Epidemiology Articles
-
Rare Disease Research: from Diagnostic Development to Small Molecule Drug Development
Rare diseases, also known as orphan diseases, affect a small percentage of the population, making them particularly challenging to diagnose and treat. However, thanks to advancements in medical research and technology, significant progress has been made in the field of rare disease research, from developing accurate diagnostic tools to making effective small-molecule drugs. One of the biggest ...
By Protheragen
-
Unlocking the Secrets of Protein and Antibody Development
In the vast and intricate world of biology, the development of proteins and antibodies stands as a crucial field of study, driving advancements in medicine, biotechnology, and beyond. From the fundamental building blocks of life to the complex molecules that defend our bodies, these remarkable biomolecules hold the key to unlocking new frontiers in scientific understanding and practical ...
-
Enzyme Molecular Dynamics Simulation Service: Unveiling the Intricate Dance of Life's Catalysts
As professional biologists, we are enthralled by the intricate dance of life's catalysts - enzymes. These remarkable protein molecules are the unsung heroes of the biological world, orchestrating the myriad chemical reactions that sustain and power the living organisms around us. To truly understand the structural and functional intricacies of these vital biomolecules, we turn to the powerful ...
-
Drug Discovery: Unraveling the Mysteries of Therapeutic Agents
In the vast and ever-evolving field of medicine, the discovery of new drugs has been a critical pursuit, offering hope and relief to countless individuals suffering from various ailments. The process of drug discovery is a complex and multifaceted endeavor, involving the integration of diverse scientific disciplines, including biology, chemistry, and computational science. At the heart of this ...
-
Karyotype Analysis for Rare Disease
Karyotype analysis refers to the pairing and grouping of chromosomes to reveal whether the organism accords with the inherent chromosomal characteristics, to determine if the organism has chromosomal abnormalities. Karyotype analysis can detect whether there are abnormalities in chromatin length, centromere position, the ratio of long and short arms, and the presence or absence of satellites. ...
By Protheragen
-
Food Nutrition Enhancers
Food nutrition enhancer, also called food nutritional fortifier, refers to natural or synthetic nutrients added to food in order to increase its nutritional content. It can not only supplements people's daily nutritional intake, but also has a positive effect on disease prevention and control. The food nutrition enhancers can be divided into four main categories as following. Vitamins Vitamins ...
-
A Closer Look at Reporter Lentiviral Particles: Tool for Biomedical Research
Introduction For years, scientists have leveraged the brilliant potentialities of genetic science to explore how cells function and interact in living organisms. Among the numerous tools employed are "reporter systems," which use a visible marker to track gene expression, protein interactions, and other vital biological processes. One such system employs reporter lentiviral particles, using the ...
-
Unleashing the Potential of Bacterial Genome Editing: A Gateway to the Future
Technological advancements and innovative research have continuously led to the discovery and development of new methodologies in the field of biological and medical sciences. One such breakthrough discovery is bacterial genome editing, which opens a new world of opportunities and challenges in the field of biotechnology and genomics. Understanding Bacterial Genome Editing Bacterial genome ...
-
Unveiling the Potential of Premade RNA-LNP Products
Introduction RNA Lipid Nanoparticles (LNP) technology has rapidly gained prominence in the health and scientific domain, primarily due to its significant role in carrying the mRNA of the COVID-19 vaccines developed by Pfizer/BioNTech and Moderna. Yet, the potential of this technology spans beyond the confines of these vaccines or even the health industry. As research into premade RNA-LNP products ...
-
Unraveling the Complexity of Glycans: Exploring Glycan Arrays and Their Applications
Introduction Glycans, also known as carbohydrates, are complex molecules that play a crucial role in various biological processes. They are involved in cell signaling, immune responses, and cell adhesion, among other functions. Glycan arrays have emerged as powerful tools for studying the interactions between glycans and other molecules. In this blog post, we will delve into the world of glycan ...
By CD BioGlyco.
