NBT - Navigated Brain Therapy System for Alleviating Chronic Neuropathic Pain Relief - Medical / Health Care - Clinical Services
At Nexstim we are using decades of scientific research to help alleviate drug-resistant brain diseases and disorders. As the world’s leading company combining TMS with 3D brain imaging, we offer a powerful noninvasive technique for the relief of chronic, refractory neuropathic pain.
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Despite recent therapeutic advances, more than half of patients with neuropathic pain still experience unsatisfactory pain control. It is widely believed that modulating neural activity in the motor cortex also modulates pain perception. Targeting rTMS, repetitive TMS, to the motor cortex region has achieved a clinically-meaningful response in a significant proportion of patients with chronic, unilateral neuropathic pain.
Growing and converging evidence suggests that the motor system becomes integrated with the complex processing of nociceptive signals. In patients with amputated limbs, part of the primary motor cortex becomes redundant for its prior tasks, while also being deprived of the sensory feedback. When a critical role of the motor cortex, that of suppressing excessive sensory input into the thalamus and inducing descending pain modulation, is compromised, spontaneous pain may result.