3D Computer-aided Antibody Structure Analysis Services
3D Computer-aided antibody structure analysis service based on advanced AI protein modeling software (AlphaFold) and antibody design expertise.
Servcies Overview
- The aggregation scan analysis on antibody 3D model (VH+VL) Aggregation potential is estimated from an analysis of antibody 3D surface patches from a combination of hydrophobic, electrostatic, and side chain accessibility areas.
- 3D PTM analysis The 3D PTM analysis includes the evaluation of disulfide bonds, deamidation, glycosylation, protease, and oxidation sites in addition to side chain accessibility.
- 3D B cell epitope, T cell epitope, MHC II epitope Analysis of potential T cell , B cell , MHC II and antigenicity epitopes in the framework of the antibody by using licensed software and in-house tools.
- Calculated pI of the antibody FV (VH+VL) The pI of the antibody is calculated, which is considered to be an indicator for developability.
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