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Drug Interaction Equipment Supplied In North America

42 equipment items found
In North AmericaAvailable In North AmericaNear North America

Sigma-Aldrich SynVivo SynTumour - Model VIV105015STU3 - 3D Cancer Model Chip, Microvascular Network Configuration, 8 Um Pillar

Sigma-Aldrich SynVivo SynTumour - Model VIV105015STU3 - 3D Cancer Model Chip, Microvascular Network Configuration, 8 Um Pillar

Manufactured by:Sigma-Aldrich   based inBellefonte, PENNSYLVANIA (USA)
SynTumor cancer model chip- Microvascular design-Barrier type: Pillars, Distance between pillars: 50 μm, Pillar Diameter: 10 μm, Barrier height: 8 μm, Travel/barrier width: 50 μm, Device depth: 100 μm. SynTumor is a 3D tissue model for real-time visualization and quantitative assessment of cell-cell and cell-drug interactions in a physiologically ...
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Allevi - Model A-HUCPI - Human Hepatocytes Cells

Allevi - Model A-HUCPI - Human Hepatocytes Cells

Manufactured by:Allevi, Inc.   based inPhiladelphia, PENNSYLVANIA (USA)
Clinically relevant drug-drug interactions (DDI) are a serious concern for any new drug development project. To better support capturing the multiple mechanisms of DDI potential using primary hepatocytes, we now offer Interaction Qualified Human Hepatocytes (Catalog HUCPI) which are characterized for 3 major ...
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Emulate - Duodenum Intestine-Chip

Emulate - Duodenum Intestine-Chip

Manufactured by:Emulate   based inBoston, MASSACHUSETTS (USA)
Study drug absorption and drug-drug interactions in a primary organoid-based model of the human small ...
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Emulate - Kidney-Chip

Emulate - Kidney-Chip

Manufactured by:Emulate   based inBoston, MASSACHUSETTS (USA)
Evaluate drug candidate toxicity at clinically relevant concentrations in a co-culture human kidney model. Predicting drug-induced kidney toxicity and drug-drug interactions continues to be a challenge due to a reliance on immortalized cell line culture or animal models that do not translate to human response. ...
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SynTumor - 3D Cancer Model

SynTumor - 3D Cancer Model

Manufactured by:SynVivo, Inc.   based inHuntsville, ALABAMA (USA)
SynTumor is a 3D tissue model for real-time visualization and quantitative assessment of cell-cell and cell-drug interactions in a physiologically and morphologically realistic tumor microenvironment. The system enables (a) circulation in the microvasculature, (b) transport across the vessel walls, and (c) delivery to the tumors. Starting with scans of vascular ...
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Virpax - Model NobrXiol - Intranasal Pharmaceutical-Grade Cannabidiol (CBD)

Virpax - Model NobrXiol - Intranasal Pharmaceutical-Grade Cannabidiol (CBD)

Manufactured by:Virpax Pharmaceuticals   based inBerwyn, PENNSYLVANIA (USA)
Since peripheral exposure via the plasma will be reduced by the nose to brain delivery, we believe there will be negligible liver first-pass metabolism. NobrXiol may not be metabolized in the liver avoiding drug to drug interactions caused by oral pharmaceutical-grade CBD. By avoiding the first pass effect Intranasal NobrXiol may eliminate ...
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Agonist

Agonist

by:DEARGEN Inc.   based inDaejeon, SOUTH KOREA
Agonist refers to substances that activate a specific target protein. It can easily be viewed as the opposite of inhibitor. Until now, Deargen's drug-target interaction (DTI) was predicted based on the binding affinity between the substance and the target protein, which causes barrier to distinguish between the inhibition and activation activity. In addition, the ...
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InSilicoCARDIO - Model STrhiPS - Silico Tool for Early Screening

InSilicoCARDIO - Model STrhiPS - Silico Tool for Early Screening

Manufactured by:InSilicoTrials Technologies    based inStafford, VIRGINIA (USA)
A new in silico tool for early screening of compounds multicurrent blocking effects on a population of hiPSC-derived ...
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RapidAIM - Microbiome Platform to Assess Drug-Microbiome Interactions

RapidAIM - Microbiome Platform to Assess Drug-Microbiome Interactions

Manufactured by:MedBiome Inc.   based inOttawa, ONTARIO (CANADA)
The RapidAIM technology allows the rapid screening of compounds against individual human microbiomes and greatly accelerates the discovery of compounds that target the human microbiomes. Our current technology can also be used to de-risk compounds, stratify patients based on their microbiome responses and other ...
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InSilicoCARDIO - Model CiPA In Silico - Solution for Pharma

InSilicoCARDIO - Model CiPA In Silico - Solution for Pharma

Manufactured by:InSilicoTrials Technologies    based inStafford, VIRGINIA (USA)
A new model that combines dynamic drug-hERG interactions and multichannel pharmacology to improve prediction of drugs’ torsadogenic ...
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S1 Biopharma - Model Lorexys - Targets Hypoactive Sexual Desire Disorder (HSDD)

