Model SORT-C01 - pLV-H1TetO-GFP-Puro

Inducible pLV-RNAi vector system is designed to deliver gene silencing in a tightly regulated fashion in mammalian cell lines. The shRNA expression is suppressed by Tet repressor (TetR) binding to the hybrid H1 promoter containing tetracycline operators (TetO) and RNA interference only takes place in the presence of tetracycline. The inducible RNAi system provides the option of expressing shRNA in certain period of time.