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Physiological Condition Articles & Analysis: Older

19 articles found

Glycated Collagen Protein Detection

Glycated Collagen Protein Detection

Glycated collagen mainly exists in various tissues in the human body, especially those rich in collagen, such as skin, bones, joints, blood vessels, and other connective tissues.Under normal physiological conditions, glycation occurs as a natural biochemical process, but its degree is usually low. ...

ByMtoZ Biolabs


Matrix Metalloproteinases (MMPs) - Structure, Sources and Functions

Matrix Metalloproteinases (MMPs) - Structure, Sources and Functions

They act as coupling factors for bone remodeling under physiological conditions. MMP overexpression and ECM abnormalities may lead to unbalanced bone remodeling-related pathological changes in osteolysis or bone formation. ...

ByCreative Proteomics


Cubic Gas Sensing Solutions for Anesthesia Machines

Cubic Gas Sensing Solutions for Anesthesia Machines

Given that metabolic carbon dioxide (CO2) is transported from the blood to the lungs and then exhaled during breathing, EtCO2 levels can serve as indicators of the body's physiological condition. Monitoring EtCO2 during the use of anesthesia machines can assist medical professionals assess a patient's ventilation status and provide early warning of respiratory ...

ByCubic Sensor and Instrument Co., Ltd


Cytokine Involvement in Inflammatory Immune Disorders

Cytokine Involvement in Inflammatory Immune Disorders

Cytokines in Asthma Asthma, a common chronic condition, is characterized by airway constriction and persistent airway inflammation involving eosinophils, neutrophils, lymphocytes, macrophages, and mast cells. ...

ByCreative Proteomics


ADC Cleavable Linker : Classification and Mechanism of Action

ADC Cleavable Linker : Classification and Mechanism of Action

Cleavable linkers' performance thus hinges on their capacity to effectively distinguish between target cell circumstances and blood circulation conditions.Chemically Cleavable LinkerThere are three main types of chemically induced cleavable linkers: acid cleavable, cleavable under reducing conditions (disulfide, etc.), and linkers that can be cleaved by exogenous stimuli.l ...

ByBOC Sciences


How Much Do You Know about Fluorescence Resonance Energy Transfer?

How Much Do You Know about Fluorescence Resonance Energy Transfer?

It is a powerful tool and has a wide range of applications in biomacromolecule interaction analysis, cell physiology research, and immune analysis. Principle of FRET Fluorescence resonance energy transfer is an energy transfer phenomenon between two fluorescent molecules that are very close to each other. ...

ByCreative Biostructure


Cancer Target: Mesothelin

Cancer Target: Mesothelin

The exact role of mesothelin under normal physiological conditions is unknown. MSLN knockout mice have normal development and reproductive capacity, suggesting that mesothelin function is not essential for life. ...

ByCreative Diagnostics


Antibody Drug Conjugates: "Biological Missiles" For Targeting Cancer Therapy

Antibody Drug Conjugates: "Biological Missiles" For Targeting Cancer Therapy

In addition, these compounds should remain stable under physiological conditions and have functional groups available to conjugate with antibodies. ...

ByBiopharma PEG Scientific Inc


Mesothelin: A New Target for Cancer Therapy

Mesothelin: A New Target for Cancer Therapy

GPI-linked proteins are usually involved in cell signaling and adhesion, so mesothelin may play a role in these biological processes, which, in normal physiological conditions, is still unclear. MSLN knockout mice have normal developmental and reproductive abilities, suggesting that mesothelin function is not essential for life. ...

ByBOC Sciences


Spine-Intra-Abdominal Pressure (SIAP) - Case Study

Spine-Intra-Abdominal Pressure (SIAP) - Case Study

The SIAP study investigates the effect of using Ergotrics' Inflatable Prone Support (IPS) on intra-abdominal pressure (IAP) during spine surgery. Study background The objective of this study is to demonstrate the ability of the inflatable Prone Supports (IPS) to lower the IAP of patients in the prone position. Whenever the patients’ position is changed to prone, the IAP is increased due to ...

ByErgotrics NV


The Pivotal Glutathione Reductase

The Pivotal Glutathione Reductase

Glutathione has two forms, reduced (G-SH) and oxidized (G-S-S-G), and reduced glutathione accounts for the vast majority under physiological conditions. Glutathione reductase catalyzes the interconversion between the two types. ...

ByCreative Enzymes


Effect of endothelium mimicking self-assembled nanomatrices on cell adhesion and spreading of human endothelial cells and smooth muscle cells

Effect of endothelium mimicking self-assembled nanomatrices on cell adhesion and spreading of human endothelial cells and smooth muscle cells

Abstract The goal of this study is to develop unique native endothelium mimicking nanomatrices and evaluate their effects on adhesion and spreading of human umbilical vein endothelial cells (HUVECs) and aortic smooth muscle cells (AoSMCs). These nanomatrices were developed by self-assembly of peptide amphiphiles (PAs) through a solvent evaporation technique. Three PAs, one containing the ...

ByEndomimetics


Gamma delta T cells in tumor immunotherapy   

Gamma delta T cells in tumor immunotherapy  

BTN3A1 is expressed on the cell surface and is widely expressed, consisting of two immunoglobulin-like extracellular structural domains and an intracellular B30.2 structural domain. In general, under physiological conditions, the concentration of PAG is not sufficient to stimulate γδ T cells. ...

ByCreative Biolabs


Metabolomics in Gut Microbiota Research

Metabolomics in Gut Microbiota Research

In addition to the advantages of conventional non-target exploratory analysis, metabolomics can also detect specific metabolites related to intestinal bacteria, clearly reflecting the functional change of intestinal flora under specific conditions. Combined with the sequencing analysis technology of intestinal bacteria, a key strategy for studying the relationship between ...

ByCreative Proteomics


Evaluating Microbiome Therapies with Intestinal Cell Models

Evaluating Microbiome Therapies with Intestinal Cell Models

In addition to these discrete physiological readouts that have been vetted for RepliGut®, Altis has a number of others under development. ...

ByAltis Biosystems


Cutaneous Patches to Monitor Myoelectric Activity of the Gastrointestinal Tract in Postoperative Pediatric Patients

Cutaneous Patches to Monitor Myoelectric Activity of the Gastrointestinal Tract in Postoperative Pediatric Patients

More studies are planned to determine if this technology can predict return of bowel function or differentiate between physiologic ileus and pathologic conditions. Keywords: Electrophysiologic phenomena; Ileus; Intestinal diseases; Migrating myoelectric complex. ...

ByG-Tech Medical


Hydration status and physiological workload of UAE construction workers: A prospective longitudinal observational study

Hydration status and physiological workload of UAE construction workers: A prospective longitudinal observational study

The results obtained indicated that the workers were not physiologically challenged despite fluctuating harsh environmental conditions. ...

ByScarlet Tech Ltd.


Physiological role for phosphatidic acid in the translocation of the novel protein kinase c apl ii in aplysia neurons

Physiological role for phosphatidic acid in the translocation of the novel protein kinase c apl ii in aplysia neurons

In Aplysia neurons, the inhibition of endogenous PA production by 1-butanol inhibited the physiological translocation of PKC Apl II by serotonin in the cell body and at the synapse but not the translocation of PKC Apl II-R273H. ...

ByAmerican Society for Microbiology (ASM)


Simulation models of organisational systems

Simulation models of organisational systems

These mental models are called cognitive models since they are the result of the individual's total psychological and physiological condition. Well-made cognitive models are a precondition for success in learning and using technical systems as well as a prerequisite for achieving good social relations. ...

ByInderscience Publishers

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