MedGenome - TCR Sequencing Service
From NGS Services
TCR profiling holds great potential not only for understanding the mechanisms of development of the normal immune response, but also in providing insights into disease mechanisms and development of new therapeutics and treatment modalities in infectious diseases, autoimmunity and in immuno-oncology. However, identification of all potential clonotypes in a diverse repertoire of TCRs requires sensitive methods of detection. Next-generation sequencing (NGS) technologies have recently enabled accurate detection of TCRs, and in combination with other assays, allow for the assessment of the TCR repertoire in patients which in turn is a proxy for patient prognosis and response. At MedGenome, we provide RNA based TCR repertoire profiling services for bulk and single cell analysis.
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Service Highlights
- Support with experimental design and selection of appropriate application dependent on analysis requirements, quantity and quality of input
- Higher sensitivity in detecting low frequency TCRs including samples with low input
- End-to-end solutions for extraction, sample QC, library preparation, sequencing and bioinformatics analysis
- Accurate representation of expressed TCRs vs non-functional TCRs with improved ability to call novel and low frequency clones
BioFX TCR Repertoire Analysis
- Streamlined pipeline for fast & scalable analysis
- Customized reporting
- Interactive reports
- Publication-ready figures
- Improve data interpretation with support from MedGenome's team of experts
Explore Analysis Reports
BioFX’s immune repertoire analysis platform was built using state-of-the-art analysis tools for T-cell and B-cell sequencing data. Analyze custom species including human, horse, rat, mouse and rhesus monkey. Accomplish multi-omic analysis by interrogating gene expression and VDJ sequencing data simultaneously.
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