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Medchemexpress Colitis Equipment & Supplies

74 equipment items found

MedChemExpress - Model GDC0575 hydrochloride - 1196504-54-7

MedChemExpress - Model GDC0575 hydrochloride - 1196504-54-7

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
GDC0575 (ARRY-575) hydrochloride is a highly-selective and orally active Chk1 (IC50=1.2 nM) inhibitor. GDC0575 (ARRY-575) hydrochloride can be used for colitis-associated cancer (CAC) and colitis ...
CONTACT SUPPLIER

MedChemExpress - Model Oxazolone - 15646-46-5

MedChemExpress - Model Oxazolone - 15646-46-5

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
Oxazolone is a haptenizing agent that induces acute or chronic inflammation of the large intestine and is used to construct models of colitis. Oxazolone can cause Th1/Th2-dependent colitis with weight loss and diarrhea. Oxazolone-induced inflammation can be mitigated by neutralizing anti-IL-4 or anti-TNF-α antibodies or decoy IL-13R2-α-FC ...
CONTACT SUPPLIER

MedChemExpress - Model Vedolizumab (anti-a4ß7-integrin) - 943609-66-3

MedChemExpress - Model Vedolizumab (anti-a4ß7-integrin) - 943609-66-3

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
Vedolizumab (anti-α4β7-integrin) is a humanized IgG1 monoclonal antibody that targets the α4β7 integrin for the treatment of ulcerative colitis and Crohn's ...
CONTACT SUPPLIER

MedChemExpress - Model Vedolizumab - 943609-66-3

MedChemExpress - Model Vedolizumab - 943609-66-3

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
Vedolizumab is a humanized IgG1 monoclonal antibody that targets the α4β7 integrin for the treatment of ulcerative colitis and Crohn's ...
CONTACT SUPPLIER

MedChemExpress - Model Izencitinib - 2051918-33-1

MedChemExpress - Model Izencitinib - 2051918-33-1

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
Izencitinib (TD-1473) is an orally active, non-selective and gut-restricted JAK inhibitor. Izencitinib (TD-1473) can be used in the study for ulcerative ...
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MedChemExpress - Model Neihulizumab - 2158362-38-8

MedChemExpress - Model Neihulizumab - 2158362-38-8

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
Neihulizumab can be uesd for steroid-refractory acute graft-versus-host-disease (SR-aGVHD), psoriasis, psoriatic arthritis and ulcerative colitis ...
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MedChemExpress - Model Dextran sulfate sodium salt (MW 5000) - 9011-18-1

MedChemExpress - Model Dextran sulfate sodium salt (MW 5000) - 9011-18-1

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
Dextran sulfate sodium salt (MW 5000) is a polymer of anhydroglucose with a molecular weight of 5000. Dextran sulfate sodium salt (MW 5000) can be used to induce acute colitis and cause apoptosis of colonic epithelial cells in mice. The concentration dose used in the study was 5% (in feed, w/w). The sulfated polysaccharide dextran sulfate is also an effective inhibitor of HIV. ...
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MedChemExpress - Model Tussilagone - 104012-37-5

MedChemExpress - Model Tussilagone - 104012-37-5

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
Tussilagone, a major active component in Tussilago farfara, has anti-inflammatory effect. Tussilagone ameliorates inflammatory responses in dextran sulphate sodium-induced murine colitis. Tussilagone inhibits the inflammatory response and improves survival in cecal ligation and puncture (CLP)-induced septic ...
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MedChemExpress - Model Amelenodor - 2389235-01-0

MedChemExpress - Model Amelenodor - 2389235-01-0

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
NX-13 results in lower inflammation and responses in inflammatory bowel disease. NX-13 can be used for the research of crohn's disease and ulcerative ...
CONTACT SUPPLIER

MedChemExpress - Model Sulfasalazine-d4 - 1346606-50-5

MedChemExpress - Model Sulfasalazine-d4 - 1346606-50-5

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
Sulfasalazine-d4 is the deuterium labeled Sulfasalazine. Sulfasalazine (NSC 667219) is an anti-rheumatic agent for the research of rheumatoid arthritis and ulcerative colitis. Sulfasalazine can suppress NF-κB activity. Sulfasalazine is a type 1 ferroptosis ...
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MedChemExpress - Model Oroxylin A - 480-11-5

