In Vivo Models Applications
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Microscope System for Molecular imaging of cancer
Longitudinal imaging of pancreatic cancer. Monitor in a minimally invasive manner both tissue morphology and fibrosis (fluorescein) and cathepsin activity (Prosense® 680). A very thin probe (S 650) was used to monitor the pancreas of the same mouse over 9 months. ...
By Mauna Kea Technologies based in Paris, FRANCE.
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Clinicians - FIRE – A Flexible and Precise Molecular Probe Platform Expressly Designed for Cancer Surgeons
A critical factor in ensuring complete resection of a solid cancer tumor is the ability to determine where diseased tissue ends and healthy tissue begins. Our research, as well as our clinical collaborators, confirm that there is a pressing unmet clinical need: the ability to rapidly and globally assess the status of marginal tissue adjacent to a tumor while the patient is in the ...
By Akrotome Imaging, Inc. based in Cleveland, OHIO (USA).
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Cellframe Technology
Following extensive research and development, Biostage has evolved its technology to optimize the interaction of mesenchymal stem cells seeded on a biocompatible scaffold. Preclinical studies suggest that, once implanted, the scaffold seeded with the patient’s own cells signals the stem cell niche to guide the regeneration of a biological ...
By Biostage, Inc. based in Holliston, MASSACHUSETTS (USA).
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Medical solutions for vaccine platform sector
2A Pharma’s vaccine platform is based on mutated parvoviral particles consisting essentially of one protein. The particles contain no viral genome and are replicative defective and non-pathogenic. The particle capsid surface has repetitive, immunogenic sites, where peptides of interest can be inserted and allows us to generate monovalent or bivalent vaccines as required. Each peptide of interest will be presented 60 times on the capsid surface and both the innate and adaptive immune systems are activated to ...
By 2A Pharma ApS based in Aalborg Øst, DENMARK.
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In-Vivo Biomarker Drug for Lymphoma
Lymphoma is a cancer of the lymphatic system which can occur at any age, but it is one of the most common causes of cancer for children and young adults, between 15 and 24 years ...
By Zionexa based in Fishers, INDIANA (USA).
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In-Vivo Biomarkers for Breast Cancer
Breast cancer, most common cancer among ...
By Zionexa based in Fishers, INDIANA (USA).
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Microbiotica Solutions for Clinical Data and Sample Sets
Microbiotica is using best-in-class clinical data and sample sets coupled with its unrivalled microbiome profiling capability to progress best-in-class therapeutics and biomarkers. Microbiotica has programs in IBD, Immuno-oncology and Gut Epithelial Barrier Repair developing medicines and biomarkers based on microbiota. These programs start with deep metagenomic and culture-based analysis of patient samples and involve advanced bioinformatics and machine learning, to identify highly significant bacterial ...
By Microbiotica Limited based in Little Chesterford, UNITED KINGDOM.
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vitro 3D Blood Brain Barrier for Brain Blood Barrier
Kirkstall’s Quasi Vivo® system aims to establish and optimise a human in vitro 3D Blood Brain Barrier (BBB) in an effort to identify important mechanistic pathways for successful biomarker analysis, drug delivery and toxicity ...
By Kirkstall Ltd. based in York, UNITED KINGDOM.
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Acoustic Bioprinter for Bridging from Bench to Bedside
In vivo evaluation of sound-patterned endothelial cells. ...
By mimiX Biotherapeutics based in Biel/Bienne, SWITZERLAND.
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Compact MRI Systems for Anatomy and Morphology
In vivo soft tissue imaging for morphological characterization. 2D and 3D imaging can be performed quickly and easily for preclinical model ...
By Aspect Imaging Ltd. based in Nashville, TENNESSEE (USA).
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Medical solutions for point-of-care/use sector
The fast track to accurate results. Point-of-Care testing has become increasingly important in recent years as a patient-oriented or general close proximity testing method to generate rapid results. Especially in emergency medical care, where a quick diagnosis can be crucial, PoC has become indispensable. Our PoC devices are effectively decentralizing diagnostics, allowing rapid results basically anywhere at any time. Thus, this quick and close testing for markers of interest dramatically improves access, outcome, ...
