Medical Drugs Articles
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Application of refractable nanocomposite on cell based therapy in central nervous system
Quantum Dots (QDs) are nano–particles carrying high stability fluorescence to follow the grafted cells which can be used in investigating the movement of cells and understanding the organogenesis of stem cells during development and wound repair processes in adulthood. For its easy acquirement and bypassing moral ethical issues, it makes the human adipose derived stem cells an attractive, ...
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Improving drug loading efficiency and delivery performance of micro– and nanoparticle preparations through optimising formulation variables
In this report, we briefly introduce our recent studies related to drug delivery systems using biodegradable materials, PLGA, PLA or chitosan to prepare submicroparticles or microparticles for carrying vaccine, protein or small molecule drugs. These preparations were prepared by spray dried or solvent extraction methods. In addition, liposomal formulations containing various lipids and pegylated ...
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Pharmaceutical blister packaging measured using WVTR and OTR instruments - Case Study
Since 1967 Tekni-Plex, Inc, has provided solutions for innovative packaging and tubing products. For their clients in the pharmaceutical and medical industries, the company has specialized in the development and manufacture of blister films offering superior barrier against ingress and egress of moisture and oxygen. In 2011 Tekni-Plex set up a Global Technology Center in Holland, Ohio, where ...
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A Commitment to Standards
An Interview with Philip Piqueira, Global Standards Leader for GE’s Industrial Solutions Business General Electric participates in standards development through its work on numerous committees and organizations. Philip Piqueira discusses why this business strategy and its continuance is crucial for GE. From your perspective as the global standards leader for General Electric’s ...
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Lot Acceptance Procedure Criteria
Providing Statistical Confidence to Pass Q. Lots are released based on comparing test results from a sample to lot acceptance procedure criteria. If a set of test results meets the lot acceptance procedure criterion, how can I be assured that another sample from the lot would also pass the criterion? A: Companies use lot acceptance procedures to release a lot. Test results from a sample are ...
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Effects of 17α‐ethynylestradiol, fluoxetine and the mixture on life history traits and population growth rates in a freshwater gastropod
Pharmaceutical and personal care products (PPCPs), some of which have endocrine disrupting effects at environmentally relevant concentrations, have been detected in many surface waters. We evaluated the effects of two common endocrine disrupting PPCPs on the life history traits of the snail, Physa pomilia, using a life table response experiment with snails raised in environmentally relevant ...
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Delta-T increased at biopharmaceutical manufacturing facility case study
The cooling towers at a biopharmaceutical manufacturing company in the Midwest had become packed with scale. The severe scaling resulted in the inability of the towers to maintain any cooling capacity during extremely hot summer temperatures. RYDLYME approach 660 gallons circulated for 6 hours. RYDLYME results Cleaning resulted in Delta-T increase of 14°F! The gains in efficiency ...
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Nitrogen analysis of pharmaceutical excipients
Customer: Butterworth Laboratories, United Kingdom Wilh nearly 40 years' experience, Butterworth Laboratories remains an independent UK con¬tract analytical service providing Method Development, Method Validation, Stability Testing and OC Testing to the pharmaceutical, medical device and chemical industries. They work in part¬nership with clients who not only recognize expertise in ...
By BUCHI
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Pharmaceutical / Personal care product manufacturer promotes quality standards
Challenge Pharmaceuticol manufacturers demand high qualify water with the fewest dissolved solids possible, to promote product consistency. A Canadian manufacturer of pharmaceutical/personal core products was looking to maintain water quality specifications to promote product consistency and improve product shelf life. First the source water for the manufacturing plont comes from a municipal ...
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Pharmaceutical and Medical Sector Waste Review Service
Pharmaceutical manufacturing plants generate a variety of waste streams throughout the production, supply and organisational processes. While the day-to-day activities are similar from one plant to the next, the actual processes used in pharmaceutical manufacturing vary widely. The pharmaceutical industry is highly competitive and many organisations are often unwilling to reveal details that ...
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Capability portfolio for the initial phase of internationalisation of emerging economy firms: a study in the Indian pharmaceutical industry
This paper analyses the internationalisation experiences of seven firms in the Indian pharmaceutical industry and identifies the portfolio of capabilities required in the initial phase of internationalisation. It traces the priorities, simultaneity and sequence in the capability development process and identifies the differences between early and late internationalisers. It notes that studies so ...
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Project - Turnkey water system for Aesica Pharmaceuticals
In 2013 Aesica, supplier of Active Pharmaceutical Ingredients (API) and finished dose manufacturing to the pharmaceutical industry, unveiled its new high capacity manufacturing facility specifically built to produce a solid dose medication for treating Type 2 diabetes in adults. Puretech supplied the turnkey water system for the facility, including pre-treatment, 3mr/hr Oasys, 10,000 litre ...
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Ultrasonic Liposome Preparation for Pharmaceuticals and Cosmeceuticals
Liposomes works as carriers for active agents. Ultrasound is an effective tool to prepare and form the liposomes for the entrapment of active agents. Before encapsulation, the liposomes tend to form clusters due to the surface charge-charge interaction of phospholipid polar heads (Mickova et al. 2008), furthermore they have to be opened. By way of example, Zhu et al. (2003) describe the ...
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Strategic alliance: case study in competitive positioning
The case seeks to identify some of the issues encountered in the development and growth of a family–owned firm in the pharmaceutical business in Lima, Peru. Having overcome the initial challenges of its establishment, the company has become a visible and viable competitor in the Peruvian market and is poised to expand in cross border markets by exploring the prospect of a strategic alliance with ...
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Intellectual property management practices at small and medium-sized enterprises
Small and medium-sized enterprises (SME) contribute to innovation and economic growth, despite their resource shortages and lack of professional intellectual property (IP) management practices. Drawing on social practice theory and combining insights from recent scholarship on IP strategies and its management, this paper examines the cases of three pharmaceutical SME providing insights into how ...
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Estimating production technical efficiency for the US biopharmaceutical industry
This article estimates the production technical efficiency of pharmaceutical companies and biotechnology companies under heterogeneous technologies. We employ metafrontier analysis to estimate the production metafrontier technical efficiency during the period 1989–2007. When using traditional stochastic frontier analysis, the results show that the technical efficiency of the biotechnology ...
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Impacts of pH-dependent metal speciation on the decomposition of triclosan by sulfate radicals
The presence of triclosan (TCS) in water resources has drawn significant attention due to its endocrine disruption potential. Sulfate radicals (SRs), generated particularly by the metal-mediated activation of peroxymonosulfate (PMS), have been proposed to effectively decompose TCS and many other pharmaceuticals and personal care products. In spite of its significance for understanding the ...
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Long–term value creation in the pharmaceutical sector: an event study analysis of big pharma stocks
We investigate the drivers of value creation in big pharmaceutical firms. We use a unique dataset of a total of 2,200 news items on research and development (R&D) progress announcements and dividend news of 25 largest pharmaceutical companies for the period 1998–2010. Our findings affirm the role of successful R&D as a driver of value creation in the long–run. This long term view of value ...
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