Medical Specialties Articles
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Bear-Moon Clinical Case Study
The BEAR Implant is the first medical advancement to enable your body to heal its own torn anterior cruciate ligament (ACL). That’s a big deal, because until now your ACL would have been replaced with either another tendon from your body or a tendon from a deceased donor. The BEAR Implant is different because it works with your own blood to heal the torn ends of your ACL back ...
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Luna’s Story: Teen Trailblazer Becomes First BEAR Implant Patient in Connecticut
Very rarely does a high school student who aspires to study medicine get a first-hand opportunity to be a medical trailblazer. But 15-year-old Luna Martini stepped comfortably into that role when she became the first patient in Connecticut to receive a BEAR® Implant to treat her torn anterior cruciate ligament (ACL). A freshman at Farmington High School, Luna aspires to be a doctor herself ...
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What are Surgical Options for ACL Tears?
The anterior cruciate ligament, better known as the ACL, is one of the two ligaments in the center of your knee that connect the femur to the tibia. It’s also one of the most commonly injured, especially among athletes. Unlike many other ligaments in the body, the ACL does not have the ability to heal on its own. A thick liquid – called synovial fluid – reduces friction ...
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3 ways VisualDx boosts my confidence and saves me time as a nurse practitioner
Imagine you’re sipping (okay, realistically, chugging) your caffeinated beverage of choice in the morning as you log into your computer to take a peek at your schedule. Now think about what appointment type is guaranteed to drop ice-cold dread right into the pit of your stomach, because we for sure all have one. Now, don’t get me wrong, the cool thing about working in primary ...
By VisualDx
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First-in-Human Dose Finding Study of Venadaparib (IDX-1197), a Potent and Selective PARP inhibitor, in Patients with Advanced Solid Tumors
Poly ADP-ribose polymerase (PARP) is an enzyme that is central to the repair of DNA replication errors known as single-strand breaks. PARP inhibitors are currently approved (or ovary, breast, pancreatic and prostate cancers which harbor BRCA1/2 mutations and/or homologous recombinant repair mutation. In this phase 1 dose escalation study of venadaparib, we determined the maximum tolerated dose ...
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USA Today: Images of darker skin are absent from medical texts. Dermatologists are changing that
Nada Elbuluk, MD, MSc, FAAD, speaks to USA Today highlighting the importance of diversity in medical education, as well as Project IMPACT’s and VisualDx’s role in improving health equity. Dr. Nada Elbuluk is a board-certified dermatologist, the director of clinical impact at VisualDx, and founder of Project IMPACT. The highlights: Darker skin is underrepresented in medical ...
By VisualDx
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Teleradiology in Covid-19
The start of coronavirus pandemic pushed limits of healthcare systems all over the world by causing thousands of deaths and the requirement of a huge quantity of healthcare resources. When WHO declared COVID19 as a pandemic, the whole world came to standstill. Half of the world population is confined to their home except for essential services. In the year 2016, when GOI announced ...
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Peptide and Protein De Novo Sequencing by Mass Spectrometry
The method of peptide and protein de novo sequencing by mass spectrometry De novo sequencing is a method to analyze and identify peptide sequences and some post-translational modified proteins. Different from some other analysis methods, which depend on a known protein sequence database or a known mass spectrometry database, de novo sequencing uses tandem mass spectrometry for direct analysis ...
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New structural target against COVID-19
A new structural target for drug development against COVID-19 has been unveiled today by Sibylla Biotech in collaboration with the Italian National Institute of Nuclear Physics (INFN), the University of Trento and University of Perugia.The breakthrough drug discovery strategy pioneered by Sibylla in this study would not only promise to reduce the risk of drug resistance and harmful side effects, ...
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Top-Down Proteomics vs. Bottom-Up Proteomics
Protein research is one of the most challenging topics in analytical chemistry. Initial protein research focused on developing techniques capable of isolating and identifying major sequences (or portions) of proteins. The Edman degradation of peptides is a revolutionary method to identify the main amino acid sequence of a peptide. In addition, the whole sequence of proteins can be determined by ...
