Pre-Clinical Technology Companies
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Technologybased in Ness Ziona, ISRAEL
Science in Action (SIA) is a boutique preclinical contract research organization (CRO) founded in 2010 by immunologist Raanan Margalit. SIA is GLP-accredited for toxicology studies in multiple areas. SIA has extensive experience in tailor-made ...
Clinical & Regulatory Support
SCOPUS is a Clinical Arm of “Science in Action” research organization that offers a broad range of clinical development services in all stages and aspects of study design. Our scientific background and “hands on” experience ...
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Technologybased in Graefelfing, GERMANY
SIRION Biotech started its business in 2005 in Munich, with the goal of sparking a new generation of viral vector technologies for cell and gene therapy, and vaccination development. This meant building novel, all-encompassing viral vector platforms ...
Sirion - Lentivirus Design & Production
Engineered Lentivirus vectors for gene expression and knockdown. Lentivirus vectors are the method of choice whenever a fast, efficient and cost-effective generation of stable cell models is required. SIRION Biotech’s custom lentivirus service ...
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Technologybased in Marseille, FRANCE
Neuron Experts is a Contract Research Organization (CRO) specialized in the study of neuro-active compounds. The company uses its own tests based on primary neuronal cell cultures modeling neurodegenerative diseases and neuronal impairment-induced ...
Advisory Services
Advice in the preclinical development of new neuro-active compounds. The Neuron Experts team (operational and scientific) provides support and advice in your R&D programs and also in the development of new molecules in specific disease ...
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Technologybased in Toronto, ONTARIO (CANADA)
Zucara Therapeutics is developing the first once-daily therapeutic to prevent hypoglycemia (low blood sugar) in people with diabetes. This pre-clinical technology is directed at regulating a hormone in the pancreas called somatostatin which in Type ...
Zucara - Hypoglycemia Technology
Zucara Therapeutics is developing ZT-01, a first-in-class, once-daily therapeutic to prevent insulin-induced hypoglycemia in patients using insulin therapy. ZT-01 is designed to inhibit somatostatin, a pancreatic hormone that impairs the glucagon ...
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Technologybased in San Diego, CALIFORNIA (USA)
Lorem Cytori is committed to providing meaningful and quality therapeutic options with broad utility that benefit patients and healthcare providers around the world. Whether it’s advancing our product and technology pipeline, performing clinical ...
Cytori - Cell Therapy Technology
Cytori is developing cell therapies that harness the unique attributes of living cells that are present in an adult human patient’s own adipose (fat) tissue, also known as Adipose-Derived Regenerative Cells ...
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Technologybased in Verona, ITALY
At Sibylla Biotech, we face the complexity of drug discovery with the power of an innovative approach for meeting unmet medical needs. Born out of a scientific challenge, the PPI-FIT protocol (Pharmacological Protein Inactivation by Folding ...
Model KRAS and Cyclin D1 (CCND1) - Proteins
We are currently working on the hit-to-lead process for KRAS and Cyclin D1 (CCND1) proteins in the biology ...
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Technologybased in Wuerzburg, GERMANY
At veriNOS Pharmaceuticals, we focus on the clinical development of a drug that specifically inhibits a defined cascade that is relevant and common in different disease settings. The activation of iNOS with subsequent excessive production of cell ...
Ronopterin - Selective Inhibitor of Inducible Nitric Oxide Synthase (iNOS)
Ronopterin is an allosteric inhibitor of inducible NO synthase (iNOS) that rapidly decreases the excessive production of NO resulting from acute overactivation of this enzyme. Ronopterin has no significant effect on the physiological production of ...
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Technologybased in Pittsburgh, PENNSYLVANIA (USA)
Apollo Neuroscience is pioneering a new category of wearable technology that actively improves health, using touch therapy to promote stress resilience, sleep, focus, recovery, and more. We believe that the human body is powerful, resilient, and has ...
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Technologybased in Oxford, UNITED KINGDOM
Vaccitech is a clinical stage T cell immunotherapy and vaccine company developing products to treat and prevent infectious disease and cancer. The company’s proprietary heterologous prime-boost platform comprises Chimpanzee Adenovirus Oxford ...
Vaccines and T cell Immunotherapies Technology
The patented Vaccitech adenovirus vectors are known as chimpanzee adenovirus Oxford 1 and 2 (ChAdOx1 and ChAdOx2), and are in the group E simian adenovirus family, similar to the widely-studied chimpanzee adenovirus 63. These viruses have been ...
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Technologybased in Vancouver, BRITISH COLUMBIA (CANADA)
Zymeworks Inc. is a publicly listed (NYSE: ZYME), clinical-stage, biopharmaceutical company dedicated to the discovery, development, and commercialization of next-generation multifunctional biotherapeutics, initially focused on the treatment of ...
