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Preclinical Phase Equipment Supplied In North America
22 equipment items found
by:AbelZeta Inc. based inRockville, MARYLAND (USA)
PRODUCT: C-CAR036. INDICATION: Solid Tumor. PLATFORM: CAR-T. PRECLINICAL: Claudin 18.2. IIT: -. PHASE 1/1B: -. PHASE 2: -. PARTNERS: ...
by:AbelZeta Inc. based inRockville, MARYLAND (USA)
PRODUCT: C-CAR031. INDICATION: HCC. PLATFORM: CAR-T. PRECLINICAL: GPC3. IIT: -. PHASE 1/1B: -. PHASE 2: -. PARTNERS: ...
by:AbelZeta Inc. based inRockville, MARYLAND (USA)
PRODUCT: C-CAR168. INDICATION: Autoimmune. PLATFORM: CAR-T. PRECLINICAL: CD20 / BCMA. IIT: -. PHASE 1/1B: -. PHASE 2: -. PARTNERS: ...
by:AbelZeta Inc. based inRockville, MARYLAND (USA)
PRODUCT: C-CAR066. INDICATION: r/r B-NHL. PLATFORM: CAR-T. PRECLINICAL: CD20. IIT²: - PHASE 1/1B: - PHASE 2: - PARTNERS: Johnson & ...
Manufactured by:EndoLogic LLC based inClifton, NEW JERSEY (USA)
Renzapride is best suited as a treatment of Diabetic Gastroparesis, a condition with a significant unmet treatment options. In the numerous trials that have been done using Renzapride more than 5000 patients have been treated with Renzapride. An extensive cardiac safety evaluation under the FDA mandated Thorough QT trial has shown that Renzapride does not have any cardiac safety ...
by:Micro Photonics Inc. based inAllentown, PENNSYLVANIA (USA)
Radiation exposure of researchers is blocked with internal protection, making the InAlyzer safe, effective, and accurate for use in the preclinical research phase. Optional model: For mid-sized laboratory animals such as rabbits and guinea pigs, Save time, cost, and animals, Automated, accurate, and precise measurement, High resolution images ...
Manufactured by:CanaQuest Medical Corp. based inMississauga, ONTARIO (CANADA)
A variety of things are evaluated through clinical trials, including: Effectiveness of medications, minimum and ultimate dose, medication combinations. Based on positive results from the preclinical research, we are ready to move forward with a clinical trial to see how well it works in humans. Clinical trials happen in several phases during which different ...
Manufactured by:Cabaletta Bio, Inc. based inPhiladelphia, PENNSYLVANIA (USA)
PLA2R-CAART is being developed to treat patients with PLA2R-associated membranous nephropathy (MN), a B cell-mediated autoimmune disease that affects the kidneys. B cells produce autoantibodies, which are believed to form immune complexes that are deposited at the glomerular basement membrane, causing damage of the filtration barrier, and leading to proteinuria. Over time, ...
Manufactured by:SiO2 Materials Science based inAuburn, ALASKA (USA)
We provide a common drug contact surface starting at the research and pre-clinical drug development phases, through clinical trials, and on through to commercial ...
by:Alume Biosciences, Inc. based inCA, CALIFORNIA (USA)
Loss of nerve function can be catastrophic. As many as 80% of prostate surgeries result in incontinence or erectile dysfunction because of nerve damage, and as many as 25% of head and neck surgeries damage the facial nerves. The mission of Alume Biosciences is to make our proprietary nerve illumination technology available for surgeons so that patients everywhere can benefit. Learn how you can ...
Manufactured by:TVAX Biomedical, Inc. based inOlathe, KANSAS (USA)
TVAX®’s second candidate (TVI-Kidney-1) is being evaluated for the treatment of kidney cancer and targets stage 4 renal cell ...
Manufactured by:TVAX Biomedical, Inc. based inOlathe, KANSAS (USA)
The drug candidate has received Fast Track Designation by the US Food and Drug Administration (FDA) to test TVI-Brain-1 in a Phase 2b clinical study for glioblastoma multiforme (GBM). The Fast Track Designation is supported by positive Phase 2 clinical data, as well as extensive preclinical and Phase 1 safety ...
Manufactured by:SiO2 Materials Science based inAuburn, ALASKA (USA)
We provide a common drug contact surface starting at the research and pre-clinical drug development phases, through clinical trials, and on through to commercial ...
Manufactured by:Ocean Biomedical based inProvidence, RHODE ISLAND (USA)
New therapeutic antibodies for effective treatment of NSCLC and other disorders. We are moving towards Phase 1 clinical trials of patented antibodies for the treatment of NSCLC. Our lead program, OCX-253 was chosen because it stimulates the B-Raf protooncogene while inhibiting apoptosis, NK cell accumulation and activation, LIM kinase 2, p-cofilin, the tumor suppressor PTEN, and p53. In addition, ...
Manufactured by:KaVo Dental GmbH based inBiberach/Riß, GERMANY
Being designed on the basis of the KaVo ESTETICA E50 Life, it meets the state-of-the-art standards - especially in terms of ergonomics, operability, hygiene and reliability. The modular concept of the DSE Clinical E50 Life provides a high degree of flexibility. The unit allows for optimal adaptation to the individual requirements, demands and spatial conditions of each clinic. ...
Manufactured by:Invicro, LLC based inNeedham, MASSACHUSETTS (USA)
Invicro has spent 20 years specializing in neuroscience imaging solutions for preclinical, early phase and late phase clinical studies. Our capabilities span from in vitro assays to in vivo imaging using PET, SPECT and MRI imaging biomarkers in CNS drug development and CNS clinical trials. We have expertise in coordinating worldwide ...
by:Aphios Corporation based inWoburn, MASSACHUSETTS (USA)
An alpha (α)-secretase modulator for ameliorating Alzheimer’s Disease pathophysiology and cognitive impairment with neuroprotection. Aphios is developing APH-1104, a more potent analog of Bryostatin-1, which is neuroprotective by α-secretase activation via novel PKC isoforms, down-regulation of pro-inflammatory and angiogenic processes and the substitution of β-amyloid for ...
Manufactured by:CanaQuest Medical Corp. based inMississauga, ONTARIO (CANADA)
Clinical testing on humans can only begin after a pre-clinical phase, involving laboratory studies (in vitro) and tests on animals, which has shown that the experimental drug is considered safe and effective. However, no animal is sufficiently similar to humans (even genetically modified ones) to make human testing unnecessary. For this reason, the experimental drug must also be tested on humans. ...
Manufactured by:ACROBiosystems based inNewark, DELAWARE (USA)
IL-15,Interleukin-15,IL15,Interleukin ...
Manufactured by:Microbion Corporation based inBozeman, MONTANA (USA)
Cystic Fibrosis (CF) lung disease, which is estimated to affect more than 30,000 in the US and 70,000 worldwide1, is characterized by chronic bacterial infection and severe inflammation that leads to progressive deterioration in lung function. Chronic pulmonary infections in CF patients, a significant portion which involves Pseudomonas aeruginosa, are characterized by persistence, biofilm ...