Model CD160TM - Natural Killer Cells
CD160TM NK cell boost using CD160-TM specific monoclonal antibodies. Natural Killer cells (NK) represents a cell population involved in the cancer cell destruction through recognition of tumor cells followed by cell killing through cell-cell contact cytotoxicity. High rate of NK cell infiltration in the tumor microenvironment has been correlated with increased survival and better prognosis in several cancers. The boost of NK cell cytotoxic function locally in the tumor can increase the rate of cancer cell destruction and trigger an improved immune response to the tumor. CD160-TM is a novel NK cell activating receptor involved in their cytotoxic activity. Alderaan Biotechnology is developing antibodies against CD160-TM in order to boost the rate of cancer cell destruction in the tumor by hyper activating CD160-TM positive NK cells.
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