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T Cell Subtypes From Naive T Cells Equipment Supplied In Europe
136 equipment items found
Manufactured by:Treos Bio Limited based inLondon, UNITED KINGDOM
At TREOS we discovered that an individual’s HLA genotype is the main determinant of immune responses. This breakthrough led to the development of the PEPI Test (CE Marked) that predicts peptide-specific T cell responses of HLA genotyped individuals. Based on the PEPI Test we have been co-developing with each PolyPEPI™ product a Companion Diagnostic to predict likely responders and ...
Manufactured by:Santa Cruz Biotechnology, Inc. based inDallas, TEXAS (USA)
Concanamycin A is a specific inhibitor of vacuolar type H+-ATPase activity (V-ATPase) and is capable of inducing ...
Manufactured by:Ardigen based inKraków, POLAND
Accelerate discovery and improve safety of TCR therapies using Artificial Intelligence. Following the unique opportunity for curing patients provided by the development of cell therapies (e.g. TCR discovery), Ardigen has set on the path to advance the field with its Artificial Intelligence platform. Many challenges stand in the way of successful therapy discovery and development. Let us know how ...
Manufactured by:TC BioPharm based inHolytown, UNITED KINGDOM
TCB007 is an unmodified allogeneic gamma delta T cell product, being used for the treatment of COVID-19. This product is at the CTA application stage and is expected to enter phase 1 trials in summer 2020. ...
Manufactured by:Immudex ApS based inVirum, DENMARK
dCODE Dextramer technology enables the analysis of antigen-specific T cells by NGS or single-cell multi-omics. dCODE Dextramer adds a unique DNA barcode to the MHC Dextramer® reagent to detect antigen-specific T cells by NGS or single-cell multi-omics. High-avidity binding to T-cell receptors thanks to multiple MHC-peptide complexes. High-throughput screening with a unique barcode for each ...
by:Genmab A/S based inCopenhagen V, DENMARK
DuoBody-CD40x4-1BB (GEN1042) is a proprietary bispecific antibody, jointly owned by Genmab and BioNTech, created using Genmab’s DuoBody® technology. It is being co-developed under an agreement in which the companies share all costs and future profits for the product on a 50:50 basis. CD40 and 4-1BB were selected as targets to enhance both dendritic cells (DC) and antigen-dependent ...
Manufactured by:Takeda Pharmaceutical Company Limited based inChuo-ku, JAPAN
Brentuximab vedotin (brand name: Adcetris) is a treatment for post-transplant consolidation, relapsed or refractory Hodgkin lymphoma (cancer of the lymphatic system distinguished by the presence of CD30-positive Reed-Sternberg cells), and systemic anaplastic large cell lymphoma (a type of aggressive T-cell ...
by:BlueSky Immunotherapies GmbH based inWien, AUSTRIA
The high level of interferon induced by the delNS vector activates immunological defence reactions against cancer. It also stimulates the production of antiviral ...
by:Astraveus based inParis, FRANCE
In healthy patients T cells detect and kill sick cells. Cancer cells escape T cells recognition thanks to mutations. CAR-T cells (T cells equipped with a Chimeric Antigen Receptor) are artificially hardcoded to recognize and kill cancer cells. Multiple CAR-T therapies are commercially available but their access is limited by low manufacturing throughput and high prices. We use our exclusive ...
by:Engine Gmbh based inHennigsdorf, GERMANY
The UniPEx protein expression library consists of 2 Arrays representing clones in 2 different modified vectors. In total, more than 100,000 sequenced clones from different protein expression libraries (human fetal brain, T-cells, lung) were analysed in depth for their coding potential. After in-frame analysis only clones with a confirmed in-frame ORF were selected and redundancy with respect to ...
by:Horizon Therapeutics plc based inSaint Kevin`s, IRELAND
A fusion protein binding CD40L on T cells, blocking their interaction with CD40-expressing B cells. We are investigating dazodalibep in focal segmental glomerulosclerosis as well as conducting Phase 2 trials in kidney transplant rejection, rheumatoid arthritis and Sjögren’s ...
Manufactured by:Oxford Vacmedix UK Limited based inOxford, UNITED KINGDOM
In the image below the Recombinant Overlapping Peptide is the “Antigen” being presented to the T Cell Receptor (TCR). This then triggers the growth of T Cells that will recognise the same marker on cancer cells leading to their destruction. ...
Manufactured by:ProImmune Ltd. based inOxford, UNITED KINGDOM
Human MR1 Tetramers detect MAIT cells with human MR1 tetramers. ProImmune is the leading commercial source worldwide for fluorescently labeled human MR1 tetramers. MR1 complexes bind to T cell receptors on mucosal-associated invariant T (MAIT) cells. MAIT cells have a particular specificity (as determined by the relevant MR1-binding small molecule ligand used), allowing identification, ...
Manufactured by:Immatics N.V. based inTuebingen, GERMANY
Immatics’ TCER molecules can be produced and purified utilizing established processes to manufacture ...
Manufactured by:Adaptimmune LLC based inPhiladelphia, PENNSYLVANIA (USA)
Our ADP-A2M4 (MAGE-A4) SPEAR T-cell therapy is directed to a member of the MAGE family of cancer testis antigen expressed in a number of solid tumor cell types. The MAGE- A4 antigen is among the most commonly expressed cancer-testis antigens. We are conducting various trials with the ADP-A2M4 SPEAR T-cell in various solid ...
Manufactured by:Adaptimmune LLC based inPhiladelphia, PENNSYLVANIA (USA)
Our ADP-A2M10 (MAGE-A10) T-cell therapy is directed to a member of the MAGE family of cancer testis antigens expressed in a number of solid tumor cell types. Any expression in cancer is often associated with higher grade tumors. Please note that the two trials with ADP-A2M10 are now closed for ...
Manufactured by:Adaptimmune LLC based inPhiladelphia, PENNSYLVANIA (USA)
Our ADP-A2AFP SPEAR T-cell product targets alpha-fetoprotein (AFP) is being investigated in an ongoing Phase 1 clinical trial for the treatment of patients with hepatocellular carcinoma (liver ...
Manufactured by:Kiadis Pharma NV based inAmsterdam, NETHERLANDS
Accessing a new repertoire of targets. Two classes of molecule with therapeutic potential that are not currently addressed by antibody drugs are G-protein-coupled receptors and ion channels, largely because they display small epitopes not accessible to traditional antibodies and their sequence is often conserved and thus less likely to be ...
Manufactured by:Sartorius CellGenix GmbH based inFreiburg, GERMANY
CellGenix TCM is optimized for serum-free expansion and cultivation of T cells. It has been optimized and verified with CAR T cell protocols. In addition, it supports expansion of other cell types such as Treg and iNKT cells. We offer the cytokines and growth-factors needed for optimal growth separately. This gives you the freedom to customize and create your own optimal cytokine mixture. ...
by:Diasorin based inSALUGGIA, ITALY
DiaSorin strives to improve health-care around the globe through the development of innovative diagnostic solutions that can lead to better patient outcomes and provide economic benefits to the healthcare system. Thanks to its team of dedicated scientists, DiaSorin has developed a new concept assay to maximize EARLY Lyme borreliosis detection through a unique combination of humoral and cell ...