Fatty Liver Disease Articles & Analysis
17 articles found
Non-alcoholic fatty liver disease (NAFLD) has emerged as a significant public health concern, associated with obesity, insulin resistance, and a spectrum of metabolic disorders. ...
Individuals with reduced bile production or impaired bile flow, such as those with gallbladder disease or liver dysfunction, may benefit from supplementation with ox bile extract powder to improve fat digestion and absorption, potentially alleviating symptoms related to malabsorption and steatorrhea. Additionally, by promoting the excretion of cholesterol, ox ...
Dysbiosis of the intestinal flora is associated with a variety of human metabolic diseases, such as obesity, diabetes mellitus, and nonalcoholic fatty liver disease. ...
Dysbiosis, an imbalance in gut microbial communities, has been linked to altered bile acid metabolism and, consequently, to diseases like non-alcoholic fatty liver disease (NAFLD) and type 2 diabetes. ...
However, compared with the classic uric acid-lowering drugs, its effect is relatively weak, so it is more promising to be used in patients with asymptomatic hyperuricemia or diabetes complicated with hyperuricemia. 6. Liver protection SGLT2 inhibitors can protect the liver by altering the glucose-fatty acid cycle, increasing the utilization and ...
Introduction Metabolic syndrome (MetS) is a group of clinical conditions manifested as abdominal obesity, hyperglycemia, hypertension, dyslipidemia, and chronic inflammation, concurrently leading to a marked increase in the risk of heart disease, diabetes, and stroke, or all three (1, 2). Currently, MetS is a growing health concern due to its increasing prevalence globally (3). ...
Abstract Background and aim: Nonalcoholic fatty liver disease (NAFLD) patients with significant hepatic fibrosis (stage ≥ 2) are at increased risk of liver-related morbidity and are candidates for pharmacologic therapies. In this study, we compared the diagnostic accuracy of MEFIB (the combination of magnetic resonance ...
A new study was published in March of 2021 demonstrating that elevated liver stiffness, as measured by magnetic resonance elastography (MRE), is associated with higher rates of cardiovascular disease in patients with non-alcoholic fatty liver disease (NAFLD). As clinical researchers, regulators and pharmaceutical ...
Nonalcoholic fatty liver disease (NAFLD) is associated with obesity but also found in non-obese individuals. ...
With NAFLD and NASH now affecting well over 1 billion people globally, the world needs better diagnostics to accurately detect liver disease in an affordable, easy-touse and safe manner. Abstract Non-Alcoholic Fatty Liver Disease (NAFLD) and its inflammatory stage, Non-Alcoholic SteatoHepatitis (NASH), are now a ...
The gallbladder is a slender pear- shaped organ in a right superior belly (Le Bail et al., 1992), the region below the liver which links chest to hips. Gallstones can vary between a1cm and 13cm in size. ...
Highlights The depletion of Roseburia is associated with alcohol consumption in human cohorts R. intestinalis ameliorates the experimental ALD in mice regardless of viability Flagellin from R. intestinalis protects on ethanol-disrupted gut barrier functions The ethanol-induced gut microbiota dysbiosis is restored by R. intestinalis Summary Although a link between the gut microbiota ...
Many may not have heard of nonalcoholic fatty liver (NAFL) yet it is a very common condition. If NAFL is not addressed, it can progress to a serious condition known as Nonalcoholic fatty liver disease (NAFLD) Non-alcoholic fatty liver is the buildup of extra fat in ...
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Publication Summary: The identification of targets and biomarkers and development of therapeutics for nonalcoholic fatty liver disease (NAFLD) may be accelerated by the use of well-characterized primary cell and tissue reagents, as well as improved in vitro human cell-based disease models, including three-dimensional (3D) ...
As a consequence, genetic deletion of SRSF3 in hepatocytes caused progressive liver disease and ultimately led to hepatocellular carcinoma. Here we show that SRSF3 is decreased in human liver samples with nonalcoholic fatty liver disease (NAFLD), nonalcoholic steatohepatitis (NASH), or cirrhosis ...
Publication Summary: Nonalcoholic fatty liver disease (NAFLD) is a chronic condition that originates as lipid accumulation within hepatocytes (steatosis) and progresses into nonalcoholic steatohepatitis (NASH), characterized by lipid accumulation, inflammation, oxidative stress, and fibrosis. NAFLD is now recognized as the most common cause of ...
Publication Summary: Nonalcoholic fatty liver disease (NAFLD) is a chronic condition that originates as lipid accumulation within hepatocytes (steatosis) and progresses into nonalcoholic steatohepatitis (NASH), characterized by lipid accumulation, inflammation, oxidative stress, and fibrosis. NAFLD is now recognized as the most common cause of ...