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  • Software Solutions for Deep Mutational Scanning & Selection
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Testing Services Targeting To Preclinical Studies Equipment Supplied In Usa Washington

12 equipment items found
In WashingtonAvailable In WashingtonNear Washington

EMulate - Indolor Therapeutics

EMulate - Indolor Therapeutics

Manufactured by:EMulate Therapeutics, Inc.   based inBellevue, WASHINGTON (USA)
Indolor Therapeutics is feasibility (phase I) trial ready for the treatment of acute and chronic pain by the application of specific pain-managing ulRFE fields, another expression of EMulate’s Therapeutic ...
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Icosavax - Model IVX-121 - RSV VLP Vaccine Candidate

Icosavax - Model IVX-121 - RSV VLP Vaccine Candidate

Manufactured by:AstraZeneca   based inCambridge, UNITED KINGDOM
IVX-121 targets respiratory syncytial virus (RSV), a major cause of viral pneumonia for which no vaccine has been FDA approved. IVX-121 incorporates a stabilized prefusion F antigen licensed from NIAID/NIH (DS-Cav1; Science 2019). RSV F is known to undergo major structural changes that allow viral entry into the host cell, and during that process, critical protective epitopes are lost. Protein ...
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Cerevast - Microsphere-Mediated Ophthalmic Ultrasound

Cerevast - Microsphere-Mediated Ophthalmic Ultrasound

Manufactured by:Cerevast Medical, Inc.   based inBothell, WASHINGTON (USA)
Microsphere-mediated ultrasound represents a new treatment modality for RVO that addresses the underlying cause of the condition. Cerevast’s microspheres have a mean diameter of 1.1 – 3.3 microns and are comprised of a lipid shell and gas core. These microspheres can pass through the retinal vasculature due to their small size. Concomitantly administering ophthalmic ultrasound induces ...
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ADAPTIR-FLEX - Technology

ADAPTIR-FLEX - Technology

Manufactured by:Aptevo Therapeutics   based inSeattle, WASHINGTON (USA)
ADAPTIR-FLEX technology extends advantages of ADAPTIR technology to create protein therapeutics with varied specificity and valency and potentially new modes of ...
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ADAPTIR - Modular and Flexible Technology

ADAPTIR - Modular and Flexible Technology

Manufactured by:Aptevo Therapeutics   based inSeattle, WASHINGTON (USA)
Demonstrated ability to produce monospecific and bispecific drug candidates; Leverages IgG1 Fc to form homodimeric bispecific molecules; IgG1-derived Fc can be mutated to ablate effector functions antibody-dependent cellcytotoxicity (ADCC) and complementdependent cytotoxicity (CDC), while maintaining original stability and half-life (confirmed by cell binding, cell function, SPRbased measurements ...
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Cyrus - Novel IL-2 Autoimmunity Technology

Cyrus - Novel IL-2 Autoimmunity Technology

by:Cyrus Biotechnology Inc.   based inSeattle, WASHINGTON (USA)
Novel IL-2 approaches and technologies are driving innovation in the therapeutic development space. The IL-2 pathway influences critical aspects of both immune stimulation and immune regulation, through the development and expansion of regulatory T cells ...
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IASIS - Broad Spectrum Antiseptics for Wound Healing and Medical Device Coatings

IASIS - Broad Spectrum Antiseptics for Wound Healing and Medical Device Coatings

Manufactured by:Iasis Molecular Science   based inSpokane, WASHINGTON (USA)
Our platform No. 1 antiseptics are a family of novel silver-based complexes for the treatment of wound infections and for use as the active component of antimicrobial medical device coatings. These antiseptics offer excellent potency against drug-resistant pathogens, little concern of selection for resistance, lower cellular toxicity, and process benefits not found with commercial antiseptics. ...
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Icosavax - Model IVX-A12 - RSV/hMPV Bivalent VLP Vaccine Candidate

Icosavax - Model IVX-A12 - RSV/hMPV Bivalent VLP Vaccine Candidate

Manufactured by:AstraZeneca   based inCambridge, UNITED KINGDOM
IVX-A12 is a bivalent combination of IVX-121 and IVX-241, a human metapneumovirus (hMPV) VLP vaccine candidate. IVX-A12 is being designed to target both RSV and hMPV in a single vaccine candidate. hMPV is being increasingly recognized as a major contributor to acute respiratory infection and pneumonia with rates of pneumonia (Clinics in Chest Medicine 2017) and hospitalization (JID 2012) similar ...
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Mantarray - 3D Tissue Contractility Analysis

Mantarray - 3D Tissue Contractility Analysis

Manufactured by:Curi Bio   based inSeattle, WASHINGTON (USA)
Mantarray is Curi’s Platform for Human-Relevant 3D Engineered Muscle Tissue Analysis. Get Clinically-relevant Functional Data with 3D Tissues. Mantarray brings functional data into the earliest stages of preclinical testing of new medicines. By providing parallel analysis of 3D engineered muscle tissues with adult-like functional profiles, Mantarray enables the discovery, safety, and ...
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AGC Biologics - Lenti and Retro Viral Vectors

AGC Biologics - Lenti and Retro Viral Vectors

Manufactured by:AGC Biologics   based inBothell, WASHINGTON (USA)
AGC Biologics develops and manufactures Lenti and Retro viral vectors. Our ready-to-use platform capabilities are built on cell factories (up to 48L) and bioreactors (up to 200L) using adherent processes, designed entirely in-house. Our quality systems, GMP manufacturing scale and regulatory qualification allow us to meet both clinical and commercial demand. Moreover, our scale down ...
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microMend - Wound Closure Device

microMend - Wound Closure Device

Manufactured by:KitoTech Medical, Inc.   based inSeattle, WASHINGTON (USA)
Experience a new wound closure device that is as effective as sutures and as fast and easy to apply as a bandage. It delivers superior clinical results and improved patient experience while reducing procedure ...
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Aptevo - Model APVO436 (anti-CD123 x anti-CD3) - Optimized ADAPTIR Bispecific Antibody

Aptevo - Model APVO436 (anti-CD123 x anti-CD3) - Optimized ADAPTIR Bispecific Antibody

Manufactured by:Aptevo Therapeutics   based inSeattle, WASHINGTON (USA)
APVO436 is an optimized ADAPTIR bispecific antibody candidate designed to redirect T-cell cytotoxicity through the dual targeting of CD3, a T-cell co-receptor that promotes cytotoxicity, and CD123, a cell surface receptor highly expressed in several hematological malignancies, including acute myeloid leukemia, acute lymphoblastic leukemia, hairy cell leukemia, myelodysplastic syndrome, and ...
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