Hypoxia Articles
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We put the O2 in WRKUT
Over the course of time, humankind has been continuously searching for methods to remain young, preserve their health and become more and more efficient in all aspects of their existence. Especially nowadays, in the fast-paced world that we all live in, it is important to maintain a balanced lifestyle and to prioritize the health of our bodies and minds. But do you really have the time to ...
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Development of a Bioartificial Vascular Pancreas
Abstract Transplantation of pancreatic islets has been shown to be effective, in some patients, for the long-term treatment of type 1 diabetes. However, transplantation of islets into either the portal vein or the subcutaneous space can be limited by insufficient oxygen transfer, leading to islet loss. Furthermore, oxygen diffusion limitations can be magnified when islet numbers are increased ...
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An NBA Superstar and Sleep Apnea: Shaq
Shaquille O’Neal: Sleep Apnea Shaquille O’Neal, also known as Shaq, is an NBA basketball player who played as a center throughout his career with six different teams and has been inducted into the NBA Hall of Fame. Born in Newark, NJ, Shaq started to play basketball at the Boys and Girls club and went to Louisiana State University. Now retired, Shaq works as a spokesman for brands ...
By BioSerenity
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Importance of hemodynamic monitoring during esophagectomy - Case Study
Background Esophagectomy for cancer involves two- or three-phase procedures, such as abdominal, chest and/or neck incisions, is more invasive than other types of gastrointestinal surgery, and is associated with high risk for postoperative morbidity. Because of this risk, perioperative management of circulatory conditions such as hypovolemic hypotension is especially important to avoid ...
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How Reduced Oxygen Delivery Devices are Used in the Military
The defence industry requires advanced technology and solutions for the unique, and often extreme conditions, in which people work. The military conducts scientific and technological research and officer training in high altitude environments with low oxygen levels. Thus, reduced oxygen delivery devices are necessary and widely used by various branches of the military, including the Air Force, ...
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InfraScan Inc. Announces Issuance of US Patents for Brain Diagnosis
Latest patents expand near infrared platform capabilities related to trauma and stroke diagnosis InfraScan, a medical device firm specializing in brain injury and stroke diagnostic products, announced today the issuance by the US Patent Office of three additional patents that cover internal bleeding, brain trauma and stroke detection technologies. The first patent for invention number US ...
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COVID-19 Clinical Report for Dead Infected Case
Clinical analysis of 25 novel coronavirus pneumonia deaths:asphyxia due to pulmonary mucus Pengpai news reporter Wu Yi Pengpai news ,February 29 On February 25, MedRxiv published a paper from Wuhan University People's Hospital, Clinical characteristics of 25 death cases infected with COVID-19 pneumonia: a retrospective review of medical records in a single medical center, Wuhan, China. The ...
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KTM - Save costs with self-produced medical oxygen
The Hospital of the Sisters of Mercy in Prague Puts its Trust in Self-Generated Oxygen Medical oxygen is used to treat patients in many areas at the Hospital of the Sisters of Mercy. For example, oxygen is used in a number of operating theatres and to treat hypoxia in drug addicts in the Czech Republic‘s only detoxification centre. Two oxygen generators made by the German company INMATEC ...
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Oxygen therapy for rheumatology
HBOT is a very effective adjunctive treatment for Rheumatoid Arthritis procedures Rheumatoid arthritis is a chronic inflammatory autoimmune disorder that can affect the lining of the joints and cause painful swelling that will result in the erosion of bones and the deformation of joints, which aggravated, leads to physical disabilities. As an autoimmune disorder, rheumatoid arthritis ...
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Oxygen therapy for neurology
A prematurely aged brain has suffered years of abuse from our ever-increasingly toxic environment and unhealthy lifestyles. There is extensive research that shows HBOT may have an effect in rejuvenating a patient’s brain by stimulating the production of new blood vessels. Increased oxygen in the blood flow will re-energize dormant cells in the brain and create new ones. Oxygen to ...
