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Heart Muscle Articles & Analysis
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The second, REVeRT (REconstitution Via mRNA Trans-splicing) technology platform, allows efficient reconstitution of large genes (>5Kb) in various tissues such as retina, brain, heart, liver, and skeletal muscle. The third, AAV Transactivation is a CRISPR-Cas–based AAV gene therapy platform that enables to regulate one or multiple genes in vivo. ...
CardioWise, Inc. has recently completed development of the first fully integrated version of its Multiparametric Strain Analysis Software (MPSA™), which is uniquely capable of analyzing the three-dimensional motion of the heart that is acquired from cardiac MRI images and then comparing the analysis at 15,300 points to the motion of a normal heart model. ...
The company also plans other clinical studies in additional cardiovascular indications, including heart failure caused by ischemic heart disease and as adjunctive therapy to percutaneous coronary intervention. ...
SQuEEZ is based on the ability in high resolution cardiac CT scans to track points on the endocardium as they move during the contraction of the heart to allow quantitative assessment of regional myocardial heart wall motion. The analysis of four dimensional SQuEEZ parameters has the potential to improve the ability to quantify accurately the regional myocardial ...
– July 12, 2022 – Ancora Heart, Inc., a company developing a novel device-based therapy to address heart failure, today announced that the U.S. ...
” Individuals with refractory angina experience pressure or intense pain in the chest due to insufficient blood flow to the heart muscle. These symptoms can severely impact quality of life and may worsen comorbidities. ...
Barostim is also the recipient of the Centers for Medicare and Medicaid Services (CMS) outpatient Transitional Pass-Through Payment Status (TPT) and inpatient New Technology Add-On Payment (NTAP). About Heart Failure Heart failure is a chronic, progressive condition in which the heart muscle is unable to pump enough blood to ...
ByCVRx
“In contrast, because we can inject XC001 directly into the heart, we can dramatically reduce overall viral particle loads and systemic exposure while increasing ...
“Pompe disease is a progressive, life-limiting neuromuscular disorder caused by the accumulation of lysosomal glycogen in cardiac and skeletal muscle as well as the CNS. As glycogen accumulates, patients experience severe and progressive myopathy, leading to muscle weakness, loss of motor function and ultimately cardiorespiratory failure,” said ...
Heart failure is a chronic, progressive condition in which the heart muscle is unable to pump enough blood to meet the body's needs for blood and oxygen. Barostim works by stimulating baroreceptors - natural sensors in the body that tell the nervous system how to regulate heart, kidney and vascular function. These effects reduce ...
ByCVRx
If the blocked blood vessel is pierced with a fine wire mesh, a large amount of blood is supplied to the stopped heart. When this happens, the amount of free radicals suddenly increases and the heart muscle is damaged. Bilirubin, which has an antioxidant effect, removes free radicals and minimizes damage to the heart ...
Specifically, the study demonstrated that young men in the advanced stages of DMD experienced improvements in both skeletal and cardiac muscle function after receiving four doses of CAP-1002 over the course of one year. ...
Eligible patients receive a high dose of cells using an intramyocardial delivery system that has been shown in published literature to present the lowest risk to patients for biotherapeutic delivery[1] and to be three to six times more efficient at delivering cells to the heart muscle than other methods.[2] This approach allows the patient to be discharged from ...
About Cardiomyopathy Cardiomyopathy represents a collection of diverse conditions of the heart muscle. These diseases have many causes, and symptoms that affect people of all ages and races. When cardiomyopathy occurs, the normal muscle in the heart can thicken, stiffen, thin out, or fill with substances the body produces that ...
The 2021 class of Leonhardt’s Launchpads Accelerator graduates include: MyoStim ED with ErectiStimTM: MyoStim ED is the first intervention for erectile dysfunction (ED) designed to address all major causes of ED: impaired blood flow, damaged blood vessels, nerve damage, and muscle deterioration. MyoStim ED utilizes non-invasive bioelectric stimulation sequences designed ...
CardiAMP Cell Therapy uses a patient’s own (autologous) bone marrow cells delivered to the heart in a minimally invasive, catheter-based procedure to potentially stimulate the body’s natural healing response. ...
The investigational gene therapy will be administered directly to the muscle tissue of the heart by an experienced cardiac surgeon. The EXACT Trial was initiated in 2020 and is ongoing at top cardiovascular research sites across the United States. About Chronic Refractory Angina Chronic angina pectoris occurs when the heart ...
As a small molecule, HST5040 has the ability to distribute to all affected tissues and thus has the potential to be active throughout the body, including the liver, kidneys, brain, heart and muscles. HST5040 is designed for convenient daily administration at home as a liquid formulation taken either orally or through a gastric feeding tube. ...
” About Cardiomyopathy Cardiomyopathy represents a collection of diverse conditions of the heart muscle. These diseases have many causes, and symptoms that affect people of all ages and races. When cardiomyopathy occurs, the normal muscle in the heart can thicken, stiffen, thin out, or fill with substances the body ...
Dillon will be building BioVentrix into a high-performance heart failure therapy company, leading the team toward the achievement of its mission while meeting or exceeding its annual business goals. ...