Chronic Diseases Articles
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Hypoglycemic Functional Factors in Natural Products and Their Mechanisms of Action
Diabetes is a common clinical disease, and with the improvement of living standards, an increase in the number of obese people, and the intensification of aging populations, the incidence of diabetes is increasing year by year. Diabetes has various types and requires long-term treatment. Antidiabetic drugs are essential for people with the disease. These drugs can be classified into insulin ...
By BOC Sciences
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Scireq Softrestraint for Exposure Studies
Evaluating the stress related effects of various restraint methods in rodents Any restraining device used in an inhalation exposure set-up will be, by definition, restricting the subject’s ability to move. For nose-only inhalation set-ups, typical restraints are rigid, fully enclosed and include a metal or acrylic plunger forcing the subject forward and preventing the subject from ...
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Examining Models of Chronic Obstructive Pulmonary Disease (COPD) and their Application in Other Disease Frameworks
The field of medical science has long utilized disease models, which are systems simulating the progression and expression of a disease, to better understand various illnesses. These models facilitate the study of disease pathology, identifying underlying mechanisms, and developing potential treatments. In the context of respiratory diseases, numerous models have been developed, with a prominent ...
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Gene Therapy for Cystic Fibrosis
What is cystic fibrosis? Cystic fibrosis (CF) is a rare genetic disorder that affects the lungs, digestive system, and other organs. It is caused by mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene, which encodes a protein that regulates chloride ions transport across cell membranes. These mutations cause the CFTR protein to be either absent or not function ...
By Protheragen
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Examining Models of Chronic Obstructive Pulmonary Disease (COPD) and their Application in Other Disease Frameworks
The field of medical science has long utilized disease models, which are systems simulating the progression and expression of a disease, to better understand various illnesses. These models facilitate the study of disease pathology, identifying underlying mechanisms, and developing potential treatments. In the context of respiratory diseases, numerous models have been developed, with a prominent ...
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Overview of Diabetes: Prevalence Assessment, Treatment And Prevention
Diabetes is a chronic disease that affects more than 540 million people worldwide and is one of the leading causes of death and disability worldwide. In China, there are more than 114 million adults with diabetes, accounting for about a quarter of the world's diabetes patients. With the change of living and eating habits, diabetes has become the third major factor affecting human health after ...
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The Role of MMP-3: Insights into Disease Progression and Therapeutic Potential
The MMP Family Matrix metalloproteinases (MMPs) are a family of enzymes belonging to the metzincin superfamily. There are 23 different types of secreted or membrane-anchored endopeptidases in the human body. MMPs are capable of degrading ECM proteins such as collagen, gelatin, laminin, fibronectin, fibrinogen, elastin, and proteoglycans. They were once considered regulators of the extracellular ...
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Will Metformin Be Replaced By SGLT-2 Inhibitors
Metformin is a classic first-line hypoglycemic agent for patients with type 2 diabetes, and is an essential drug in combination regimenes. However, as the evidence is updated, the idea of drug selection for first-line treatment is changing. GLP-1 agonists and SGLT-2 inhibitors in combination with or without metformin (as required for glycemic management) have also been recommended by multiple ...
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How Healthcare is Being Transformed By Remote Patient Monitoring
It cannot be denied that the healthcare sector is evolving quickly due to development and technological advancements. The creation of remote patient monitoring (RPM) systems and apps is a result of this. Healthcare providers can remotely monitor and examine patient health data thanks to remote patient monitoring systems. This provides people with convenience and easy access to healthcare. ...
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How Health Apps and Devices are Changing the Way We Manage our Health
There has been a recent shift in how we approach health and well-being. We now have more control over our health and fitness thanks in large part to Remote Patient Monitoring (RPM) apps and equipment. Health applications and technologies are transforming how we manage our health, from tracking our everyday activities to monitoring our vitals and chronic illnesses. Health apps and devices are ...
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Evolutionary, Medical, and Clinical Applications of Whole Exome Sequencing
As we all know, proteins play important roles in human bodies since all physiologic events are related to the structural or mechanical functions of certain proteins. Studying the synthesis process of proteins is a way to study the etiology, pathophysiology, diagnosis, and treatment of certain diseases. The human genome contains approximately 3 billion base pairs of DNA. Among them, only about 30 ...
By CD Genomics
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The Health Effects of Probiotics on the Human Body
Probiotics are a type of active microorganisms that play a role by improving the balance of the host's intestinal microflora. They can produce definite health effects to improve the host's microecological balance and play a beneficial role. In 2001, the World Food and Agriculture Organization (FAO) and the World Health Organization (WHO) also defined probiotics as follows: Live bacteria that can ...
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Adenocarcinomas and Their Often Misleading Symptoms When Dyspepsia Is an Indication of Cancer - Case Study
Medical History Jane is a 40-year-old, married mother of two teenage boys. She teaches at the local elementary school and has been in good health for most of her life. She has no surgical history. Her most severe ailment up to this point has been the flu at age 27. Her students are first-graders; they are often difficult to control. She also experiences the normal stresses of raising ...
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Surgical Site Infection: Methods of Prevention & Tools for Predicting Risk - Case Study
Medical History A 55-year-old white male has degenerative arthritis of the knees. 10 months ago, the patient underwent total knee replacement on the left knee without complication. The surgical incisions had closed without signs of surgical site infection. At the time, he made a good recovery. He is fully functional and fully independent. Patient is a chain smoker with a wife and two children. He ...
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The Relationship Between Enzyme Function and Health
In the early 20th century, humans discovered vitamins, and then trace elements and minerals. It was only in the mid-1980s that humans realized the importance of enzymes. Nobel Prize in Physiology and Medicine Arthur Kornberg said: "For our lives, we can no longer find other substances as important as enzymes in nature." Enzymes control the entire body, and when enzymes function abnormally is ...
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Teleradiology in Covid-19
The start of coronavirus pandemic pushed limits of healthcare systems all over the world by causing thousands of deaths and the requirement of a huge quantity of healthcare resources. When WHO declared COVID19 as a pandemic, the whole world came to standstill. Half of the world population is confined to their home except for essential services. In the year 2016, when GOI announced ...
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Reading the language of nature: Applying AI-augmented algorithms to enriched metagenomic databases
With our current drive to preserve and maintain our planet in the midst of climate change, and even reach beyond its boundaries into space, having a better understanding of our world’s biological building blocks – proteins – is key. Proteins compose an essential part of our biological world – providing structural, enzymatic and other types of functions, in our human ...
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Huateng Pharma Develops Intermediates of Semaglutide For TD2
According to the latest IDF Diabetes map, the global prevalence of diabetes reached 10.5% in 2021, with 537 million adults living with diabetes. China has become a disaster zone for diabetes, with the largest number of adults with diabetes in the world. In the past 10 years (2011-2021), the number of people with diabetes in China increased from 90 million to 140 million, an increase of 56%. The ...
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Association between Diabetes Mellitus and chronic kidney disease with Muscle loss and weight loss
Muscle loss / muscle wasting is the condition in which, proteolytic systems for protein degradation are activated, while protein synthesis decreases, thereby resulting in muscle fiber shrinkage. This condition may be due age or might be due some chronic conditions like Diabetes mellitus (DM) or chronic kidney disease (CKD). Extreme muscle wasting often results in weight loss. Such a condition is ...
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NASA Studies - PEMF technology
The PEMF technology has been studied by NASA in a four-year, $3.5 million study, with very positive ...
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