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Introduction to Protein Digestion—In-Gel or In-Solution
The most common endoprotease used for protein digestion is serine protease trypsin, which produces peptides that are highly amenable to MS/MS analysis. Depending on the preceding workflow, the enzymatic digestion of proteins is performed either in-gel or in-solution. Generally, the in-gel digestion methodology has become routine for proteins separated by 2-D electrophoresis while in-solution ...
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Movember Together: How Paige, University of Oxford, and Prostate Cancer UK Are Working to Change the Prostate Cancer Experience
Movember is an annual initiative where men from around the globe grow mustaches to raise awareness for men’s health causes, including mental health and suicide prevention, testicular cancer, and prostate cancer. Through events, fundraising, and using mustaches as a light-hearted starting point for important conversations, the movement supports men in taking charge of their health to live ...
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Achieving CDISC compliance in academia
CDISC compliance is mandatory for clinical trial submissions to the US Food and Drug Administration (FDA) and Pharmaceuticals and Medical Devices Agency (PMDA). The academic world is no exception. In fact, many academic institutions must achieve CDISC compliance in order to be granted funding for clinical research. CDISC standards can seem overwhelming, like a whole new language to be understood ...
By Formedix
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How ML Will Disrupt the Future of Clinical Radiology
The use of computer vision in radiology may have advantages for both patients and medical facilities. However, some worry that machine learning (ML) may one day replace doctors because it can outperform them. The desire for increased efficiency and efficacy in clinical care has been the primary motivating reason behind the development of AI in medical imaging. Recent technological developments, ...
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Introduction to Shotgun Metagenomics, From Sampling to Data Analysis
Metagenomics is the science that applies high-throughput sequencing technologies and bioinformatics tools to directly obtain the genetic content of a microbial community without the need to isolate and culture the individual microbial species. Metagenomics enables researchers not only to study the functional gene composition of microbial communities but also to conduct evolutionary research. ...
By CD Genomics
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What is high-throughput detection of gene expression
What Is High-Throughput Detection of Gene Expression? The high-throughput detection of gene expression relies on next generation sequencing technologies to assess the level of expression of all genes in the genome. These technologies have revolutionized transcriptomic research and we are now entering the ultra-high-throughput era of gene expression studies. In this article, we discuss the ...
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Biopharma PEG Provides Multi-arm PEG Derivatives Crosslinked Into Hydrogels
Polyethylene (ethylene glycol) is a hydrophilic polymer that can have a very high water content when cross-linked into a network. Polyethylene glycol (PEG) is a suitable material for biological applications because it does not normally elicit an immune response. Since the 1970s, PEG has been used to modify therapeutic proteins and peptides in order to increase their solubility, reduce their ...
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Huateng Pharma Develops Intermediates of Carfilzomib For Multiple Myeloma
Carfilzomib, a proteasome inhibitor, is indicated for the treatment of patients with multiple myeloma. Multiple myeloma (multiple myeloma, MM) is a malignant tumor originating from the B cell lineage, characterized by the clonal proliferation of malignant plasma cells in the bone marrow microenvironment, causing fractures and bone marrow failure, and is the second most common blood system ...
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DELEO invents Body-Layering nti-Âge Magazine – May 2021
Body-Layering® is slowly revolutionising the medical aesthetics industry. By combining three cutting-edge technologies, it allows for a global approach. For the fi rst time, the fi gure can be refi ned, sculpted and toned using non-invasive technologies. With the arrival of the CRISTAL PRO, CRISTAL FIT and CRISTAL SKIN trio, DELEO is helping aesthetic medicine to reach for new horizons.This ...
By DELEO
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Cryo Cristal: The latest slimming technique
Medical cryolipolysis is a non-invasive adipocyte lysis technique. The principle of cryolipolysisis to apply intense cooling to a localized fat deposit with an applicator that cools the localized area down to -9°C. This new procedure crystallisesfat cells, which then self-destruct due to the cold temperature. The crystallisedfat is removed naturally and permanently by your body in the weeks ...
By DELEO
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