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Physiological Condition Services
15 services found
Manufactured by:Creative Biolabs based inShirley, NEW YORK (USA)
To retain antibody bioactivity, mild, near-physiological conditions are often used for conjugation reactions. Under these conditions, endogenous amino acids such as Lys and Cys are chemically reactive and can be used as conjugation ...
Manufactured by:Creative Bioarray based inShirley, NEW YORK (USA)
The purpose of cell cryopreservation is to maintain the survival of cells both at extreme temperatures and after thawing back to physiological ...
by:Neuron Experts based inMarseille, FRANCE
To keep up its high level of Competitiveness, Neuron Experts constantly develops new cellular models to provide the most accurate answers to customers’ needs: Development of new neurodegenerative disease models following current discoveries of new therapeutic targets, Development of new cellular models to study interaction between neurons and skin, Development of human Induced Pluripotent ...
Manufactured by:Creative Bioarray based inShirley, NEW YORK (USA)
Kupffer cells are resident liver macrophages and play a critical role in maintaining liver function. Under physiological conditions, they are the first innate immune cells that protect the liver from bacterial infection. Under pathological conditions, they are activated by different components and can differentiate into M1-like (classical) or ...
Manufactured by:Creative Bioarray based inShirley, NEW YORK (USA)
Kupffer cells are resident liver macrophages and play a critical role in maintaining liver function. Under physiological conditions, they are the first innate immune cells that protect the liver from bacterial infection. Under pathological conditions, they are activated by different components and can differentiate into M1-like (classical) or ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
Transcriptome sequencing involves sequencing the complete mRNA within cells during specific developmental stages or physiological conditions. This technique aids in studying gene expression levels and gene structure at a comprehensive level, elucidating molecular mechanisms in specific biological processes. It is widely applied in basic research, clinical ...
Manufactured by:Profacgen based inShirley, NEW YORK (USA)
Protein-protein interactions (PPIs) are crucial for understanding signaling cascades, predicting protein biological function, associating proteins with various diseases and insights into drug mechanism of ...
Manufactured by:Creative Biolabs based inShirley, NEW YORK (USA)
Autophagy is a key catabolic process that ensures the removal of excess or damaged cellular components under physiological and pathological conditions, and provides a metabolic supply in the absence of extracellular nutrients, thereby maintaining the proper balance of cells. Optimal autophagy activity plays an important protective role in several human diseases, ...
by:Cryogenetics AS based inHamar, NORWAY
Cryopreservation is the process of freezing biological material at extreme temperatures; most common -196 °C/-321 °F in liquid nitrogen (N2). At these low temperatures, all biological activity stops, including the biochemical reactions that lead to cell death and DNA degradation. This preservation method in theory makes it possible to store living cells as well as other biological ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
Sphingolipids are fundamental structural components of cell membranes, forming lipid rafts by combining with other components. Sphingolipids are involved in regulating biological processes such as cell growth, differentiation, and apoptosis. Ceramide is the central hub of the sphingolipid pathway, including sphingomyelin, glucosylceramide, and galactosylceramide, and is mainly divided into ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
Metabolic flux analysis (MFA) is a critical technique for examining the production and consumption rates of metabolites in biological systems. In systems metabolic engineering, MFA helps understand cell physiology under specific conditions and predict metabolic capacities of cells following genetic or environmental changes. MFA is also used to elucidate cellular ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
Drug screening refers to the evaluated process of substances (samples) potentially used as drugs, assessing their biological activity, pharmacological effects, and therapeutic value through appropriate methods. This process encompasses biochemical and cellular levels of screening, divided into high-throughput screening (HTS) and virtual ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
Glycosylation modifications increase the complexity of protein molecular structure and the diversity of functions, not only affecting protein folding, structure, transportation, localization, and biological activity but also regulating various physiological processes such as cell growth, division, differentiation, recognition, and adhesion through specific recognition between sugars and proteins. ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
Ion channels are made up of special proteins produced by cells, which are aggregated and embedded in the cell membrane, forming pores occupied by water molecules. These pores are the channels for water-soluble substances, which can quickly enter and exit the ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
Monoclonal antibodies (mAbs) are powerful therapeutic tools. These glycoproteins, belonging to the immunoglobulin (Ig) family, are utilized by the immune system to identify and neutralize foreign organisms or antigens. Ig’s are classified in five groups, IgA, IgD, IgE, IgG, and IgM (as α, δ, ε, γ, and μ), based on the structure of their constant regions. Among these, IgG subtypes—predominantly ...