Zanidatamab - Bispecific Antibody
Zymeworks’ lead product candidate, zanidatamab, is a HER2-targeted bispecific antibody developed using Zymeworks proprietary Azymetric platform. Zanidatamab is currently being evaluated in global Phase 1, Phase 2 and pivotal clinical trials as ...
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Technologybased in Wien, AUSTRIA
BlueSky Immunotherapies GmbH (Ltd.) is a clinical-stage biotech company. The company’s business is based on its own proprietary, novel technology platform for interferon-inducing viral vectors (delNS). Interferons have immunostimulatory and ...
BlueSky - Interferon-inducing Viral Vectors (delNS)
The high level of interferon induced by the delNS vector activates immunological defence reactions against cancer. It also stimulates the production of antiviral ...
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Technologybased in Cambridge, MASSACHUSETTS (USA)
Sumitomo Pharma Oncology, Inc. is a developer of novel cancer therapeutics based in the U.S. and a wholly owned subsidiary of Sumitomo Pharma Co., Ltd. This U.S. entity, together with the oncology research and development teams in Japan, Cancer ...
Sumitomo - Model TP-1287 - Investigational Oral CDK9 Inhibitor
TP-1287 is an investigational oral CDK9 inhibitor that has shown favorable oral bioavailability in preclinical models. TP-1287 is enzymatically cleaved, yielding the active moiety, a potent inhibitor of CDK9.35 Inhibiting CDK9 is thought to ...
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Technologybased in Carlton South, AUSTRALIA
Chimeric Therapeutics is a clinical stage cell therapy company focused on bringing the promise of cell therapy to life for more patients with cancer. We believe that cellular therapies have the promise to cure cancer not just delay disease ...
Chimeric - Model CHM 2101 (CDH17 CAR T) - T Cells for Derived Autologous Therapies
CHM 2101 (CDH17 CAR T) is an optimized 3rd generation CAR T cell therapy that is the first to target ...
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Technologybased in Abingdon, UNITED KINGDOM
Thermally Stable Needle Free Solid Dose Vaccines. Enesi Pharma is developing next-generation vaccination products targeting infectious diseases and emergent threat pathogens enabled by its ImplaVax technologies. These diseases affect millions of ...
Enesi ImplaVax - Enabled Vaccination Technology
We are focused on the development of the next-generation of vaccination products targeting serious diseases, using our proprietary ImplaVax® solid dose formulation and needle-free delivery ...
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Technologybased in Rockville, MARYLAND (USA)
Since the treatment of our first oncology patient in 2015, AbelZeta has been able to build best-in-class and best-in-disease potential pipeline, leading to the licensing of two CD20-directed autologous CAR-Ts to Janssen Biotech in 2023. Our goal is ...
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Technologybased in Rixensart, BELGIUM
CuraVac is a clinical-stage biotech company developing the medical and commercial potential of a revolutionary technique for the production of specific Therapeutic Vaccines for the treatment of autoimmune diseases. The company was founded by a ...
Autoimmune Diseases Services
Autoimmune diseases are conditions in which one’s immune system mistakenly turns against parts of the body as if they were harmful foreign cells. In response to an unknown trigger that may be environmental or genetic in nature, the immune ...
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Technologybased in Nangang Distric, TAIWAN
We are a clinical-stage specialty pharmaceutical company dedicated to the development and commercialization of best-in-class novel nanomedicines that combine our proprietary lipid-assembled drug delivery platform with approved active pharmaceutical ...
NanoX - Model TLC178 - Anticancer Drug Vinorelbine
TLC178 is our proprietary NanoX™ formulation of the anticancer drug vinorelbine, developed for the treatment of rhabdomyosarcoma (RMS), a rare form of soft tissue sarcoma that most frequently occurs in ...
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Technologybased in Boston, MASSACHUSETTS (USA)
We can create human tissues and organs using cells from our own bodies, paving the way to make us our own organ donors, reducing organ rejection and solve the problem with lack of donors. We can save lives with faster and more accurate methods for ...
BICO - Model spheroONE - Single Large-Particle Sorter and Dispenser
Automated sorting and isolation of single spheroids and organoids. A game-changer in drug screening and other applications where standard 3D models will gradually replace traditional animal models. spheroONE is an innovative single large-particle ...
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Technologybased in Poway, CALIFORNIA (USA)
VetStem Biopharma has endeavored to improve the lives of animals through regenerative medicine. As the first company in the United States to provide an adipose-derived stem cell service to veterinarians for their patients, VetStem pioneered the use ...
Stem Cell Clinical Trials for our Human Friends with OA
Since 2003, VetStem has been providing treatments for animals: Over 17,000 treatments for 30 difference species. Last year, the constant requests and pressure from veterinary colleagues and pet owners convinced our team to spin out a human stem cell ...
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Technologybased in Tokyo, JAPAN
At Olympus, we are committed to Our Purpose of making people’s lives healthier, safer and more fulfilling. As a global medical technology company, we partner with healthcare professionals to provide best-in-class solutions and services for early ...
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