-
Unveiling the Intricacies of DNM1L: Function, Associated Diseases, and Inheritance Patterns
Introduction The human body is a complex network of genes and proteins, each playing a crucial role in maintaining our health. One such gene, DNM1L, has garnered significant attention in recent years due to its vital functions and its association with various diseases. In this blog post, we will delve into the world of DNM1L, exploring its function, the diseases it is linked to, and the ...
-
Innovative Diagnostic Development Urges Rare Disease Therapies
Rare diseases are characterized by their low prevalence, affecting a small number of people across the world. These diseases often come with significant challenges, including accurate diagnosis, availability of effective treatments, and limited resources for research and development. However, recent advancements in diagnostics technology hold promise for speeding up the field of rare disease ...
By Protheragen
-
Lipids Used in COVID-19 mRNA Vaccines
The COVID-19 pandemic has killed millions of people. Vaccines certainly are the most outstanding ways to prevent major diseases and death, though they haven't eliminated infections. At present, the most effective vaccine is the mRNA vaccine developed by Pfizer-BioNTech and Moderna. Before that, mRNA technology stopped in the lab phase. How to apply mRNA technology to more complex diseases in the ...
By BOC Sciences
-
New Technology to Promote Drug Development-AI Technology
For a long time, the research and development of each new drug has faced the challenges of high cost and long cycle. In response to these challenges, major pharmaceutical companies have shifted from targeting common diseases to developing drugs for specific diseases. At the same time, these companies are constantly looking for new technologies for new drug development, such as high-throughput ...
By BOC Sciences
-
Nanobodies Definition, Structure, Advantages and Applications
What is a Nanobody?Nanobodies are the smallest functional single-domain antibodies known to be able to stably bind to antigens, and have unique structural and functional advantages. The molecular weight of nanobodies is only 12-15 kDa, which retains the antigen binding ability of traditional antibodies. However, nanobodies have higher solubility and stability, and have unique advantages in ...
By BOC Sciences
-
The Liposome-Based PROTAC Strategy
Proteolysis Targeting Chimeras (PROTACs) are a novel approach for degrading target proteins. Recently, a new split-and-mix PROTAC (SM-PROTAC) system based on liposome self-assembly, known as LipoSM-PROTAC, was reported in the Journal of the American Chemical Society. The LipoSM-PROTAC system exhibits selective degradation of target proteins, with folate serving as a key ligand. In this study, the ...
By BOC Sciences
-
An Overview of Isotopes
What are Isotopes? Isotopes are different atoms of the same element with the same number of protons and different numbers of neutrons called isotopes of each other, which can also be interpreted as different nuclides of the same element called isotopes of each other. An isotope is one of two or more atoms of the same chemical element with the same atomic number, occupying the same position on the ...
By BOC Sciences
-
Drug-Loaded Liposomes: Tiny Spheres with Big Potential
Imagine tiny bubbles, smaller than a red blood cell, carrying powerful medicines directly to diseased cells. This isn't science fiction, it's the cutting edge of drug delivery with drug-loaded liposomes. What are liposomes? Liposomes are microscopic spheres made from phospholipids, the same fatty molecules that make up cell membranes. These phospholipids naturally arrange themselves in ...
-
Shining a Light on Drug Delivery: The Rise of Fluorescent Liposomes
Imagine tiny spheres, smaller than a red blood cell, glowing as they navigate the labyrinthine corridors of the human body. These aren't fireflies, they're fluorescent liposomes, a cutting-edge tool in the world of drug delivery and biomedical research. What are liposomes? Liposomes are microscopic bubbles made from phospholipids, the same fatty molecules that make up cell membranes. These ...
-
Preclinical Animal Models as A Resource to Explore Rare Diseases
Rare diseases, also known as orphan diseases, are a diverse group of disorders that affect a small percentage of the population. Due to their low prevalence and limited understanding, treating and finding cures for these conditions present significant challenges. However, preclinical animal models have emerged as invaluable resources for advancing research and unraveling the mysteries surrounding ...
By Protheragen
Need help finding the right suppliers? Try XPRT Sourcing. Let the XPRTs do the work for you