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Gene Editing Therapy Equipment & Supplies
124 equipment items found
Manufactured by:SeQure Dx, Inc. based inWaltham, MASSACHUSETTS (USA)
GUIDE-seq and ONE-seq are used to nominate potential off-target editing sites in cellular models and free DNA, respectively. ONE-seq has the advantages that it can be used to assess adenine and cytosine base editors, it allows variant-aware analysis of multiple genomes simultaneously (thousands), and it detects a broader spectrum of off-target sites. Target cells or tissues are then tested to ...
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Manufactured by:AB Sciex LLC based inFramingham, MASSACHUSETTS (USA)
Perform consistent and compliant biotherapeutics characterization faster than ever. With the PA 800 Plus system, you can confidently safeguard the success of your biologics. Run multiple characterizations from a single system that biopharma labs depend on, and produce qualitative and quantitative analyses, with speed and ...
Manufactured by:AD.TECH – Albian Equipment based inBilbao, SPAIN
A physical barrier between a process that may require sterility and pressurisation, either positive or negative, from the outside environment, ensuring the necessary protection, reducing potential contamination and risks of cross-contamination and achieving the required air quality in the respective areas. ...
Manufactured by:Tectonic Therapeutic, Inc. based in
AVROBIO’s investigational gene therapy for Fabry disease is currently being studied in two clinical trials. An investigator-sponsored Phase 1 trial in Canada is fully enrolled, with five patients dosed. Nine treatment-naïve patients have been dosed in the FAB-GT Phase 2 trial, which continues to enroll in Australia, the U.S. and ...
Manufactured by:Tectonic Therapeutic, Inc. based in
AVROBIO’s investigational gene therapy for cystinosis is being studied in a Phase 1/2 investigational trial sponsored by the University of California, San Diego. The first patient was dosed in October 2019. The single-arm trial is expected to enroll four adults and a potential follow-on cohort of two adults or adolescents at least 14 years of age who are currently being treated with ...
Manufactured by:ASC Therapeutics based inMilpitas, CALIFORNIA (USA)
Genetic diseases are caused by defective genes. Gene replacement therapy aims to treat such diseases by introducing a corrective gene into a patient’s body; the corrective gene can be a normal copy of the defective gene, or a copy that is engineered to provide enhanced biological activity; our focus for gene replacement therapy starts by identifying gene variants with superior therapeutic ...
Manufactured by:Obsidian Therapeutics, Inc. based inCambridge, MASSACHUSETTS (USA)
Engineered with membrane-bound IL15, Eliminates toxic IL2 regimen, increasing patient accessibility to TIL therapy, Drives improved persistence, IL15 expression controlled by acetazolamide (ACZ), via cytoDRiVE® ...
Manufactured by:Tectonic Therapeutic, Inc. based in
AVROBIO has a preclinical research program for an investigational gene therapy for Gaucher disease type ...
Manufactured by:Tectonic Therapeutic, Inc. based in
AVROBIO has a preclinical research program for a gene therapy for Pompe disease. We have shown a favorable preclinical safety and efficacy profile in a mouse model of Pompe ...
Manufactured by:Tectonic Therapeutic, Inc. based in
AVROBIO’s investigational gene therapy for Gaucher disease is being studied in a Phase 1/2 clinical trial to evaluate the safety and efficacy in individuals with Gaucher disease type 1. The trial is now enrolling in Canada, Australia and the U.S. The trial is intended to recruit 8 to 16 individuals between the ages of 16 and 35 with Gaucher disease type 1, including both those who are ...
Manufactured by:Ziphius Vaccines NV based inMerelbeke, BELGIUM
Ziphius Vaccines is a self-amplifying RNA company developing vaccines for infectious diseases and gene supplementation therapies, aiming to create a new generation of medical ...
Manufactured by:Novartis International AG based inBasel, SWITZERLAND
Our investigational gene therapy, GT005, is designed to restore balance to a part of our immune system called the complement ...
Manufactured by:ProBioGen AG based inBerlin, GERMANY
Typically, cell line development relies on the integration of transgenes anywhere into the genome. How active that spot is, is a matter of luck. Winning clones are identified in extensive screens. You, though, want to position your transgene where the action is to yield the best results for your product. ...
Manufactured by:SpliceBio based inBarcelona, SPAIN
SpliceBio is developing several gene therapy programs aimed at treating genetic diseases by exploiting our proprietary Protein Splicing platform. Our lead program is in Stargardt disease, the most common inherited retinal disorder caused by mutations in a single gene, ABCA4, which at 6.8 kb is too large for single AAV ...
by:Thermo Fisher Scientific, LIMS & Laboratory Software based inPhiladelphia, PENNSYLVANIA (USA)
Identify an optimal formulation for your target cell line. Manufacturers of adeno-associated viral (AAV) vectors need to scale up quickly and cost-effectively to meet the increasing demand from the gene therapy market. But testing and optimizing multiple catalog media takes time and expertise. What if you had a panel of media and an expert in media optimization to help ...
Manufactured by:Charter Medical, LLC based inWinston-Salem, NORTH CAROLINA (USA)
Charter Medical’s Advect® Fluid Transfer Sets are designed to support the quality and manufacturing requirements of personalized care. The transfer sets are intended for sterile transfer of bone marrow mononuclear cells from one container to another. ...
Manufactured by:Polysciences, Inc. based inWarrington, PENNSYLVANIA (USA)
MAXgene GMP Transfection Reagent is a cGMP transfection reagent for the development and manufacturing of viral vectors for cell-and gene-based therapies. It is an ideal reagent in HEK293 and CHO systems for the manufacture of AAVs, LVs and recombinant proteins. MAXgene GMP capitalizes on the efficiency and scalability of Polysciences’ PEI MAX while adding the validation process and ...
Manufactured by:Inovarion based inParis, FRANCE
Sensitized to the ethics of animal experimentation and to the respect of the 3Rs principles (replacement, reduction, refinement), Inovarion’s experts can assist you in your experiments requiring the use of animal ...
Manufactured by:Genenta Science based inMilano, ITALY
After apheresis collection, a functional copy of the therapeutic gene is inserted into the patient’s own HSPCs using a non-replicating lentiviral vector. This is an ex-vivo process called transduction. We believe that LVVs are the first choice for ex-vivo gene therapy in humans because they can efficiently transduce HSPCs with potentially large transgenes that will allow us to expand ...
by:Neurona Therapeutics based inSouth San Francisco, CALIFORNIA (USA)
A wholly-owned pipeline of novel cell therapy products. Neurona is developing allogeneic, off-the-shelf neural cell therapies for multiple chronic neurological disorders. The pipeline includes neuronal, glial, and gene-edited cell therapy candidates led by NRTX-1001, a first-in-class inhibitory neuron ...