Orgentec - Model ORG 200 - ANA Detect for ELISA-Based Screening test
From Alegria and Alegria 2 - for Automated Laboratory Diagnostics
ANA Detect is an ELISA-based screening test for the quantitative determination of autoantibodies (IgG) against components of the cell nucleus and the cytoplasm in human serum or plasma. Some antinuclear antibodies (ANA) serve as markers for the diagnosis of rheumatic inflammatory connective tissue diseases like lupus erythematosus (SLE), Sjögren’s syndrome, Sharp syndrome (mixed connective tissue disease), polymyositis/dermatomyositis, and progressive systemic scleroderma (PSS) with CREST syndrome. Each individual well in the ANA Detect test is coated with 26 human, recombinant, highly purified antigens. This combination guarantees high diagnostic sensitivity with excellent specificity and is the first choice in cases of suspected systemic autoimmune disease. Patient samples that test positive with ANA Detect should subsequently be tested with the respective single ELISA tests from ORGENTEC.
Specifications
- Product Number: ORG 200
- Tests: 24 Alegria® strips
- Calibration: CDC sera, WHO Wo/80 reference
- Calculation: qualitative
- Cut-off: Index > 1.2
- Coating: centromere B, histone proteins H1, H2A, H2B, H3, H4, histidyl-tRNA synthetase (Jo-1), mononucleosomes, Pm-Scl-100, polynucleosomes, RNP-A, RNP-C, RNP-70, RNP/Sm complex, Scl-70 protein (DNA topoisomerase I), SS-A 52 (Ro 52), SS-A 60 (Ro 60), SS-B (La), ssDNA , histone complex, Sm-BB, Sm-D, Sm-E, Sm-F, Sm-G, dsDNA
ORG 233 ORG 238 ORG 207 ORG 206 ORG 213 ORG 232 ORG 211 ORG 212 ORG 208 ORG 252 ORG 260 ORG 209 ORG 205 ORG 204G
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