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Expression of phytoglobin affects nitric oxide metabolism and energy state of barley plants exposed to anoxia
Abstract Class 1 plant hemoglobins (phytoglobins) are upregulated during low-oxygen stress and participate in metabolism and cell signaling via modulation of the levels of nitric oxide (NO). We studied the effects of overexpression and knockdown of the class 1 phytoglobin gene in barley (Hordeum vulgare L.) under low-oxygen stress. The overexpression of phytoglobin reduced the amount of NO ...
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Increasing Cell Adherence with a Hypoxia Workstation
Abstract A major criticism of all-in-one workstations (sometimes known as incubated workstations or incubated glove boxes) over using traditional incubators and biosafety cabinets for cell culture is that the exposure to excessive vibration will affect cell growth and adhesion. Here we tested the cells’ capabilities to attach in a Baker Ruskinn SCI-tive hypoxia workstation as compared to a ...
By Baker
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Conditioning Media to Target Dissolved Oxygen Levels
Summary Hypoxia is defined as oxygen deficiency in cellular environments. Oxygen (O2) deficiency within in vivo environments is commonly linked to a wide range of co-morbidities, e.g., respiratory failure, Mycobacterium tuberculosis infection and other life threatening ailments (Reference Section; 2, 6). However, certain cell types thrive in low-O2 environments. Angiogenesis and tumor progression ...
By Baker
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Understanding and forecasting hypoxia using machine learning algorithms
This study's primary objective lies in short-term forecasting of where and when hypoxia may transpire to enable observing its effects in real time, focusing on a case study in Corpus Christi Bay (Texas). Dissolved oxygen levels in this bay can be characterized by three temporal trends (daily, seasonal, and long-term). To predict hypoxic events, these three mathematical trends are isolated and ...
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Effect of maternal obesity and passive smoking on neonatal nucleated red blood cells
Passive cigarette smoking and obesity during pregnancy are risk factors for adverse outcome in infant. Elevated umbilical cord neonatal nucleated red blood cells (NRBCs) have been suggested as a marker of intrauterine foetal hypoxia. Aim to demonstrate whether maternal risk factors during pregnancy are capable of elevating circulating NRBCs measured at birth. We compared the count of NRBCs in the ...
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Reactive oxygen species regulate hypoxia-inducible factor 1 differentially in cancer and ischemia
In exercise, as well as cancer and ischemia, hypoxia-inducible factor 1 (HIF1) transcriptionally activates hundreds of genes vital for cell homeostasis and angiogenesis. While potentially beneficial in ischemia, upregulation of the HIF1 transcription factor has been linked to inflammation, poor prognosis in many cancers, and decreased susceptibility of tumors to radiotherapy and chemotherapy. ...
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Reactive oxygen species regulate hypoxia-inducible factor 1 differentially in cancer and ischemia
In exercise, as well as cancer and ischemia, hypoxia-inducible factor 1 (HIF1) transcriptionally activates hundreds of genes vital for cell homeostasis and angiogenesis. While potentially beneficial in ischemia, upregulation of the HIF1 transcription factor has been linked to inflammation, poor prognosis in many cancers, and decreased susceptibility of tumors to radiotherapy and chemotherapy. ...
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Hypoxia and other environmental factors at high altitude
Besides hypoxia, high altitude settings are characterised by other peculiar environmental factors, such as cold and ultraviolet radiation. In addition, there are prevalent environmental changes driven mainly by human activity, including climate change in the highland Andes, and outdoor and indoor pollution. Also, poverty and childhood malnutrition are rampant in high altitude human settlements. ...
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Intermittent work at high altitude: a new epidemiological situation
A review of the epidemiological features of a new labour condition, namely, working intermittently at high altitude, is presented. A retrospective study was designed to compare mine employees living and working at 4,600 m and undergoing chronically intermittent exposure to high altitude with a similar group of workers at sea level, during 2 years. Overall 91,500 medical consultations were ...
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A microRNA signature of hypoxia
Recent research has identified critical roles for microRNAs in a large number of cellular processes, including tumorigenic transformation. While significant progress has been made towards understanding the mechanisms of gene regulation by microRNAs, much less is known about factors affecting the expression of these noncoding transcripts. Here, we demonstrate for the first time a functional link ...
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