BlueSky Immunotherapies GmbH

BlueSkyInterferon-inducing Viral Vectors (delNS)

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The high level of interferon induced by the delNS vector activates immunological defence reactions against cancer. It also stimulates the production of antiviral molecules.

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Immunostimulation / Immunomodulation

  • NK – activates Natural Killer Cells
  • CTL – activates Cytotoxic T-Cells
  • DC – activates Dendritic Cells
  • Treg – inhibits Immunosuppressive Regulatory T-Cells
  • ΜΦ – activates Macrophage

Antiviral molecules / Inhibition of viral replication

  • ISG15 – Interferon stimulated gene 15
  • OAS – Oligoadenylate synthetase
  • PKR – Protein Kinase R
  • Mx – Interferon-induced GTP binding protein