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Targeted Boron Drugs Equipment Supplied In Usa
92 equipment items found
by:TAE Life Sciences (TLS) based inFoothill Ranch, CALIFORNIA (USA)
TAE Life Sciences is committed to developing a portfolio of novel targeted boron drugs to expand the application of BNCT to other cancer types and to provide even better outcomes for indications historically treated with Boronophenylalanine (BPA), a boron delivery ...
Manufactured by:OPKO Health, Inc. based inMiami, FLORIDA (USA)
In our Natural Antisense Transcripts Antagonist (AntagoNAT) technology, an oligonucleotide molecule is designed to interfere with regulatory gene expression in order to enhance production of endogenous functional proteins. This strategy is unique and contrasts with established approaches which down-regulate protein production. This platform can lead to the discovery of new drugs to target ...
Manufactured by:Advanced Accelerator Applications SA based inRueil-Malmaison Cedex, FRANCE
AAA brand names for [18F]-choline (FCH). ...
Manufactured by:Advanced Accelerator Applications SA based inRueil-Malmaison Cedex, FRANCE
AAA brand names for 6-fluoro-[18F]-L-DOPA, a DOPA analog. Neurology, ...
by:DEARGEN Inc. based inDaejeon, SOUTH KOREA
Agonist refers to substances that activate a specific target protein. It can easily be viewed as the opposite of inhibitor. Until now, Deargen's drug-target interaction (DTI) was predicted based on the binding affinity between the substance and the target protein, which causes barrier to distinguish between the inhibition and activation activity. In addition, the demand for agonist hit discovery ...
Manufactured by:Symberix, Inc. based inDurham, NORTH CAROLINA (USA)
Trillions of microorganisms colonize the human body and play a central role in health and disease. Symbiotic drugs target bacteria to improve human health while leaving good microbes ...
by:Zymeworks Inc based inVancouver, BRITISH COLUMBIA (CANADA)
ZW49 is a HER2-targeted antibody drug conjugate (ADC) developed using Zymeworks’ proprietary Azymetric™ and ZymeLink™ platforms. ZW49 is currently being evaluated in a Phase 1 clinical trial as a treatment for patients with locally advanced or metastatic HER2-expressing cancers that have progressed following treatment with existing approved therapies, including HER2-targeted ...
Manufactured by:Kala Pharmaceuticals, Inc. based inArlington, MASSACHUSETTS (USA)
AMPPLIFY Drug Delivery Technology is designed to enhance penetration through the mucus barrier and deliver increased concentration of drug to the target ocular tissue. AMPPLIFY Drug Delivery Technology has been shown to improve delivery of loteprednol etabonate compared to traditional suspension eyedrops without ...
Manufactured by:Verge Genomics based inSouth San Francisco, CALIFORNIA (USA)
The breadth and depth of our pipeline demonstrates the power of the ConVERGEMplatform. All pipeline programs have been discovered and developed on our proprietary platform. ...
Manufactured by:Concept Medical Inc. based inTampa, FLORIDA (USA)
Conversion of Sirolimus drug into sub-micron sized particles; Nanocarriers created by encapsulation of sub-micron sized Sirolimus drug into highly biocompatible drug Carrier-phospholipid; Upon inflation of MagicTouch SCB at target site, nanocarriers with Sirolimus drug inside gets transferred to the vessel wall following the principle of co-efficient diffusion; Upon body pH variation, ...
Manufactured by:CytomX Therapeutics, Inc. based inSouth San Francisco, CALIFORNIA (USA)
CytomX is developing CX-2009, a Probody drug conjugate (PDC) conjugated with DM4, a highly potent cytotoxic drug, targeting CD166, also known as ALCAM. CD166 is a molecule widely and highly expressed on solid tumor cells and previously considered “undruggable” given its expression on normal tissues. In preclinical studies, Probody drug conjugates targeting CD166, have led to ...
by:DEARGEN Inc. based inDaejeon, SOUTH KOREA
DearDTI presents drug candidates with a good efficacy by predicting the binding affinity, based on information about the compound-protein ...
Manufactured by:Addex Therapeutics based inGeneva, SWITZERLAND
Allosteric modulators are an emerging class of orally available small molecule therapeutic agents that may offer a competitive advantage over classical ...
Manufactured by:Lexogen GmbH based inVienna, AUSTRIA
SLAMseq is a high-sensitivity method for time-resolved measurement of newly synthesized and existing RNA in cultured cells. SLAMseq enables resolution of RNA synthesis and degradation kinetics. Lexogen offers a family of kits based on the new SLAMseq method: Thiol (SH)-Linked Alkylation for the Metabolic sequencing of RNA. SLAMseq enables the identification and quantification of newly synthesized ...
by:Da Zen Theranostics, Inc. based inSilicon Valley, CALIFORNIA (USA)
Circumventing drug toxicity and drug resistance is key to effective anticancer therapy. Da Zen’s products and technologies deliver targeted anticancer drugs, such as simvastatin and cisplatin conjugated to a cancer targeting dye-carrier, exclusively to cancer cells, with the drugs confined to the cancer cells for much longer than current therapies (up to three to four weeks) and no evidence ...
Manufactured by:Surmodics, Inc. based inEden Prairie, MINNESOTA (USA)
The Surmodics drug-delivery coatings utilize innovative technology to meet a variety of clinical needs – from short-term to long-term controlled release – and across a range of compounds including small molecules and antibiotics. Our unique Bravo™ durable drug-delivery polymer system is designed for site-specific delivery and stability of low molecular weight ...
Manufactured by:Base4 based inChicago, ILLINOIS (USA)
Leading the RNA ensemble revolution. Exploiting RNA dynamics: RNAs rapidly exchange between a vast array of distinct 3D conformations, each revealing potentially novel binding surfaces. These dynamics are critical to understanding RNA function and fully exploiting its untapped drug potential. Our proprietary platform is built on unparalleled advancements in RNA structural biology that allows for ...
Manufactured by:Bio-Rad Laboratories, Inc. (Antibodies) based inHercules, CALIFORNIA (USA)
Antibodies for bioanalysis and drug monitoring of adalimumab and biosimilars. Develop highly selective and sensitive PK and ADA assays for adalimumab (Humira) using our range of ready-made anti-idiotypic antibodies. Highly specific to adalimumab or the adalimumab-TNFα complex. Fully human surrogate positive control or calibrator. Sequence defined, well characterized reagents with secure ...
by:TAE Life Sciences (TLS) based inFoothill Ranch, CALIFORNIA (USA)
Gordon Locher first proposed Boron Neutron Capture Therapy (BNCT) in 1936. Clinical investigation and treatments were first introduced in the USA in the 1950s and showed promising results. Historically, BNCT clinical studies have been carried out using boronophenylalanine (BPA) and neutrons derived from the core of a nuclear reactor. While the clinical outcomes have been encouraging, the ...
Manufactured by:SEngine Precision Medicine based inSeattle, WASHINGTON (USA)
Guiding drug discovery with proprietary high throughput 3D patient cell technology and genomics will drastically increase the success of novel drug candidates and directly result in faster development at reduced costs. SEngine Precision Medicine’s innovative approach brings diagnostics, drug discovery and proprietary algorithms together with our patient-derived 3D tumor organoids to ...