S1 Biopharma - Model Lorexys - Targets Hypoactive Sexual Desire Disorder (HSDD)

Manufactured by:S1 Biopharma, Inc.   based inNew York City, NEW YORK (USA)
S1 Biopharma’s first-in-class lead product, Lorexys, targets hypoactive sexual desire disorder (HSDD) in women, the most common type of female sexual dysfunction. Lorexys is designed to restore the balance of three neurotransmitters – dopamine, serotonin and norepinephrine – that are known to regulate sexual inhibition and sexual excitation. An oral, non-hormonal, fixed-dose ...
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DEARGEN - Model DearDTI - Drug Technology

DEARGEN - Model DearDTI - Drug Technology

by:DEARGEN Inc.   based inDaejeon, SOUTH KOREA
DearDTI presents drug candidates with a good efficacy by predicting the binding affinity, based on information about the compound-protein ...
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Codonics - Safe Label System (SLS)

Codonics - Safe Label System (SLS)

Manufactured by:Codonics   based inMiddleburg Heights, OHIO (USA)
Safe, compliant, fast medication labeling — anywhere medications are prepared. Codonics Safe Label System (SLS) is an award-winning, FDA-approved medical device that improves the safety and accuracy of medication management, integrating worldwide recognized best practices and international standards. A complete solution to enhance patient care, SLS uses barcode technology to read ...
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Jubilant HICON - Kit for the Preparation of Sodium Iodide I 131 Capsules and Solution USP Therapeutic – Oral

Jubilant HICON - Kit for the Preparation of Sodium Iodide I 131 Capsules and Solution USP Therapeutic – Oral

Manufactured by:Jubilant DraxImage Inc. dba Jubilant Radiopharma   based inKirkland, Montréal, QUEBEC (CANADA)
The concentrated solution (1 Ci per mL) is intended for use in the preparation of capsules and solution of varying strengths for oral administration for ...
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Aldactone - Film Coated Spironolactone Tablet

Aldactone - Film Coated Spironolactone Tablet

Manufactured by:Pfizer Inc.    based in, NEW YORK (USA)
These highlights do not include all the information needed to use ALDACTONE safely and effectively. See full prescribing information for ...
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Orenitram - Extended-Release Tablets

Orenitram - Extended-Release Tablets

Manufactured by:United Therapeutics Corporation   based inSilver Spring, MARYLAND (USA)
Orenitram is a prostacyclin mimetic indicated for treatment of pulmonary arterial hypertension (PAH; WHO Group 1), to delay disease progression and to improve exercise capacity. The studies that established effectiveness included predominately patients with WHO functional class II-III symptoms and etiologies of idiopathic or heritable PAH (66%) or PAH associated with connective tissue disease ...
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Virpax - Model Envelta - Endogenous Enkephalin Intranasal Spray

Virpax - Model Envelta - Endogenous Enkephalin Intranasal Spray

Manufactured by:Virpax Pharmaceuticals   based inBerwyn, PENNSYLVANIA (USA)
Endogenous peptides with analgesic potential include endorphins via binding to the mu receptor, dynorphins via the kappa receptor and enkephalins via the delta receptor. Kappa and delta opioid agonists have been shown to provide analgesic benefit while sparing mu agonist toxicity1. Preclinical data supports analgesia from enkephalin without significant opioid tolerance or drug liking. Typically, ...
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Ecoorganic - Concentrated Disinfectan

Ecoorganic - Concentrated Disinfectan

Manufactured by:Ecoorganic   based inKyiv, UKRAINE
Concentrated disinfectant for hygienic and antiseptic hand treatment. Made according to the recipe recommended by WHO. Can be used to disinfect the hands of health care workers, elbow bends of donors, skin treatment of the operating room, injection field, skin treatment with invasive methods of diagnosis and treatment of patients and skin decontamination of food processing staff, catering and ...
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Aphios - Model Zindol - Chemotherapy

Aphios - Model Zindol - Chemotherapy

by:Aphios Corporation   based inWoburn, MASSACHUSETTS (USA)
Despite the widespread use of the 5-HT3 receptor antagonist anti-emetics such as Palonosetron (Aloxi; Eisai), Ondansetron (Zofran®; GSK), Granisetron (Kytril®; Roche Pharmaceuticals), and Dolasetron (Anzemet®; Aventis), CINV continues to be reported by up to 70% of adult patients receiving highly emetogenic chemotherapy agents and 58% of school-age and adolescent-age children ...
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MedChemExpress - Model N-Acetylcarnosine - 56353-15-2

MedChemExpress - Model N-Acetylcarnosine - 56353-15-2

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
N-Acetylcarnosine, a natural histidine-containing dipeptide, is a source of pharmacological principal L-carnosine. N-Acetylcarnosine is a potent ophthalmic agent in human ...
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