By LRE Medical based in Noerdlingen, GERMANY.
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Highly customized aptamer discovery solutions for aptamers in neurological disease sector
More than 5 million people in the United States and an estimated 50 million people worldwide are living with Alzheimer’s disease. More than 10 million people worldwide are living with Parkinson’s. Brain tumors and tumors of the central nervous system are the most common form of cancer in children under 19 and the leading cause of cancer-related deaths in children under 14 in the U.S. While antibody drugs have made great strides in cancer therapies, crossing the blood-brain barrier (BBB) and ...
By Base Pair Biotechnologies, Inc. based in Pearland, TEXAS (USA).
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Microscopy Technology for Pathogens Hub
Infectious diseases are caused by pathogenic microorganisms such as bacteria, viruses, fungi or prions. Thanks to scientific advances in microbiology, host-pathogen interactions, and drug development, many of these infections can now be controlled or cured. Despite great efforts and the development of advanced technologies to investigate infectious agents, there are still many open questions regarding pathogen life cycles, how they cause disease and how can they be ...
By ONI based in Oxford, UNITED KINGDOM.
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Zenalux Technology in Pre-clinical and Clinical Applications
Zenalux technology has been applied to the quantitative optical analysis of tissues in a number of published studies in both pre-clinical models and in patients. In the breast, the Zenalux technology has been proven to be sensitive to sources of intrinsic optical contrast, in particular, hemoglobin, beta carotene and scattering which effectively discriminate diseased from healthy tissues (see Published Papers.) ...
By Zenalux Biomedical, Inc. based in Durham, NORTH CAROLINA (USA).
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Encoding Based on htDNA-chip®
In the era of global information, traditional storage technologies have been slightly tested. DNA must realize reliable information encoding. Only when DNA becomes a viable competitor of traditional storage technology is the first step for DNA to realize information storage. The most important thing is to produce nucleotide strings cheaply and quickly. For DNA, it is composed of four different monomers, consisting of a deoxyribonucleic acid having a skeleton with phosphoric acid. First, DNA is a polymer biological ...
By CD Biosciences - htDNA-chip® based in Shirley, NEW YORK (USA).
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Ceftriaxone Sodium
BOC Sciences is committed to supplying cost-effective products and services. We provide Ceftriaxone Sodium (Cas No:74578-69-1). More information, please visit the website: http://www.bocsci.com/ceftriaxone-sodium-cas-74578-69-1-item-97893.html ...
By BOC Sciences based in Shirley, NEW YORK (USA).
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Highly customized aptamer discovery solutions for therapeutic aptamers sector
As targeted therapies evolve and the limitations of antibody-based therapies become clearer, a growing number of research teams are exploring the therapeutic potential of ...
By Base Pair Biotechnologies, Inc. based in Pearland, TEXAS (USA).
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Highly customized aptamer discovery solutions for drug delivery sector
In many therapeutic areas, current treatments involve significant side effects. Combining drug compounds with affinity agents that target specific cell surface receptors can dramatically reduce off-target effects and improve treatment effectiveness. In several studies, aptamer-mediated drug delivery has reduced toxicity and improved drug performance. ...
By Base Pair Biotechnologies, Inc. based in Pearland, TEXAS (USA).
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Highly customized aptamer discovery solutions for hot areas for aptamers sector
Aptamers are short strands of DNA or RNA with unique secondary and tertiary structures that enable highly selective binding to various types of targets. While aptamers are similar to antibodies in their ability to specifically bind with high affinity, there are some key differences between antibodies and aptamers which have prompted an increase in aptamer development projects. Several hot areas for aptamers, along with specific aptamer advantages, are outlined below. ...
By Base Pair Biotechnologies, Inc. based in Pearland, TEXAS (USA).
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