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Drug Discovery Development Equipment Supplied In North America
14 equipment items found
by:Valo Health, Inc. based inBoston, MASSACHUSETTS (USA)
Opal is the first end-to-end integrated drug discovery & development platform. Traditional, linear approaches to target discovery and drug development have created sub-optimized systems that are intrinsically disintegrated and ...
by:Sword Diagnostics, Inc. based inCarmel, INDIANA (USA)
Sword scientists specialize in the development of qualitative or quantitative bioanalytical methods that measure cellular biomolecules active in a specific disease state. Cell-based assays are bioanalytical methods that measure the presence, amount, or activity of biomolecules in cells, cell fractions, nuclear extracts, tissue extracts, or cell extracts. In pharmaceutical ...
Manufactured by:XILIS, Inc. based inDurham, NORTH CAROLINA (USA)
Overcoming major limitations of widely used, yet limited, models including xenografts and organoids, MOS offers unprecedented speed, scalability, and predictivity in a small-scale model, opening up tremendous opportunities using patient-derived micro-tumors in drug development and discovery as well as drug prioritization assays ...
Manufactured by:BioGenex Laboratories based inFremont, CALIFORNIA (USA)
Xmatrx® Infinity is a fully automated molecular pathology workstation designed to accelerate life sciences research, drug discovery and development. It is an open system that allows simultaneous optimization of 40 assay parameters in a single run. With 40 individually operable and thermally-cyclable slide blocks, it is feasible to perform ...
Manufactured by:Molecular Devices, LLC. based inSan Jose, CALIFORNIA (USA)
Organoids are derived from biopsies and tissues sampled from patients or subjects (usually termed Patient-Derived Organoids, or PDOs). PDOs are self-organising cell structures that mimic the tissue or organ from which they are derived – they are often termed ‘mini-organs’. ...
Manufactured by:Promega Corporation based inMadison, WISCONSIN (USA)
4-1BB (CD137/TNFRSF9), a member of the tumor necrosis factor receptor superfamily, is an inducible co-stimulatory receptor expressed on T cells, natural killer (NK) cells and innate immune cell populations. When present on the cell surface, 4-1BB interacts with 4-1BB ligand (4-1BBL) and induces subsequent cell proliferation and production of interferon gamma (IFNγ) and interleukin-2 (IL-2), ...
Manufactured by:Recursion based inSalt Lake City, UTAH (USA)
Turning drug discovery into a search problem; Central to our mission is the Recursion Operating System (OS), an integrated, multi-faceted system for generating, analyzing and deriving insight from massive biological and chemical datasets to industrialize drug discovery composed ...
Manufactured by:Agilent Technologies, Inc. based inSanta Clara, CALIFORNIA (USA)
BioTek Cytation 7 cell imaging multimode reader combines automated digital upright and inverted widefield microscopy with conventional multimode microplate reading. Cytation 7 includes continually variable bandpass monochromators for versatility and performance for general multimode plate reader applications. The inverted microscopy module provides sample visualization and the upright microscopy ...
Manufactured by:MedChemExpress LLC (MCE) based inMonmouth Junction, NEW JERSEY (USA)
Pimitespib (TAS-116) is an oral bioavailable, ATP-competitive, highly specific HSP90α/HSP90β inhibitor (Kis of 34.7 nM and 21.3 nM, respectively) without inhibiting other HSP90 family proteins such as GRP94[1]. Pimitespib demonstrates less ocular ...
Manufactured by:MedChemExpress LLC (MCE) based inMonmouth Junction, NEW JERSEY (USA)
3-Aminobenzoic acid (3-ABA) is an orally active anti-inflammatory agent targeting the tight junction (TJ) regulatory pathways in intestinal epithelial cells. 3-Aminobenzoic acid improves intestinal inflammation by enhancing intestinal barrier integrity and reducing epithelial permeability. It can be used in studies related to improving gut health. Additionally, 3-Aminobenzoic acid analogs can act ...
Manufactured by:Tempo Bioscience, Inc based inSan Francisco, CALIFORNIA (USA)
Astrocytes, also known as Astroglia, belong to the family of glial cells in the human central and peripheral nervous system. They have been shown to have central roles in the maintenance of neuronal metabolism and neurotransmitter synthesis. They have been implicated in many human neurodegenerative disorders such as multiple sclerosis, amyotrophic lateral sclerosis (ALS), Alzheimer’s ...
Manufactured by:Tempo Bioscience, Inc based inSan Francisco, CALIFORNIA (USA)
Cardiomyocytes are cardiac muscle cells. They are terminally differentiated and facilitate contractile forces (“beatings”) of the heart. Grown in vitro as a monolayer sheath, cardiomyocytes are connected by gap junction proteins that help synchronize contraction-relaxation cycles of the cardiomyocytes. Cardiomyocytes may be used in various in vitro or in vivo studies; ...
Manufactured by:Juvena Therapeutics, inc. based inRedwood City, CALIFORNIA (USA)
Secreted proteins are a proven class of biologics with tremendous therapeutic potential, as they regulate tissue repair and regeneration, organ development, and immune response to disease. The characteristics of secreted proteins render them a rich pool of drug candidates for chronic and age-related diseases. Our therapeutic approach is to unlock the potential of these proteins, starting with ...
Manufactured by:Tempo Bioscience, Inc based inSan Francisco, CALIFORNIA (USA)
Blood Brain Barrier (BBB) is an important feature of the cerebral vasculature. Cells that form the barrier are called Brain Microvascular Endothelial Cells (BMECs). The barrier regulates the transport of molecular chemicals (including metabolites) and cells between the brain and blood. The barrier’s functionality is conducted via specialized groups of tight junction proteins and ...