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- Acute Kidney Injury (AKI) Device for Reduction of Galectin-3 Levels
- Acute Kidney Injury (AKI) Device for Plasmapheresis Therapy
- Acute Kidney Injury (AKI) Device for Patient Selective Apheresis
- Microbiome Therapeutics for Clinical Trials
- Medical solutions for MiniTC and mini-stem system sector
- Software Solutions for Deep Mutational Scanning & Selection
- Software Solutions for COVID-19
Therapeutics Development Equipment Supplied In North America
46 equipment items found
Manufactured by:ASC Therapeutics based inMilpitas, CALIFORNIA (USA)
Genome editing technologies enables permanent modifications to the genome by harnessing the activities of certain enzymes (e.g. nucleases and integrase) and invoking DNA repair mechanisms at specific locations in the genome. As a therapeutic modality, genome editing can correct a defective gene, disrupt a deleterious gene, or target a therapeutic gene to a ...
by:Cyrus Biotechnology Inc. based inSeattle, WASHINGTON (USA)
Novel IL-2 approaches and technologies are driving innovation in the therapeutic development space. The IL-2 pathway influences critical aspects of both immune stimulation and immune regulation, through the development and expansion of regulatory T cells ...
by:Neoclease based inBoston, MASSACHUSETTS (USA)
Neoclease is pioneering the future of precision medicine through advanced technology in synthetic biology and generative AI. By developing synthetic nucleases, the company enhances gene editing processes to achieve unprecedented specificity and efficacy. These enzymes are meticulously crafted using proprietary algorithms powered by state-of-the-art GPT neural networks, which are ...
by:Caribou Biosciences, Inc. based inBerkeley, CALIFORNIA (USA)
Natural killer (NK) cells, as their name implies, play an important role in ridding the body of cancer and viruses. NK cells are emerging as an increasingly important cell type for therapeutic development. Solid tumors are particularly challenging to treat and CAR-T cells have largely underperformed in the solid tumor setting. NK cells, however, inherently ...
Manufactured by:Genscript based inPiscataway, NEW JERSEY (USA)
cPass Neutralization Antibody Detection kit detects circulating neutralizing antibodies against SARS-CoV-2 that block the interaction between the receptor binding domain (RBD) of the viral spike glycoprotein with the ACE2 cell surface receptor. This kit would be instrumental in vaccine and therapeutic development as it is suitable for all antibody isotypes and ...
Manufactured by:Realize Therapeutics Corp. based inLake Bluff, ILLINOIS (USA)
SIBO is a condition related to excess numbers of bacteria in the small intestine, and can be linked to Irritable Bowel Syndrome, Research clearly shows that certain microbes are very effective at treating SIBO and related issues. Realize Therapeutics is developing formulas to address these health ...
Manufactured by:Entero Therapeutics, Inc. based inBoca Raton, FLORIDA (USA)
Capeserod is a selective 5-HT4 receptor partial agonist, which Entero Therapeutics is repurposing and developing for multiple GI conditions. Based on the biological evidence of expression of 5-HT4b receptor subtype in human GI tract, Entero Therapeutics believes that capeserod may directly or indirectly initiate the peristaltic or secretory ...
Manufactured by:ProImmune Ltd. based inOxford, UNITED KINGDOM
Detecting and targeting specific MHC-peptide complexes is of material interest for understanding many disease conditions better and for developing novel therapeutic interventions. It has been very challenging to develop antibodies that bind selectively to an MHC-peptide combination over a more general MHC ...
Manufactured by:Neutron Therapeutics, Inc. based inDanvers, MASSACHUSETTS (USA)
Neutron Therapeutics has developed an accelerator-based, in-hospital neutron source to replace the previously required nuclear reactor. This source is composed of a 2.6 MeV electrostatic proton accelerator and a rotating, solid lithium target for generating neutrons. Neutron Therapeutics will provide this neutron source as part of a comprehensive ...
