inc


ImmunogenX and Mayo Clinic Successfully Complete the CeliacShield Trial

ImmunogenX and Mayo Clinic Successfully Complete the CeliacShield Trial

Measurements of gluten immunogenic peptides in urine showed reduction of gluten of >90% for latiglutenase vs. placebo with p = 0.0008 (ANCOVA). Symptom attenuation was 93% (abdominal pain), 53% (bloating) and 99% (tiredness) with a 3 x 2-week trend-line significance of p = 0.0142, 0.0298 and 0.0018 (unpaired, 2-tailed t-test), respectively. ...

ByEntero Therapeutics, Inc.


Lilly`s Mirikizumab Helps Patients Achieve Clinical Remission and Improves Symptoms in Adults with Ulcerative Colitis in 12-Week Phase 3 Induction Study

Lilly`s Mirikizumab Helps Patients Achieve Clinical Remission and Improves Symptoms in Adults with Ulcerative Colitis in 12-Week Phase 3 Induction Study

UC is a chronic inflammatory disease of the large intestine, also referred to as the colon, that affects the lining of the colon and may cause small sores, or ulcers, to form.i This inflammation can cause abdominal pain, frequent and urgent trips to the bathroom, bloody stools and incontinence.1 UC can cause significant and debilitating disruptions in daily life. ...

ByEli Lilly and Company


ImmunogenX Publishes in Celiac Disease Journal

ImmunogenX Publishes in Celiac Disease Journal

The novel algorithm used baseline and placebo data from the CeliAction® trial (ALV003-1221, NCT01917630). The symptoms evaluated were abdominal pain, bloating and tiredness. The study found that episodic gluten ingestion of 200-400 mg can trigger each of these symptoms (mild or greater severity) and which occur multiple times per week in generally symptomatic ...

ByEntero Therapeutics, Inc.


FDA Clears First Blood Test for Identifying a Novel Allergic Sensitization to Red Meat

FDA Clears First Blood Test for Identifying a Novel Allergic Sensitization to Red Meat

Symptoms range from hives and itching, to abdominal pain, nausea or vomiting. In severe cases the allergy can cause anaphylaxis which can be potentially fatal. ...

ByThermo Fisher Scientific, LIMS & Laboratory Software


FDA Approves BAVENCIO (avelumab) plus Axitinib Combination for Patients with Advanced Renal Cell Carcinoma

FDA Approves BAVENCIO (avelumab) plus Axitinib Combination for Patients with Advanced Renal Cell Carcinoma

The most common adverse reactions (≥20%) were diarrhea, fatigue, hypertension, musculoskeletal pain, nausea, mucositis, palmar-plantar erythrodysesthesia, dysphonia, decreased appetite, hypothyroidism, rash, hepatotoxicity, cough, dyspnea, abdominal pain and headache. ...

BySiemens AG

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