MedChemExpress - Model Oroxylin A - 480-11-5

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
Oroxylin A inhibits the IL-6/STAT3 pathway and NF-κB signaling, inhibits cell proliferation and induces apoptosis. Oroxylin A inhibits colitis-related ...
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MedChemExpress - Model Dextran sulfate sodium salt (MW 4500-5500) - 9011-18-1

MedChemExpress - Model Dextran sulfate sodium salt (MW 4500-5500) - 9011-18-1

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
Dextran sulfate sodium salt (MW 4500-5500) is a polymer of anhydroglucose with a molecular weight of 4500-5500. Dextran sulfate sodium salt (MW 4500-5500) can be used to induce acute colitis and cause apoptosis of colonic epithelial cells in mice. The recommended molecular weight in the study is 5000 (HY-116282) and the use concentration is 5% (in feed, W/W). The sulfated ...
CONTACT SUPPLIER

MedChemExpress - Model Tetracosactide acetate - 60189-34-6

MedChemExpress - Model Tetracosactide acetate - 60189-34-6

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
Tetracosactide acetate is a synthetic peptide stimulating the release of corticosteroids such as cortisol from the adrenal gland. Tetracosactide acetate is currently used for the research of ulcerative colitis and Crohn's disease, juvenile/adult rheumatoid arthritis and ...
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MedChemExpress - Model PAD-IN-2 - 2304852-21-7

MedChemExpress - Model PAD-IN-2 - 2304852-21-7

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
PAD-IN-2 can be used in the research of auto-immune diseases and cancers, such as rheumatoid arthritis, vasculitis, systemic lupus erythematosis, cutaneous lupus erythematosis, ulcerative colitis, cystic fibrosis, asthma, multiple sclerosis and ...
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MedChemExpress - Model Tetracosactide - 16960-16-0

MedChemExpress - Model Tetracosactide - 16960-16-0

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
Tetracosactide (Tetracosactrin) is an analogue of adrenocorticotrophic hormone (ACTH), Tetracosactide can stimulate the release of corticosteroids such as cortisol from the adrenal gland. Tetracosactide is currently used for the research of ulcerative colitis and Crohn's disease, juvenile/adult rheumatoid arthritis and ...
CONTACT SUPPLIER

MedChemExpress - Model Mirikizumab - 1884201-71-1

MedChemExpress - Model Mirikizumab - 1884201-71-1

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
By inhibiting the binding of IL-23 to IL-23R, Mirikizumab modulates the immune response and holds potential for research in ulcerative colitis and Crohn's ...
CONTACT SUPPLIER

MedChemExpress - Model Eldelumab - 946414-98-8

MedChemExpress - Model Eldelumab - 946414-98-8

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
Eldelumab can be used in studies of autoimmune and auto-inflammatory diseases such as rheumatoid arthritis, ulcerative colitis and crohn's ...
CONTACT SUPPLIER

MedChemExpress - Model Hydrocortisone hemisuccinate - 2203-97-6

MedChemExpress - Model Hydrocortisone hemisuccinate - 2203-97-6

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
Hydrocortisone hemisuccinate inhibits the bioactivity of IL-6 and IL-3 with IC50 values ​​of 6.7 and 21.4 μM, respectively. Hydrocortisone hemisuccinate can be used in the study of ulcerative colitis (UC) and recurrent oral ...
CONTACT SUPPLIER

MedChemExpress - Model Selnoflast - 2260969-36-4

MedChemExpress - Model Selnoflast - 2260969-36-4

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
Selnoflast is a potent inhibitor of IL-1β release stimulated by NLRP3 activation in human Alzheimer's disease (AD) monocyte-derived macrophages. Selnoflast is promising for research of AD and systemic inflammatory diseases, such as ulcerative colitis and chronic obstructive pulmonary ...
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MedChemExpress - Model 2'-Fucosyllactose - 41263-94-9

MedChemExpress - Model 2'-Fucosyllactose - 41263-94-9

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
2'-Fucosyllactose (2'-FL) is an oligosaccharide that could be derived from human milk. 2'-Fucosyllactose regulates the expression of CD14, alleviates colitis and regulates the gut microbiome. 2'-Fucosyllactose stimulates T cells to increase IFN-γ production and decreases IL-6, IL-17, and TNF-α production of ...
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