Manufactured by:Great Lakes NeuroTechnologies based inCleveland, OHIO (USA)
By integrating advanced technology with patient-centered design, KinesiaU™ provides objective assessments that can improve clinical outcomes by identifying optimal therapeutic activities. The development of this system by Great Lakes NeuroTechnologies emphasizes a commitment to advancing neurological ...
by:Sword Diagnostics, Inc. based inCarmel, INDIANA (USA)
Utilizing our proprietary Sword Swift™ Method Development Process and Sword Swift™ Detection Reagents, our scientists can develop sensitive quantitative assays to measure the amounts of free or bound drug in preclinical or clinical samples with high accuracy and ...
by:DxDiscovery, Inc. based inReno, NEVADA (USA)
Production of monoclonal antibodies (mAbs) is central to all efforts at DxDiscovery. MAb production begins with immunization of a mouse with an antigen. Several weeks after immunization, spleen cells are harvested. B cells in the spleen produce antibody but cannot grow in culture. The spleen cells are fused with cells of a myeloma line. The myeloma cells cannot produce antibody, but they will ...
Manufactured by:Jointechlabs Inc. based inNorth Barrington, ILLINOIS (USA)
Based on our platform and technology, Jointechlabs is developing therapies for unmet medical needs. Our first therapeutic in clinical development JTL-T-01 is a proprietary injectable stem cell scaffold as a biologic therapy for osteoarthritis, for approval under the FDA’s fast-track program. ...
by:Sword Diagnostics, Inc. based inCarmel, INDIANA (USA)
Sword scientists specialize in the development of qualitative or quantitative bioanalytical methods that measure cellular biomolecules active in a specific disease state. Cell-based assays are bioanalytical methods that measure the presence, amount, or activity of biomolecules in cells, cell fractions, nuclear extracts, tissue extracts, or cell extracts. In pharmaceutical drug ...
Manufactured by:Xenobiotic Detection Systems International, Inc. based inDurham, NORTH CAROLINA (USA)
The AhR also has been shown to play a key regulatory role in endogenous physiological responses as well as human disease and it has become an important new target for the development of therapeutic chemicals. Since the AhR can be activated/inhibited by a broad range of structurally diverse natural and synthetic chemicals, high-throughput AhR-responsive cell-based ...
by:Sutro Biopharma Inc. based inSouth San Francisco, CALIFORNIA (USA)
Conventional methods for expressing proteins utilize cell lines originating from bacteria, yeast, insects, plants, or mammals. Because these methods require intact, functioning cells, the biochemical and biophysical parameters under which proteins are produced using these methods are inherently limited, often failing to produce many proteins and biologics. Using cell-based expression systems to ...
Manufactured by:Catalent, Inc based inSomerset, NEW JERSEY (USA)
GPEx cell line development technology is a proven technology that generates high-performance, highly stable, production cell lines. Virtually any cDNA (mAb and multigenic applications) can be inserted into cells. To date, over 600 different mAb and mAb fusions and over 160+ different recombinant proteins have been produced using the GPEx system, with 160+ clinical trials ...
by:AbCellera Biologics Inc. based inVancouver, BRITISH COLUMBIA (CANADA)
We search, decode, and analyze natural immune systems to find antibodies that our partners can develop into drugs that improve ...
Manufactured by:Eliaz Therapeutics based inSanta Rosa, CALIFORNIA (USA)
Acute Kidney Injury (AKI) and sepsis are major public health concerns, with high incidence, mortality and morbidity. Despite efforts to develop new interventions, current therapeutic options are limited in scope and effectiveness. At Eliaz Therapeutics, we have developed a patented, unique medical device that will remove ...
Manufactured by:Kalaris based inWaltham, MASSACHUSETTS (USA)
Kalaris Therapeutics is focused on developing innovative treatments for retinal diseases, aiming to reduce the burden of frequent clinical visits for patients with retinal neovascular and exudative conditions. Their lead product, TH103, is a fully humanized, recombinant fusion protein designed for intravitreal delivery as an anti-VEGF agent. ...