Refine by
Lentiviral Vector Equipment & Supplies
15 equipment items found
Manufactured by:Cellomics Technology, LLC based inHalethorpe, MARYLAND (USA)
Lentiviral vector-CAG, BSD contains Multiple Cloning Sites (MCS) downstream of the CAG promoter, and blasticidin driven by the PGK promoter as a selection marker. Clone your gene of interest into the MCS, then co-transfect with EZ-LentiPACK Packaging System into packaging cells, such as HEK293T to produce VSV-G pseudotyped lentivirus. ...
Manufactured by:Rocket Pharmaceuticals, Inc. based inCranbury, NEW JERSEY (USA)
The process involves collection and isolation of a patient’s hematopoietic stem cells (HSCs), insertion of the corrected gene into the HSCs via a lentiviral vector outside the body, and the infusion of modified HSCs back into the patient. The goal is to enable sufficient quantities of a healthy, disease-modifying therapeutic protein to be manufactured by ...
Manufactured by:Cellomics Technology, LLC based inHalethorpe, MARYLAND (USA)
Lentiviral vector transduction is a powerful tool for delivering target genes into almost all types of dividing and non-dividing mammalian cells. Lentiviral vector can stably integrate into the host genome, allowing long-term stably, high-level gene expression both in vitro and in vivo. ...
Manufactured by:Genenta Science based inMilano, ITALY
After apheresis collection, a functional copy of the therapeutic gene is inserted into the patient’s own HSPCs using a non-replicating lentiviral vector. This is an ex-vivo process called transduction. We believe that LVVs are the first choice for ex-vivo gene therapy in humans because they can efficiently transduce HSPCs with potentially large transgenes ...
Manufactured by:Aldevron, LLC based inFargo, NORTH DAKOTA (USA)
Aldevron provides pALD Lenti packaging plasmids through our partnership with OXGENE, who have optimized them for lentiviral vector production. They are immediately available at all quality levels, eliminating the need to manufacture custom batches. This reduces your costs and significantly reduces time to manufacture vectors for clinical ...
Manufactured by:Rocket Pharmaceuticals, Inc. based inCranbury, NEW JERSEY (USA)
The process involves collection and isolation of a patient’s hematopoietic stem cells (HSCs), insertion of the corrected gene into the HSCs via a lentiviral vector outside the body, and the infusion of modified HSCs back into the patient. The goal is to enable sufficient quantities of a healthy, disease-modifying therapeutic protein to be manufactured by ...
Manufactured by:Cellomics Technology, LLC based inHalethorpe, MARYLAND (USA)
Lentiviral packaging is the most critical step for generating high titer of lentivirus. EZ-LentiPACK is an optimized and ready-to use packaging system for the production of the highest titers of replication-incompetent ...
Manufactured by:Biosettia Inc. based inSan Diego, CALIFORNIA (USA)
Inducible pLV-RNAi vector system is designed to deliver gene silencing in a tightly regulated fashion in mammalian cell lines. The shRNA expression is suppressed by Tet repressor (TetR) binding to the hybrid H1 promoter containing tetracycline operators (TetO) and RNA interference only takes place in the presence of tetracycline. The inducible RNAi system provides the option of expressing shRNA ...
Manufactured by:Biosettia Inc. based inSan Diego, CALIFORNIA (USA)
Inducible pLV-RNAi vector system is designed to deliver gene silencing in a tightly regulated fashion in mammalian cell lines. The shRNA expression is suppressed by Tet repressor (TetR) binding to the hybrid H1 promoter containing tetracycline operators (TetO) and RNA interference only takes place in the presence of tetracycline. The inducible RNAi system provides the option of expressing shRNA ...
Manufactured by:OriGene Technologies, Inc. based inRockville, MARYLAND (USA)
OriGene offers pre-made lentiviral shRNA plasmid kits containing 4 sequence-verified expression cassettes that target your gene of interest. Each lentiviral cassette contains three major functional elements: shRNA, a puromycin selection marker & a tGFP reporter. With a guaranteed knockdown of ≥70%, these kits and our ready-to-use lenti-shRNA particles are a great option for studying ...
Manufactured by:DSS Takara Bio India Pvt Ltd based inNew Delhi, INDIA
Lenti-X SARS-CoV-2 Packaging Single Shots (Universal) gives you the flexibility to easily produce high-titer lentivirus pseudotyped with any SARS-CoV-2 spike variant desired. Simply clone any desired SARS-CoV-2 spike variant sequence into the provided expression vector, dilute in sterile water with your transfer vector of choice, and add to a tube of single shots. Then, apply the reconstituted ...
Manufactured by:Rocket Pharmaceuticals, Inc. based inCranbury, NEW JERSEY (USA)
FA is a rare, genetic disorder affecting DNA repair. Approximately two-thirds of FA cases are caused by genetic defects in the FANCA gene, which results in the FA subtype known as FA Complementation Group A (FA-A). FA patients may develop bone marrow failure (very low blood counts), cancers of the blood or other ...
Manufactured by:Rocket Pharmaceuticals, Inc. based inCranbury, NEW JERSEY (USA)
PKD is a rare, genetic blood disorder. PKD is caused by a defect in the PKLR gene which is responsible for energy production in red blood cells (RBCs). RBCs carry oxygen to the rest of the body. When the PKLR gene has a defect, RBCs are limited in their ability to produce energy and remain intact. As a result, patients with PKD frequently have anemia, chronic fatigue, yellowing of the skin and ...
Manufactured by:Rocket Pharmaceuticals, Inc. based inCranbury, NEW JERSEY (USA)
LAD-I is a rare genetic disorder affecting the immune system and is caused by a defect in the ITGB2 gene, leading to a deficiency in CD18. Due to this deficiency, white blood cells (primarily neutrophils) are unable to leave the bloodstream to go to the site of infection. As a result, patients with severe LAD-I can develop life-threatening infections which they are unable to fight. Without a ...
Manufactured by:Scarab Genomics, LLC based inMadison, WISCONSIN (USA)
Clean Genome® E. coli has eliminated inherent troublesome and unnecessary genes to create a production host that generates recombinant proteins and nucleic acids efficiently and continuously without compromising the product or the process. All strains are derived from the revolutionary MDS42 reduced genome strain described in Science 312:1044-6, and are further deleted to create ...