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Physiological Condition Articles & Analysis
23 articles found
Resting state platelets have a diameter that ranges from 2 to 5μm. When physiological conditions are stable platelets remain in circulation inside the blood for approximately 7 to 10 days. ...
For instance, fatty acids can be broken down to acetyl-CoA, which enters the cycle, providing a flexible source of energy in various physiological conditions. TCA Cycle Analysis in Research Recent advancements in metabolomics have shed light on the importance of TCA Cycle analysis in various fields of research, including cancer biology, cardiovascular health, ...
These chips can simulate various physiological conditions, enabling the evaluation of drug responses at the cellular and tissue levels. ...
These nano-sized particles contain a diverse array of molecular cargo, including proteins, lipids, RNA, and metabolites, which serve as biomarkers for a variety of physiological conditions. Exosome lipidomics and metabolomics are key fields that focus on profiling the lipids and metabolites present in exosomes. ...
Glycated collagen mainly exists in various tissues in the human body, especially those rich in collagen, such as skin, bones, joints, blood vessels, and other connective tissues.Under normal physiological conditions, glycation occurs as a natural biochemical process, but its degree is usually low. ...
They act as coupling factors for bone remodeling under physiological conditions. MMP overexpression and ECM abnormalities may lead to unbalanced bone remodeling-related pathological changes in osteolysis or bone formation. ...
Given that metabolic carbon dioxide (CO2) is transported from the blood to the lungs and then exhaled during breathing, EtCO2 levels can serve as indicators of the body's physiological condition. Monitoring EtCO2 during the use of anesthesia machines can assist medical professionals assess a patient's ventilation status and provide early warning of respiratory ...
Cytokines in Asthma Asthma, a common chronic condition, is characterized by airway constriction and persistent airway inflammation involving eosinophils, neutrophils, lymphocytes, macrophages, and mast cells. ...
Cleavable linkers' performance thus hinges on their capacity to effectively distinguish between target cell circumstances and blood circulation conditions.Chemically Cleavable LinkerThere are three main types of chemically induced cleavable linkers: acid cleavable, cleavable under reducing conditions (disulfide, etc.), and linkers that can be cleaved by exogenous stimuli.l ...
It is a powerful tool and has a wide range of applications in biomacromolecule interaction analysis, cell physiology research, and immune analysis. Principle of FRET Fluorescence resonance energy transfer is an energy transfer phenomenon between two fluorescent molecules that are very close to each other. ...
The exact role of mesothelin under normal physiological conditions is unknown. MSLN knockout mice have normal development and reproductive capacity, suggesting that mesothelin function is not essential for life. ...
In addition, these compounds should remain stable under physiological conditions and have functional groups available to conjugate with antibodies. ...
GPI-linked proteins are usually involved in cell signaling and adhesion, so mesothelin may play a role in these biological processes, which, in normal physiological conditions, is still unclear. MSLN knockout mice have normal developmental and reproductive abilities, suggesting that mesothelin function is not essential for life. ...
The SIAP study investigates the effect of using Ergotrics' Inflatable Prone Support (IPS) on intra-abdominal pressure (IAP) during spine surgery. Study background The objective of this study is to demonstrate the ability of the inflatable Prone Supports (IPS) to lower the IAP of patients in the prone position. Whenever the patients’ position is changed to prone, the IAP is increased due to ...
Glutathione has two forms, reduced (G-SH) and oxidized (G-S-S-G), and reduced glutathione accounts for the vast majority under physiological conditions. Glutathione reductase catalyzes the interconversion between the two types. ...
Abstract The goal of this study is to develop unique native endothelium mimicking nanomatrices and evaluate their effects on adhesion and spreading of human umbilical vein endothelial cells (HUVECs) and aortic smooth muscle cells (AoSMCs). These nanomatrices were developed by self-assembly of peptide amphiphiles (PAs) through a solvent evaporation technique. Three PAs, one containing the ...
BTN3A1 is expressed on the cell surface and is widely expressed, consisting of two immunoglobulin-like extracellular structural domains and an intracellular B30.2 structural domain. In general, under physiological conditions, the concentration of PAG is not sufficient to stimulate γδ T cells. ...
In addition to the advantages of conventional non-target exploratory analysis, metabolomics can also detect specific metabolites related to intestinal bacteria, clearly reflecting the functional change of intestinal flora under specific conditions. Combined with the sequencing analysis technology of intestinal bacteria, a key strategy for studying the relationship between ...
In addition to these discrete physiological readouts that have been vetted for RepliGut®, Altis has a number of others under development. ...
More studies are planned to determine if this technology can predict return of bowel function or differentiate between physiologic ileus and pathologic conditions. Keywords: Electrophysiologic phenomena; Ileus; Intestinal diseases; Migrating myoelectric complex. ...