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Preclinical Data From Cytotil15 Program Equipment Supplied In Usa Pennsylvania
14 equipment items found
Manufactured by:BriaCell Therapeutics Corp. based inWest Vancouver, BRITISH COLUMBIA (CANADA)
Early-Stage Preclinical Program: 30% of all human malignancies display activating RAS mutations with another 60% showing over-activity of Ras-signaling pathways. BriaCell’s novel, proprietary PKCδ inhibitors have shown activity against multiple RAS transformed tumors. This target has an attractive safety profile based on in vivo studies and knock out mouse studies. PKCδ also has ...
Manufactured by:Biopeptek Pharmaceuticals LLC based inMalvern, PENNSYLVANIA (USA)
Biopeptek is a leading manufacturer of synthetic peptide Active Pharmaceutical Ingredient (API). We offer custom APIs for pharmaceutical research & development organizations world-wide to support pre-clinical and clinical studies. We also support our clients for preparation of Chemistry, Manufacturing and Controls (CMC) regulatory ...
by:Micro Photonics Inc. based inAllentown, PENNSYLVANIA (USA)
The InAlyzer DEXA scan can analyze bone mineral density (BMD) and body composition (BMC, FAT, LEAN) of live lab animals in units of 0.001gm with simple anesthesia and without dissection. Serial assessment is possible for each live lab animal, saving animals and cost. Radiation exposure of researchers is blocked with internal protection, making the InAlyzer safe, effective, and ...
Manufactured by:Context Therapeutics Inc. based inPhiladelphia, PENNSYLVANIA (USA)
There is growing interest in applying antibody modalities including bispecifics, antibody-drug conjugates, and CART to solid tumors. However, identifying appropriate tumor-specific targets that avoid adverse effects in healthy tissue has been challenging. The tight junction protein Claudin 6 (CLDN6) is a validated therapeutic target for many solid tumor types, including ovarian, endometrial, ...
Manufactured by:Cabaletta Bio, Inc. based inPhiladelphia, PENNSYLVANIA (USA)
PLA2R-CAART is being developed to treat patients with PLA2R-associated membranous nephropathy (MN), a B cell-mediated autoimmune disease that affects the kidneys. B cells produce autoantibodies, which are believed to form immune complexes that are deposited at the glomerular basement membrane, causing damage of the filtration barrier, and leading to proteinuria. Over time, ...
Manufactured by:Centinel Spine based inWest Chester, PENNSYLVANIA (USA)
Sixth generation STALIF® technology, STALIF M-Ti™ incorporates a novel, circumferential, titanium surface, PEEK Integrated Interbody™ design that is raising the Gold Standard of lumbar interbody ...
Manufactured by:Galera Therapeutics, Inc. based inMalvern, PENNSYLVANIA (USA)
Avasopasem manganese (GC4419) is an investigational selective dismutase mimetic drug in development as a radioprotector in combination with radiation therapy (RT), with the goal to reduce side effects from radiation therapy. In preclinical studies, our selective dismutase mimetics significantly reduced immediate and long-term radiation damage to normal tissue in a variety of organs. Avasopasem ...
Manufactured by:Centinel Spine based inWest Chester, PENNSYLVANIA (USA)
Based on the successful STALIF C® device, STALIF C-Ti™ incorporates a novel, titanium-surfaced PEEK Integrated Interbody™ design that is raising the Gold Standard of cervical interbody. The Ti-ACTIVE™ surface provides a three-dimensional texturized surface that is microporous with hydrophilic properties, to facilitate human mesenchymal stem cell (hMSC) attachment and ...
Manufactured by:Pacific Edge Ltd based inDunedin,, NEW ZEALAND
Cxcolorectal is a prognostic gene signature for patients diagnosed with stage II or stage III colorectal cancer. The test predicts the aggressiveness of the tumour, allowing physicians to make the best decision regarding treatment for the ...
Manufactured by:Virpax Pharmaceuticals based inBerwyn, PENNSYLVANIA (USA)
Endogenous peptides with analgesic potential include endorphins via binding to the mu receptor, dynorphins via the kappa receptor and enkephalins via the delta receptor. Kappa and delta opioid agonists have been shown to provide analgesic benefit while sparing mu agonist toxicity1. Preclinical data supports analgesia from enkephalin without significant opioid tolerance or drug liking. Typically, ...
Manufactured by:TELA Bio, Inc. based inMalvern, PENNSYLVANIA (USA)
OviTex, a Reinforced Tissue Matrix, was designed in collaboration with surgeons and healthcare providers to address the unmet clinical and financial needs in hernia repair and abdominal wall reconstruction. Our solutions are comprised of polymer fiber interwoven through layers of biologic material in a “lockstitch” pattern, which creates a unique embroidered construction, offering a ...
Manufactured by:Ocugen, Inc. based inMalvern, PENNSYLVANIA (USA)
OCU200 is a biologic product candidate in preclinical development for treating severely sight-threatening diseases like Diabetic Macular Edema (DME), Diabetic Retinopathy (DR), and Wet Age-Related Macular Degeneration (Wet-AMD). Patients affected by these diseases share common symptoms, such as blurriness in vision and progressive vision loss as the disease progresses. The formation of fragile ...
Manufactured by:Adaptimmune LLC based inPhiladelphia, PENNSYLVANIA (USA)
Our goal is to revolutionize cancer therapy on a global basis by developing TCR T-cell therapies (called SPEAR T-cells) with the potential to treat a wide range of cancer types and patients. Our TCR T-cell therapies have advantages over other immune therapies and cancer therapies. The video below provides more ...
Manufactured by:Neuropathix, Inc. based inDoylestown, PENNSYLVANIA (USA)
Neuropathix has focused its science on the research and development of a pipeline of next generation socially responsible pain management ...