Urology Articles
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Hypoglycemic Functional Factors in Natural Products and Their Mechanisms of Action
Diabetes is a common clinical disease, and with the improvement of living standards, an increase in the number of obese people, and the intensification of aging populations, the incidence of diabetes is increasing year by year. Diabetes has various types and requires long-term treatment. Antidiabetic drugs are essential for people with the disease. These drugs can be classified into insulin ...
By BOC Sciences
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An Emerging Aim: ADC Target Protein - Nectin-4
The biologics license application (BLA) has been accepted for Enfortumab Vedotin for the treatment of locally advanced or metastatic urothelial carcinoma in patients who have previously received PD-1/PD-L1 inhibitors and platinum-containing chemotherapy. Enfortumab Vedotin is the first domestically submitted targeted antibody-drug conjugate that specifically targets Nectin-4. Enfortumab ...
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Bladder management practice for spinal cord injury patients
The spinal cord is to relay messages between the brain and the rest of the boy. When spinal cord injury happens the body may lose some essential functions if the nerves can’t communicate with the brain. Inadequate bladder management of spinal cord injury (SCI) results in medical complications, psychological stress and even mortality. Frequent leakage of urine causes soiling of clothes ...
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Research Progress of Tetrahydrocurcumin
Tetrahydrocurcumin (THC), as the most active and main metabolite produced in the metabolism of curcumin in vivo, can be isolated from the cytoplasm of the small intestine and liver after curcumin administration in human or mouse. Tetrahydrocurcumin can effectively inhibit tyrosinase, inhibit the generation of Oxygen Free Radicals and scavenge the formed free radicals. It has obvious antioxidant ...
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Project - Horizon 2020 EIC
This project has received funding from the European Union's Horizon 2020 research and innovation programme under grant agreement No. ...
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Top-Down Proteomics vs. Bottom-Up Proteomics
Protein research is one of the most challenging topics in analytical chemistry. Initial protein research focused on developing techniques capable of isolating and identifying major sequences (or portions) of proteins. The Edman degradation of peptides is a revolutionary method to identify the main amino acid sequence of a peptide. In addition, the whole sequence of proteins can be determined by ...
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Movember Together: How Paige, University of Oxford, and Prostate Cancer UK Are Working to Change the Prostate Cancer Experience
Movember is an annual initiative where men from around the globe grow mustaches to raise awareness for men’s health causes, including mental health and suicide prevention, testicular cancer, and prostate cancer. Through events, fundraising, and using mustaches as a light-hearted starting point for important conversations, the movement supports men in taking charge of their health to live ...
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Value of BWT Measurement in Bladder Scanner
Being the first bladder scanner in the world which can measure BWT bladder wall thickness, M5 makes it possible that BWT can be monitored easily and quickly on daily basis. This feature fosters research on coorelation between BWT and different urological diseases. During the interview with Dr. Xu Kexin from Peking University People's Hospital whose team has been using M5 for about one year, we ...
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Variability in Nerve Location During da Vinci Prostatectomy
Objectives Preservation of nerves during da Vinci prostatectomy (dVP) has been clinically proven to be critical to preservation of urinary function and surgeon perception has been shown to be a poor predictor of nerve location during dVP. Despite this evidence, opinions still vary on the ability of surgeons to use anatomic landmarks to accurately identify these nerves during dVP and to ...
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Intraoperative Identification and Monitoring of the Somatic Nerves Critical to Potency Preservation during da Vinci Prostatectomy
Background Since Walsh and Donker first introduced the anatomic nerve-sparing technique for retropubic radical prostatectomy1 (RRP) in the treatment of clinically localized prostate cancer, the importance of minimizing damage to the neurovascular bundle (NVB) has been recognized as a critical element for the preservation of potency and urinary continence post-prostatectomy. Although originally ...
