- Home
- Equipment
- united kingdom
- t cell subtypes from naive t cells
Show results for
Refine by
T Cell Subtypes From Naive T Cells Equipment Supplied In United Kingdom
51 equipment items found
Manufactured by:Treos Bio Limited based inLondon, UNITED KINGDOM
At TREOS we discovered that an individual’s HLA genotype is the main determinant of immune responses. This breakthrough led to the development of the PEPI Test (CE Marked) that predicts peptide-specific T cell responses of HLA genotyped individuals. Based on the PEPI Test we have been co-developing with each PolyPEPI™ product a Companion Diagnostic to predict likely responders and ...
Manufactured by:TC BioPharm based inHolytown, UNITED KINGDOM
TCB007 is an unmodified allogeneic gamma delta T cell product, being used for the treatment of COVID-19. This product is at the CTA application stage and is expected to enter phase 1 trials in summer 2020. ...
Manufactured by:Takeda Pharmaceutical Company Limited based inChuo-ku, JAPAN
Brentuximab vedotin (brand name: Adcetris) is a treatment for post-transplant consolidation, relapsed or refractory Hodgkin lymphoma (cancer of the lymphatic system distinguished by the presence of CD30-positive Reed-Sternberg cells), and systemic anaplastic large cell lymphoma (a type of aggressive T-cell ...
Manufactured by:Oxford Vacmedix UK Limited based inOxford, UNITED KINGDOM
In the image below the Recombinant Overlapping Peptide is the “Antigen” being presented to the T Cell Receptor (TCR). This then triggers the growth of T Cells that will recognise the same marker on cancer cells leading to their destruction. ...
Manufactured by:ProImmune Ltd. based inOxford, UNITED KINGDOM
Human MR1 Tetramers detect MAIT cells with human MR1 tetramers. ProImmune is the leading commercial source worldwide for fluorescently labeled human MR1 tetramers. MR1 complexes bind to T cell receptors on mucosal-associated invariant T (MAIT) cells. MAIT cells have a particular specificity (as determined by the relevant MR1-binding small molecule ligand used), allowing identification, ...
Manufactured by:Adaptimmune LLC based inPhiladelphia, PENNSYLVANIA (USA)
Our ADP-A2M4 (MAGE-A4) SPEAR T-cell therapy is directed to a member of the MAGE family of cancer testis antigen expressed in a number of solid tumor cell types. The MAGE- A4 antigen is among the most commonly expressed cancer-testis antigens. We are conducting various trials with the ADP-A2M4 SPEAR T-cell in various solid ...
Manufactured by:Adaptimmune LLC based inPhiladelphia, PENNSYLVANIA (USA)
Our ADP-A2M10 (MAGE-A10) T-cell therapy is directed to a member of the MAGE family of cancer testis antigens expressed in a number of solid tumor cell types. Any expression in cancer is often associated with higher grade tumors. Please note that the two trials with ADP-A2M10 are now closed for ...
Manufactured by:Adaptimmune LLC based inPhiladelphia, PENNSYLVANIA (USA)
Our ADP-A2AFP SPEAR T-cell product targets alpha-fetoprotein (AFP) is being investigated in an ongoing Phase 1 clinical trial for the treatment of patients with hepatocellular carcinoma (liver ...
Manufactured by:ProImmune Ltd. based inOxford, UNITED KINGDOM
ProM1™ MHC Class I Monomers, biotin labeled enabling specialist assays for defined MHC Class I peptide target ...
Manufactured by:Adaptimmune LLC based inPhiladelphia, PENNSYLVANIA (USA)
Our ADP-A2M4CD8 SPEAR T-cell therapy is our first "next-generation" therapy and is directed to MAGE-A4, a member of the MAGE family of cancer-testis antigens expressed in a number of solid tumor types. What differentiates this therapy from our ADP-A2M4 SPEAR T-cells is that these cells also express the CD8α co-receptor alongside the engineered TCR that targets MAGE-A4. Preclinical data ...
Manufactured by:TC BioPharm based inHolytown, UNITED KINGDOM
At TC BioPharm, we apply chimeric antigen receptor T cell (CAR-T) technology to gamma delta T (GDT) cells. This takes advantage of the endogenous gamma delta T cell receptor (TCR), and combines it with chimeric antigen receptors. This involves adding a transgene to the GDT cells which encodes for a truncated version of a conventional CAR, one which doesn’t contain a CD3ζ activating ...
Manufactured by:Omega Diagnostics Group PLC based inAlva, UNITED KINGDOM
VISITECT® CD4 Advanced Disease supports the identification of advanced disease in people living with HIV. VISITECT® CD4 Advanced Disease is a unique, instrument-free, rapid and disposable CD4 test benefiting patients and healthcare ...
Manufactured by:TC BioPharm based inHolytown, UNITED KINGDOM
TCB002 is an unmodified allogeneic gamma delta T cell product, being initially used for the treatment of Acute Myeloid Leukaemia (AML). This product is currently undergoing a phase 1 clinical trial as part of a dose escalation and safety study, in partnership with ÚKHT, Institute of Hematology and Blood Transfusion, Prague. AML is a cancer characterized by infiltration of the bone marrow, ...
Manufactured by:PsiOxus Therapeutics Ltd. based inAbingdon, UNITED KINGDOM
Three transgenes: Producing membrane bound CD80 and secreted MIP1α and IFNa. As part of our expanding T-SIGn platform pipeline, this candidate is progressing through its IND enabling activities in readiness for entering clinical ...
Manufactured by:PsiOxus Therapeutics Ltd. based inAbingdon, UNITED KINGDOM
Three transgenes: Producing IL-12, IL-15 and a chemokine. As part of our expanding T-SIGn platform pipeline, this candidate is progressing through its IND enabling activities in readiness for entering clinical ...
Manufactured by:PsiOxus Therapeutics Ltd. based inAbingdon, UNITED KINGDOM
Novel transgene combinations. Our research team are developing a suite of viral vectors with new and innovative transgene ...
Manufactured by:Oxford Vacmedix UK Limited based inOxford, UNITED KINGDOM
Tumours can often avoid being targeted by these T Cells by looking like a cell found normally in the body often referred to as “self”. If a group of T Cells can be encouraged to recognise these tumours as foreign and not self then they will attack the tumour and provide an effective treatment against it. Injecting a preparation that stimulates these T Cells effectively vaccinates the ...
Manufactured by:TC BioPharm based inHolytown, UNITED KINGDOM
TC BioPharm’s cell banks have been developed as a resource for clinical development of cost-effective, safe and efficacious therapeutic treatments and ultimately, the ability to treat more patients. These T cell banks provide TC BioPharm with core technology to develop a deep portfolio of next-generation CAR-T products directed against a wide variety of different infectious diseases such as ...
Manufactured by:Treos Bio Limited based inLondon, UNITED KINGDOM
Off-the-shelf products contain 6-12 shared tumor-specific antigen derived peptides optimized for a population. They are personalized with a candidate companion diagnostic test (CDx). In silico trials predicted that these peptides induce exceptionally broad T cell responses against at least 3 tumor-specific antigens in high proportion of patients, without need of biopsy. Phase 1 clinical study ...
Manufactured by:Biosceptre International Limited based inCambridge, UNITED KINGDOM
CAR T-cell therapy is the engineering of a patient’s T cells, a type of white blood cell. A small portion of these cells are collected, from a patient’s blood sample, and re-engineered to produce chimeric antigen receptors (CAR’s) on the cell surface. The chimeric antigen receptors give T cells the ability to target cancer cells. They comprise two specific components: one, an ...