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Antigen Specificity Services In North America
27 services found
Manufactured by:POP Biotechnologies, Inc. (POP BIO) based inBuffalo, NEW YORK (USA)
CoPoP enables liposomes to stably bind short MHC-I epitopes upon admixture. Better delivery of epitopes and adjuvants to immune cells in draining lymph nodes. Induce higher frequency of antigen specific CD8+ T cells with > 10,000X lower peptide ...
Manufactured by:MedGenome Inc. based inCounty of New Castle, DELAWARE (USA)
Hybridoma technology has been the forefront tool in generating monoclonal antibodies but is time consuming and costly. MedGenome’s proprietary HitMab platform now enables researchers to identify antigen-specific antibodies in less than 6 months’ ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
Monoclonal antibodies (mAbs) are monovalent proteins expressed by B cells, capable of precisely targeting 3D epitopes, which makes it a compelling therapeutic option. Over 70 monoclonal antibody drugs have received FDA approval. Monoclonal antibody drugs dramatically transform modern medicine by offering targeted treatments for a variety of diseases. These antibodies specifically activate immune ...
Manufactured by:MedGenome Inc. based inCounty of New Castle, DELAWARE (USA)
Utilizing targeted next-generation sequencing of these variable regions, can provide deeper insights into B-cell differentiation, BCR somatic hypermutation, class switching, and antigen specificity. Major applications of BCR repertoire profiling include diagnostic biomarker discovery, tracking known repertoire sequences and disease diagnosis. ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
To maintain the immune system's homeostasis, multiple control systems are essential for managing infections, inhibiting tumor growth, preventing inflammation, and avoiding autoimmune diseases. T cells are known to be critical in this regulatory process. Specifically, Th3 cells primarily secrete TGF-β along with varying levels of IL-4 and IL-10. Natural regulatory T cells and Tr1 ...
Manufactured by:Creative Biolabs based inShirley, NEW YORK (USA)
Primary antibodies are immunoglobulins that bind to a specific antigen of interest, such as protein, peptide, small molecule. And, they are commonly unconjugated. A primary antibody can recognize and bind with high affinity and specificity to purify, detect, and measure the antigen. Using a variety of hosts, such as mouse, ...
Manufactured by:Creative Biolabs based inShirley, NEW YORK (USA)
Primary antibodies are immunoglobulins that bind to a specific antigen of interest, such as protein, peptide, small molecule. And, they are commonly unconjugated. A primary antibody can recognize and bind with high affinity and specificity to purify, detect, and measure the antigen. Using a variety of hosts, such as mouse, ...
Manufactured by:Cloud-Clone Corp. based inKaty, TEXAS (USA)
In order to observe and detect the experiments of antigen-antibody specific binding, conveniently, antibody labeling tech is ususally used. The label is a kind of substances which are highly sensitive and easy to measure, the results of the experiment will be shown through the changes of color, spectrum, etc. of the labels linked with antibody, and these ...
Manufactured by:Elpiscience based inShanghai, CHINA
Elpiscience’s proprietary discovery technologies enable efficient generation of innovative cancer ...
Manufactured by:Synbio Technologies LLC based in, NEW JERSEY (USA)
Complex structures and high production costs associated with monoclonal antibodies (mAbs) have limited their achievable clinical applications. For this reason, scientists focusing on antibody drug discovery have shifted their interests toward recombinant antibody ...
Manufactured by:Synbio Technologies LLC based in, NEW JERSEY (USA)
The immune system is a very robust “antibody factory” that consistently produces antibodies to fight infections and diseases by recognizing and targeting infected cells or pathogens (antigens). The emergence of single B cell antibody technology has enabled a new strategy for discovery of naturally occurring antibody drugs. The single B cell antibody technology produces higher ...
Manufactured by:Creative Biolabs based inShirley, NEW YORK (USA)
Creative Biolabs has extensive experience to offer the novel human or humanized antibody services for either therapeutic or laboratory applications. We have three routes in developing human antibodies. The first and most straightforward method is to screen our human antibody libraries. The second method is to immunize premade “humanized” mice and then raise hybridoma cell lines [or to ...
by:GENETWORx, LLC. based inGlen Allen, VIRGINIA (USA)
Antigen tests detect proteins specific to Coronavirus within 15 minutes. These tests are quite convenient, but not as universally accurate as the PCR tests. They are generally regarded as more accurate when administered to patients currently having symptoms of COVID-19. ...
Manufactured by:Creative Biolabs based inShirley, NEW YORK (USA)
As the main component of the immune system, T cells protect the body from infections and tumors by a diversity of bio-functions, including recognition and presentation specific antigens, directly killing target cells, secretion cytokines, assisting or inhibiting antibody production by B cells, etc. These functional T cells are distinguished by a variety of ...
Manufactured by:Synbio Technologies LLC based in, NEW JERSEY (USA)
Hybridoma technology features the effective usage of innate functions of both immune and cancer cells to generate monoclonal antibodies (mAbs). The resulting hybridoma cell lines are produced to combat specific antigens of interest. Such technology has forged remarkable new approaches toward therapeutic mAb discovery, as well as disease diagnosis and ...
Manufactured by:Synbio Technologies LLC based in, NEW JERSEY (USA)
Immune Repertoire refers to the set of all functionally diversified B cells and T cells in the circulatory system of an individual at any given time. Immune repertoire sequencing (Immuno-Seq) targets at T/B lymphocytes and utilizes the 5’ Rapid Amplification of cDNA Ends (RACE) Technology. The 5’ RACE technology amplifies complementarity-determining regions (CDRs) of B cell receptors ...
Manufactured by:Antibodies Incorporated based inDavis, CALIFORNIA (USA)
Custom antibody development is rarely "cookie cutter." Our Antibody Development Group will work with your price and technical requirements to tailor a project to your expected performance characteristics. ...
Manufactured by:LAMPIRE Biological Laboratories, Inc. based inPipersville, PENNSYLVANIA (USA)
LAMPIRE began providing quality antibody support services in 1977. From antigen design and peptide synthesis to antibody purification, buffy coats (PBMCs), spleenectomies, bone marrow extractions, QC testing and labeling, our expert staff is available to assist you with every phase of antibody development. The success of your antibody project is very important to us. ...
Manufactured by:ProImmune Ltd. based inOxford, UNITED KINGDOM
Blood Processing Services for Cell-Based Assays the most critical step for successful immune monitoring projects. Getting blood processing right can be a significant challenge. Blood collection, shipping and processing is often the first point of failure for cell based immunology assays, such as ELISpot, flow cytometric phenotyping and functional cell based assays. When these assays are planned ...
Manufactured by:Immatics N.V. based inTuebingen, GERMANY
Immatics is developing Adoptive Cell Therapies, which are designed to leverage the power of T cells to actively infiltrate tumor tissue and kill tumor cells in a specific and serial ...