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High-resolution Map of Somatic Periprostatic Nerves
Objective To generate a high-resolution map of periprostatic somatic nerves. Periprostatic nerves are at risk of injury during radical prostatectomy; this study aimed to establish the location of somatic nerves with respect to the prostate and the neurovascular bundle. Materials and Methods Hemiprostates from patients in whom a wide local excision was performed were evaluated. Representative ...
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What is Urine Flow Rate Test?
What is urine flow rate test? You may be unfamiliar with the term urine flow rate or urinary flow rate, which is a common medical term in urology. Put it simply, the rate of urine flow measures how fast urine flows, how much it flows out, and how long it takes. It is expressed in ml/s. Urine flow rate test is done mainly when the following symptoms appear: bladder residual urine increase ...
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What is the difference between infection and disease?
Disease-causing microbes are often found in the human microbiome. So, when does the presence of pathogenic microbes indicate an infection? And when does the presence of infection explain disease? What is an infection? What is a disease? A disease associated with microbes is the outcome of interaction(s) between a microbe(s) and its host in which the host suffers some sort of damage. ...
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The use of auto expanding Allium Ureteral Stent in the endourological management of UPJ stenosis and ureteric strictures: our experience and preliminary results
Introduction: The aim of the study is to evaluate the efficacy of the auto expanding Allium® Ureteral Stent (URS) in the endourological management of UPJ stenosis and ureteric ...
By Allium Ltd
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Allium TM TPS—A New Prostatic Stent for the Treatment of Patients with Benign Prostatic Obstruction: The First Report
Introduction: Several prostatic stents were developed in the last three decades, none of which were able to provide a real alternative in patients unfit or unwilling to undergo classical prostatic surgeries. In this study, we report the results of the use of a newly developed prostatic stent—the Allium™ Triangular Prostatic Stent (TPS). Patients and Methods: The Allium TPS is a ...
By Allium Ltd
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Nanostics Announces Study Data Supporting ClarityDX Prostate as a Reflex Test to Predict Clinically Significant Prostate Cancer
Real-world data shows that at a 94% sensitivity level for prostate cancer ClarityDX Prostate® is 147% more specific than the PSA test for predicting clinically significant prostate cancer. Using ClarityDX Prostate® as a reflex test vs. PSA test alone could have resulted in 37% fewer unnecessary biopsies. The clinical study recruited men from two sites in Alberta, Canada, and one site ...
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Stream 10 — Urogynaecology (FC10) - Case Study
Introduction Validated questionnaires and urodynamic studies are used to diagnose and evaluate female lower urinary tract symptoms (FLUTS) including urinary incontinence and or urgency. Objective To validate and use Sinhata translations of the International Consultation on Incontinence Modular Questionnaire for FLUTS (ICIQ-FLUTS) and the King's Health Questionnaire ...
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How The Pelvic Floor Therapy System Can Help Improve your Health
The pelvic floor physical therapy system is a therapeutic method that uses physical therapy concepts to recondition the pelvic floor muscles in a systematic, effective, and safe manner. The treatment’s purpose is to increase the strength and function of the pelvic floor muscles, as well as to relieve discomfort, weakness, and inefficiency. A qualified physical therapist accesses the muscles ...
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Validation of a two-gene mRNA urine test for detection of high-grade prostate cancer in German men.
Organizations Martini-Klinik Prostate Cancer Center and Department of Urology, University Hospital Hamburg-Eppendorf, Hamburg, Germany, MDxHealth, B.V., Nijmegen, Netherlands, MDxHealth, Inc., Irvine, CA, Mathematical Modeling, Statistics and Bioinformatics, Ghent University, Ghent, Belgium, Martini-Klinik Prostate Cancer Center, University Hospital Hamburg-Eppendorf, Hamburg, Germany Abstract ...
By MDxHealth
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Titanium but not just titanium
Titanium and its alloys have many advantages as surgical implant materials, such as low density, high strength, good toughness, good biocompatibility, non-toxicity, low elastic modulus, good corrosion resistance, and low X-ray absorption rate Etc., thus occupying an increasingly important position in medical metal materials. Titanium and its alloys can be used for the repair and replacement of ...
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