- Home
- Services
- north america
- clinical medicine
- inflammatory response
Show results for
Refine by
Clinical Medicine Services In North America
33 services found
Manufactured by:Immatics N.V. based inTuebingen, GERMANY
Immatics is developing Adoptive Cell Therapies, which are designed to leverage the power of T cells to actively infiltrate tumor tissue and kill tumor cells in a specific and serial ...
by:iFyber, LLC based inIthaca, NEW YORK (USA)
Biomarkers are measurable substances in an organism whose presence can be indicative of a disease state, infection, or environmental exposure. This detectable response can vary based on the specific medical intervention and may give clues regarding disease progression, wound healing, or the physiological side-effects of a device or drug ...
Manufactured by:Creative Biolabs based inShirley, NEW YORK (USA)
Protein drugs are protein products with certain biological activities for the prevention and diagnosis of diseases. They can be derived from plants and animals, or developed through biotechnology research. Protein drugs in a broad sense include all products whose chemical nature is protein or polypeptide, such as hormones, growth factors/cytokines, plasma proteins, enzymes, coagulation factors, ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
Peptidomics refers to the study of all endogenous bioactive peptides in organism, cell, or tissue. Bioactive peptides are biologically active substances involved in various cellular functions within the organism, which include cytokines, growth hormones, and disease-specific degradation fragments of certain proteins in body fluids. ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
Metabolic bone disease encompasses a range of bone disorders caused by congenital or acquired factors that disrupt normal bone metabolism and biochemical states, leading to disorders in bone biochemistry and metabolism. These disorders stem from abnormalities in three key areas: bone resorption, bone growth, and mineral deposition. Increasingly, research has identified numerous cytokines involved ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
Cell death occurs through several pathways including apoptosis, necrosis, and other emergent pathways. Apoptosis is pivotal in immune responses, involving processes such as intracellular balance, T cell clustering, the death of reactive lymphocytes, and cytotoxity of target cells. Apoptosis involves key components like APO-1/Fas, a receptor essential for apoptotic signaling; Caspase-3, crucial ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
To maintain the immune system's homeostasis, multiple control systems are essential for managing infections, inhibiting tumor growth, preventing inflammation, and avoiding autoimmune diseases. T cells are known to be critical in this regulatory process. Specifically, Th3 cells primarily secrete TGF-β along with varying levels of IL-4 and IL-10. Natural regulatory T cells and Tr1 cells can ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
Obesity is a systemic disease, not only does it lead to changes in body shape, but it also brings along various diseases and complications, affecting an individual's overall health. Common complications, such as hyperglycemia, hyperlipidemia, and hypertension, are medically termed as "metabolic syndrome". The fluid factors secreted by adipose tissue propel the development of metabolic syndrome ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
During the tumor formation process, cancer cells release various cytokines and growth factors into the surroundings and reprogram many other types of cells to establish a tumor microenvironment. As a result, tumor tissues almost always contain a large number of endothelial cells, fibroblasts, and infiltrating inflammatory cells, which in turn produce various cytokines. Tumor-derived VEGF acts on ...
Manufactured by:Catalent, Inc based inSomerset, NEW JERSEY (USA)
At Catalent, our methodologies work toward reducing the overall costs and time it takes to get your product to the clinic. With decades of experience in analytical development, we understand our clients’ needs, the current regulatory environment, and have a history of the development and qualification of analytical methods. We operate with a forward-looking methodology by deploying robust ...
by:Xeno Diagnostics, LLC based inIndianapolis, INDIANA (USA)
Xeno Diagnostics is a provider of in-vitro assays for early-stage drug development. We support biotech companies, pharmaceutical and academic life science organizations to enhance the quality and speed of their research. Our suite of assays and interaction with investigators have been designed to move the process forward. We are truly dedicated to making a difference for our ...
Manufactured by:Creative Biolabs based inShirley, NEW YORK (USA)
As the main component of the immune system, T cells protect the body from infections and tumors by a diversity of bio-functions, including recognition and presentation specific antigens, directly killing target cells, secretion cytokines, assisting or inhibiting antibody production by B cells, etc. These functional T cells are distinguished by a variety of surface receptors, biomarkers, and ...
Manufactured by:Pluristem Therapeutics Inc. based inHaifa, ISRAEL
COVID-19 is caused by infection with the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that may cause clusters of severe respiratory illness associated with the need for intensive care unit (ICU) admission and high mortality. Studies have shown that Acute Respiratory Distress Syndrome (ARDS) following viral pneumonia is one of the most common causes of death from ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
One of the main obstacles in drug development is how to deliver drugs effectively to target cells. In general, macromolecules such as proteins and mRNA cannot penetrate the cell membrane because the cell membrane has acquired protective mechanisms through evolution. However, viruses can deliver their genetic material into cells. Therefore, viruses and virus-like particles are widely used to ...
Manufactured by:Creative Biogene based inShirley, NEW YORK (USA)
CpG oligodeoxynucleotides (CpG ODN) is a synthetic oligodeoxynucleotide, containing unmethylated CpG motifs derived from bacterial DNA, with immunostimulatory activities. Several studies have shown that CpG ODN is able to stimulate cells that express TLR9, initiating an immunomodulatory cascade that culminates in the production of Th1 and proinflammatory cytokines and ...
by:Champions Oncology, Inc. based inHackensack, NEW JERSEY (USA)
Champions Oncology’s Analytical Testing platforms can be used to gather additional data at the endpoint of a preclinical model or ex vivo assay. Using multiplex cytokine assays with flow cytometry readouts, immune cell cytokine intracellular and extracellular staining upon activation can be assessed. Champions Oncology can also collect tissues from your in vivo studies and ...
Manufactured by:Invicro, LLC based inNeedham, MASSACHUSETTS (USA)
Our diverse team of experts have experience in instrument engineering, signal processing, and pharmaceutical R&D, collectively resulting in a long history designing and executing imaging and pathology studies. Our scientists have performed hundreds of studies across multiple therapeutic research areas, including oncology, neuroscience, inflammation, cardiovascular, metabolic, and ...
Manufactured by:CytoSorbents Corporation based inMonmouth Junction, NEW JERSEY (USA)
Experiences showed that the use of CytoSorb can help the body to fight the harmful effects of COVID-19, if one or more of the following criteria is ...
Manufactured by:Nexelis based inSeattle, WASHINGTON (USA)
Testing Services to Support Your Preclinical and Phase I-IV Drug Programs. Nexelis, a Q² Solutions Company, provides biomarker assay services in inflammation and immunology, oncology, organ injury (renal), nutritional health, cardiovascular, metabolic (NASH/NAFLD) and infectious diseases. Our scientists approach your projects with flexible and creative solutions, developing fit-for-purpose ...
by:Activation Laboratories Ltd. based inAncaster, ONTARIO (CANADA)
Our scientists are highly experienced in both implementing client assays and developing them de novo. Our Canadian laboratories undergo routine audits from both regulatory agencies and clients alike. Our In Vitro Assay Service and Cell Based Bioassays Services include ...