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MedChemExpress - Model BAY 2965501 - 2732902-08-6
BAY 2965501 is a potent and selective diacylglycerol kinase zeta (DGKζ) inhibitor. BAY 2965501 induces pERK activation. BAY 2965501 can be used for the research of cancer[1].MCE products for research use only. We do not sell to patients.
BAY 2965501
MCE China:BAY 2965501
Brand:MedChemExpress (MCE)
Cat. No.HY-153343
CAS:2732902-08-6
Purity:99.43%
Storage:Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Shipping:Room temperature in continental US; may vary elsewhere.
Description:BAY 2965501 is a potent and selective diacylglycerol kinase zeta (DGKζ) inhibitor. BAY 2965501 induces pERK activation. BAY 2965501 can be used for the research of cancer.
In Vitro:BAY 2965501 increases natural killer cell- and T-cell-mediated tumor cell killing, and enhances IL2-induced natural killer cell activation[2].
In Vivo:BAY-2965501 inhibits tumor growth inhibition in an F9 testicular teratoma model, and the combination of BAY-2965501 with immune checkpoint blockade results in additive or synergistic effects[3].
IC50 & Target:DGKζ[1] In Vitro BAY 2965501 increases natural killer cell- and T-cell-mediated tumor cell killing, and enhances IL2-induced natural killer cell activation[2]. MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. 0 --> BAY 2965501 Related Antibodies
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References:
[3]. Schlicher L, et al. Small molecule inhibitors for cancer immunotherapy and associated biomarkers - the current status. Front Immunol. 2023 Oct 31;14:1297175. [Content Brief]
Brand introduction:
• MCE (MedChemExpress) has a global exclusive compound library of more than 200 kinds, and we are committed to providing the most comprehensive range of high-quality small molecule active compounds for scientific research customers around the world;
• More than 50,000 highly selective inhibitors and agonists are involved in various popular signaling pathways and disease areas;
• The products cover a variety of recombinant proteins, peptides, commonly used kits, more PROTAC, ADC and other characteristic products, widely used in new drug research and development, life science and other scientific research projects;
• Provide virtual screening, ion channel screening, metabolomics analysis detection analysis, drug screening and other professional technical services;
• It has a professional experimental center and strict quality control and verification system;
• Provide LC/MS, NMR, HPLC, chiral analysis, elemental analysis and other quality inspection reports to ensure the high purity and high quality of products;
• The biological activity of the products has been verified by the experiments of customers in various countries;
• A variety of top journals such as Nature, Cell, Science and pharmaceutical patents have included the scientific research results of MCE customers;
• Our professional team tracks the latest pharmaceutical and life science research and provides you with the latest active compounds in the world;
• It has established long-term cooperation with the world's major pharmaceutical companies and well-known scientific research institutions。